Fremanezumab (anti-CALCA) - Primary antibody, specific to CALCA, >95% (SDS-PAGE&SEC), Human IgG2SA, ANTAGONIST of Calcitonin gene-related peptide antagonist, ANTAGONIST of Calcitonin gene-related peptide antagonist

CAS: 1655501-53-3 Cat. No.: Ab175765
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Human
Isotype
Human IgG2SA
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab175765-100μg
10
95,90US$
1mg
Ab175765-1mg
4
479,90US$
5mg
Ab175765-5mg
1
1.197,90US$
10mg
Ab175765-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
1.881,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Fremanezumab (anti-CALCA) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab (anti-CALCA) has the potential for chronic migraine research.
Purity>95% (SDS-PAGE&SEC)
Endotoxin Level< 0.01EU/μg

Specifications

Product Name
Fremanezumab (anti-CALCA) - Primary antibody, specific to CALCA, >95% (SDS-PAGE&SEC), Human IgG2SA, ANTAGONIST of Calcitonin gene-related peptide antagonist
Sinónimos
Calcitonin/calcitonin related polypeptide alpha antibody | Alpha type CGRP antibody | Beta type CGRP antibody | CALC1 antibody | CALC2 antibody | CALCA antibody | CALCB antibody | Calcitonin 1 antibody | Calcitonin 2 antibody | Calcitonin gene related pep
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
CALCA
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Recombinant, Validated
Tipo de acción
ANTAGONIST
Mecanismo de acción
ANTAGONIST of Calcitonin gene-related peptide antagonist
Isotipo
Human IgG2SA
Tipo de cadena ligera
kappa
SDS-PAGE
27.2 kDa (Light Chain) & 49.8 kDa (Heavy Chain), under reducing conditions; 160.5 kDa, under non-reducing conditions.
Método de purificación
Protein A purified
Pureza
>95% (SDS-PAGE&SEC)
Concentración
See COA
CAS
1655501-53-3
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Fremanezumab (anti-CALCA) (Ab175765) - ELISA
Immobilized hu-CALCA-KLH at 2 μg/mL can bind Fremanezumab (anti-CALCA) (Ab175765) with the EC₅₀ of 6.76 ng/mL.

Fremanezumab (anti-CALCA) (Ab175765) - SEC
The purity of Fremanezumab (anti-CALCA) (Ab175765) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
CALCA Tclin Calcitonin gene-related peptide 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CALCA Tbio Calcitonin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CALCA Tclin Calcitonin gene-related peptide 1 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0404233Certificate of AnalysisFeb 11, 2026 Ab175765
ZJ24F0404234Certificate of AnalysisFeb 11, 2026 Ab175765
ZJ24F0404235Certificate of AnalysisFeb 11, 2026 Ab175765
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Azide Free grade guide →

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