Ficlatuzumab (anti-HGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to HGF, >95%, Human IgG1, INHIBITOR of Hepatocyte growth factor inhibitor, INHIBITOR of Hepatocyte growth factor inhibitor

CAS: 1174900-84-5 Cat. No.: Ab170563
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab170563-100μg
10
131,90US$
1mg
Ab170563-1mg
4
659,90US$
5mg
Ab170563-5mg
1
1.659,90US$
10mg
Ab170563-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
2.659,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion.

Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Ficlatuzumab (anti-HGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to HGF, >95%, Human IgG1, INHIBITOR of Hepatocyte growth factor inhibitor
Sinónimos
Hepatopoietin-A | Scatter factor | SF
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
HGF
Aplicación
ELISA, Functional Assay, Flow cytometry, Kinetics (BLI), Kinetics (SPR)
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Hepatocyte growth factor inhibitor
Tipo de anticuerpo
Primary antibody
Clonalidad
Recombinant
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
SDS-PAGE
27.6 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 178.7 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Pureza
>95%
Fuente
CHO supernatant
Concentración
See COA
CAS
1174900-84-5
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Ficlatuzumab (anti-HGF) (Ab170563) - ELISA
Immobilized Recombinant human HGF protein (rp156180) at 1.0 μg/mL can bind Ficlatuzumab (anti-HGF) (Ab170563) with the EC₅₀ of 45.64 ng/mL.

Ficlatuzumab (anti-HGF) (Ab170563) - SEC
The purity of Ficlatuzumab (anti-HGF) (Ab170563) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
HGF Tchem Hepatocyte growth factor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0303070Certificate of AnalysisDec 16, 2025 Ab170563
ZJ24F0303071Certificate of AnalysisDec 16, 2025 Ab170563
ZJ24F0303072Certificate of AnalysisDec 16, 2025 Ab170563
Citations of This Product
Referencias
1. Yang Shu, Rong Xue, Yiru Gao, Wenxin Zhang, Jianhua Wang.  (2022)  A thermo-responsive hydrogel loaded with an ionic liquid microemulsion for transdermal delivery of methotrexate.  Journal of Materials Chemistry B,  11  (24): (5494-5502).  [PMID:36458850] [10.1039/D2TB02189G]
2. Shanmeiyu Zhang, Yanyan Zhang, Chongchong Wu, Hui Yang, Qiqi Zhang, Fuyi Wang, Jingyi Wang, Ian Gates, Jinben Wang.  (2021)  A Facile Strategy to Prepare Small Water Clusters via Interacting with Functional Molecules.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  22  (15): (8250).  [PMID:34361016] [10.3390/ijms22158250]
3. Xie Zongliang, Zhang Xiayu, Wang Hailan, Huang Cheng, Sun Haodong, Dong Mengyang, Ji Lei, An Zhongfu, Yu Tao, Huang Wei.  (2021)  Wide-range lifetime-tunable and responsive ultralong organic phosphorescent multi-host/guest system.  Nature Communications,  12  (1): (1-8).  [PMID:34112793] [10.1038/s41467-021-23742-4]
4. Lanlan Wei, Dongrui Zhou, Xuejun Kang.  (2021)  Electrospinning as a novel strategy for the encapsulation of living probiotics in polyvinyl alcohol/silk fibroin.  Innovative Food Science & Emerging Technologies,      [PMID:] [10.1016/j.ifset.2021.102726]
5. Huang Jiming, Huang Ding, Zeng Fanbao, Ma Long, Wang Zhengbang.  (2020)  Photocatalytic MOF fibrous membranes for cyclic adsorption and degradation of dyes.  JOURNAL OF MATERIALS SCIENCE,  56  (4): (3127-3139).  [PMID:] [10.1007/s10853-020-05473-x]
6. Xiu-Qing Qiao, Zhen-Wei Zhang, Qiu-Hao Li, Dongfang Hou, Qichun Zhang, Jian Zhang, Dong-Sheng Li, Pingyun Feng, Xianhui Bu.  (2018)  In situ synthesis of n–n Bi2MoO6 & Bi2S3 heterojunctions for highly efficient photocatalytic removal of Cr(VI).  Journal of Materials Chemistry A,  (45): (22580-22589).  [PMID:] [10.1039/C8TA08294D]
7. Yiwen Zhang, Zixuan Tang, Liyun Chen, Min Yang, Yating Zeng, Xujue Bai, Bingna Zhang, Jianda Zhou, Wancong Zhang, Shijie Tang.  (2025)  Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.  JOURNAL OF CONTROLLED RELEASE,      [PMID:39724946] [10.1016/j.jconrel.2024.12.055]
8. Junpeng Liu, Wei Liu, Yefan Zhang, Junwen Ouyang, Boxiao Zhao, Changyu Wu, Boda Li, Jiaxuan Jiang, Kai Hu.  (2025)  Injectable High-Adhesion Fibrinogen-Silk Fibroin Hydrogel Loaded with Curcumin Accelerates Pterygium Repair via Dual Anti-Inflammatory/Antiproliferative Mechanisms.  ACS Applied Materials & Interfaces,      [PMID:40910581] [10.1021/acsami.5c12778]
9. Jiahang Yu, Mingyuan Huang, Huixin Tian, Xinglian Xu.  (2023)  Silver Nanoparticle Sensor Array-Based Meat Freshness Inspection System.  Foods,  12  (20): (3814).  [PMID:37893707] [10.3390/foods12203814]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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