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Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor ( NK-1R ), disrupting the binding of substance P (SP) to NK-1R . This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c ( Cytochrome c ), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1 . N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .
| Isomeric SMILES | CC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O |
|---|---|
| WGK Germany | 2 |
| RTECS | YN6160000 |
| Molecular Weight | 246.26 |
| Beilstein | 22(3/4)6781 |
| Reaxy-Rn | 487262 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=487262&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Specific Rotation[α] | 26 ° (C=1, 1mol/L NaOH) |
|---|---|
| Melt Point(°C) | 186°C |
| 1. Xiuzhen Qiu, Weimao Chen, Yiling Luo, Yulin Wang, Yanlian Wang, Huishi Guo. (2019) Highly sensitive α-amanitin sensor based on molecularly imprinted photonic crystals. ANALYTICA CHIMICA ACTA, [PMID:31735207] [10.1016/j.aca.2019.09.066] |
| 2. Qici Wu, Qilei Zhang, Shiwen Xu, Chengtong Ge, Shanjing Yao, Dongqiang Lin. (2017) Preparation and evaluation of mixed-mode resins with tryptophan analogues as functional ligands for human serum albumin separation. CHINESE JOURNAL OF CHEMICAL ENGINEERING, [PMID:] [10.1016/j.cjche.2016.12.010] |
| 3. Yuting Li, Xiaotong Li, Jinshun Ye, Zhenzhao Weng, Xiaozhen Liu, Fengyuan Liu, Jingkun Yan, Lin Li. (2024) Reactivity of amino acid residues towards 4-methylbenzoquinone: Effect on the site-specificity of quinone-protein reaction. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2024.116217] |
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