Polatuzumab (anti-CD79b) - Primary antibody, specific to CD79B, >95% (SDS-PAGE&SEC), Human IgG1

CAS: 2279068-37-8 Cat. No.: Ab175715

GRADE & PURITY Animal Free, Carrier Free, Recombinant, Validated, ExactAb™, Azide Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Human

Reactive species

Cynomolgus monkey, Human, Mouse

Isotype

Human IgG1

Conjugation

Unconjugated

Descripción general

Polatuzumab (anti-CD79b) is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab (anti-CD79b) sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab (anti-CD79b) can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b.
Purity>95% (SDS-PAGE&SEC)
Endotoxin Level< 0.01EU/μg

Specifications

Product Name

Polatuzumab (anti-CD79b) - Primary antibody, specific to CD79B, >95% (SDS-PAGE&SEC), Human IgG1

Sinónimos

AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein B29 antibody | B-cell antigen receptor complex-associated protein beta chain antibody | B-cell-specific glycoprotein B29 antibody | B29 a

Especificaciones y pureza

Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Especies hospedadoras

Human

Especificidad

CD79B

Conjugación

Unconjugated

Grado

Animal Free, Azide Free, Carrier Free, ExactAb™, Recombinant, Validated

Isotipo

Human IgG1

Tipo de cadena ligera

kappa

SDS-PAGE

27.4 kDa (Light Chain) & 51.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.

Método de purificación

Protein A purified

Pureza

>95% (SDS-PAGE&SEC)

Concentración

See COA

CAS

2279068-37-8

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at -80°C,Avoid repeated freezing and thawing

Enviado en

Dry ice packs + Cold packs

Estabilidad y almacenamiento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imágenes

ELISA: Polatuzumab (anti-CD79b) (Ab175715)

Polatuzumab (anti-CD79b) (Ab175715) - ELISA
Immobilized hu-CD79b-His at 2 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC₅₀ of 4.09 ng/mL.

SEC: Polatuzumab (anti-CD79b) (Ab175715)

Polatuzumab (anti-CD79b) (Ab175715) - SEC
The purity of Polatuzumab (anti-CD79b) (Ab175715) is more than 95% verified by HPLC.

ELISA: Recombinant Human CD79B Protein (rp176729)

Recombinant Human CD79B Protein (rp176729) - ELISA
Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL.

Objetivos asociados (humanos)

CD79B Tclin B-cell antigen receptor complex-associated protein beta chain (0 Activities)

Discover Target: CD79B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción