Prasinezumab (anti-Alpha-synuclein) - Primary antibody, specific to SNCA, Human IgG1-REM, BINDING AGENT of Alpha-synuclein binding agent, BINDING AGENT of Alpha-synuclein binding agent

CAS: 1960462-19-4 Cat. No.: Ab182835
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Mouse
Isotype
Human IgG1-REM
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab182835-100μg
5
133,90US$
1mg
Ab182835-1mg
2
663,90US$
5mg
Ab182835-5mg
1
1.999,90US$
10mg
Ab182835-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
3.199,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Prasinezumab (anti-Alpha-synuclein) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab (anti-Alpha-synuclein) has the potential for Parkinson's disease research.

Specifications

Product Name
Prasinezumab (anti-Alpha-synuclein) - Primary antibody, specific to SNCA, Human IgG1-REM, BINDING AGENT of Alpha-synuclein binding agent
Sinónimos
Alpha synuclein antibody | Alpha-synuclein antibody | Alpha-synuclein, isoform NACP140 antibody | alphaSYN antibody | MGC105443 antibody | MGC110988 antibody | MGC127560 antibody | MGC64356 antibody | NACP antibody | Non A beta component of AD amyloid ant
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Post-translation
Especies hospedadoras
Human
Especificidad
SNCA
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
BINDING AGENT
Mecanismo de acción
BINDING AGENT of Alpha-synuclein binding agent
Isotipo
Human IgG1-REM
Tipo de cadena ligera
kappa
SDS-PAGE
145.26 kDa
Método de purificación
Protein A purified
Concentración
See COA
CAS
1960462-19-4
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Prasinezumab (anti-Alpha-synuclein) (Ab182835) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling Alpha-synuclein (red) with Prasinezumab (anti-Alpha-synuclein) (Ab182835). Goat Anti-Human IgG (APC) (Ab175837) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Prasinezumab (anti-Alpha-synuclein) (Ab182835) - ELISA
Immobilized Recombinant Human Alphasynuclein-1-140-chis protein at 2.0 μg/mL can bind Prasinezumab (anti-Alpha-synuclein) (Ab182835) with the EC₅₀ of 27.65 ng/mL.

Prasinezumab (anti-Alpha-synuclein) (Ab182835) - SEC
The purity of Prasinezumab (anti-Alpha-synuclein) (Ab182835) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
SNCA Tchem Alpha-synuclein (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0910985Certificate of AnalysisJul 10, 2026 Ab182835
ZJ24F0910986Certificate of AnalysisJul 10, 2026 Ab182835
ZJ24F0910987Certificate of AnalysisJul 10, 2026 Ab182835
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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