Saponin - BioReagent, 10~25% , CAS No.8047-15-2

CAS: 8047-15-2 Cat. No.: S108691 Número EC: 232-462-6 PubChem CID: 198016

GRADE & PURITY BioReagent, 10~25%

Synonyms

SAPONIN | BRN 0078682 | Olean-29-al, 13,28-epoxy-3-((O-beta-D-glucopyranosyl-(1-3)-O-(beta-D-xylopyranosyl-(1-2))-O-beta-D-glucopyranosyl-(1-4)-O-(beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)oxy)-16-hydroxy-, (3-beta,16-alpha,20-beta)- | NSC 104

Storage

Argon charged,Room temperature

Shipped In

Normal

Descripción general

Saponin is a secondary metabolite that facilitates the penetration of proteins through the cell membrane. Studies indicate that saponins are amphipathic glycosides, which can act as hemolytic agents. Research indicates that Saponin displays antinociceptive, anti-inflammatory and antipyretic activities, which may be due to its nonglycosidic moiety, sapogenin. Saponin can also be used in environmental research to recover chromium and other metals from sludge samples. Additional studies indicate that Saponin is useful in immunoassays since it can stimulate the Th1 immune response and the production of cytotoxic T-lymphocytes in response to exogenous antigens.
An amphipathic glycoside and surfactant

Specifications

Sinónimos

SAPONIN | BRN 0078682 | Olean-29-al, 13, 28-epoxy-3-((O-beta-D-glucopyranosyl-(1-3)-O-(beta-D-xylopyranosyl-(1-2))-O-beta-D-glucopyranosyl-(1-4)-O-(beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)oxy)-16-hydroxy-, (3-beta, 16-alpha, 20-beta)- | NSC 104

Especificaciones y pureza

BioReagent, 10~25%

Mecanismos bioquímicos y fisiológicos

对人经口内服几乎没有毒性，但静脉注射到血液中，有强烈溶血作用。毒性极大，最小致死量(小鼠，经口)3000mg/kg。有刺激性。从油茶籽中提取茶皂素（Tea Saponin），属于三萜类皂甙，是一种性能优良的非离子型天然表面活性剂，它具有较强的发泡、乳化、分散、润湿作用。

Condiciones de almacenamiento de almacenamiento

Argon charged, Room temperature

Enviado en

Normal

Grado

BioReagent

Nombres e identificadores

• Sonrisas canónicas: CC1(C2CCC3(C(C2(CCC1OC4C(C(C(CO4)OC5C(C(C(CO5)O)O)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CCC91C3(CC(C2(C9CC(CC2)(C)C=O)CO1)O)C)C)C
• IUPAC Name: (2R,4S,5R,10S,13R,14R,18S,20R)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-2-hydroxy-4,5,9,9,13,20-hexamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracosane-20-carbaldehyde
• InChIKey: MAEBCGDGGATMSC-OSHGGGOQSA-N
• INCHI: 1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
• Isómeros SMILES: C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
• PubChem CID: 198016

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Prenol lipids
      • Subclass Triterpenoids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Prenol lipids
• Subclass: Triterpenoids
• Intermediate Tree Nodes: Not available
• Direct Parent: Triterpenoids
• Alternative Parents: Oligosaccharides O-glycosyl compounds Oxepanes Oxanes Tetrahydrofurans Secondary alcohols Cyclic alcohols and derivatives Polyols Oxacyclic compounds Dialkyl ethers Acetals Primary alcohols Organic oxides Hydrocarbon derivatives Aldehydes
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Triterpenoid - Oligosaccharide - O-glycosyl compound - Glycosyl compound - Oxepane - Oxane - Tetrahydrofuran - Cyclic alcohol - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Polyol - Ether - Dialkyl ether - Acetal - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Aldehyde - Alcohol - Aliphatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water.
• Sensibilidad: Hygroscopic

Referencias

1. Jie He, Youfa Xie, Junzhen Zhong, Wenrong Chen, Suqiong Fang, Xing Chen, Shengfeng Peng, Wei Liu, Chengmei Liu.  (2023)  Improving shikonin solubility and stability by encapsulation in natural surfactant-coated shikonin nanoparticles.  JOURNAL OF FOOD SCIENCE,  88  (2): (825-836).  [PMID:36625167] [10.1111/1750-3841.16445]

2. Xiaonan Chen, Yiqing Zou, Shuqi Zhang, Pengchao Fang, Shuxuan Li, Pengyu Li, Yingying Sun, Gang Yuan, Haiyan Hu.  (2022)  Multi-functional vesicles improve Helicobacter pylori eradication by a comprehensive strategy based on complex pathological microenvironment.  Acta Pharmaceutica Sinica B,      [PMID:36176916] [10.1016/j.apsb.2022.05.014]

3. Xi Yang, Yuan-Yuan Zang, Sha Yang, Zhi-Gang Chen.  (2020)  Green and efficient removal of heavy metals from Porphyra haitanensis using natural deep eutectic solvents.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  101  (7): (2930-2939).  [PMID:33155677] [10.1002/jsfa.10925]

4. Guosong Xin, Miao Yu, Yang Hu, Shiyong Gao, Zheng Qi, Yuan Sun, Wenjing Yu, Jiaxin He, Yubin Ji.  (2020)  Effect of lycorine on the structure and function of hepatoma cell membrane in vitro and in vivo.  BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT,      [PMID:] [10.1080/13102818.2020.1719019]

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6. Shengfeng Peng, Ziling Li, Liqiang Zou, Wei Liu, Chengmei Liu, David Julian McClements.  (2018)  Improving curcumin solubility and bioavailability by encapsulation in saponin-coated curcumin nanoparticles prepared using a simple pH-driven loading method.  Food & Function,  9  (3): (1829-1839).  [PMID:29517797] [10.1039/C7FO01814B]

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9. Datong Liu, Sijie Lei, Yang Hu, Zhanguo Li, Hailing Xi, Xiaoyan Lin.  (2023)  Environmentally friendly tea saponin foam detergents costabilized by GO-OH/SiO2 nanoparticles for removing radioactive surface contaminants.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2023.132667]

10. Li Cuifeng, Li Yuxin, Zhou Bini, Li Tong, Wei Xiaohui, Chen Kun, Chen Wenlong, Shi Ziwei, Dai Xiaobin, Zhang Jiachen, Yang Chen, Ji Zhenglin, Sun Wenbo, Gao Ji, Wu Jing, Zhao Binbin, Min Xin, Li Yujie, Lin Lin, Yang Wei, Wang Min, Liu Zezhong, Liu Yaping, Zhu Chenyou, Yang Bo, Xu Jiang-Fei, Yan Li-Tang, Shi Yi, Lu Lu, Zhang Linqi, Ding Qiang, Xue Jing, Hou Baidong, Qi Hai, Liu Jiangning, Yang Yuhe R., Liu Dongsheng, Liu Wanli.  (2025)  Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections.  Nature Biomedical Engineering,      [PMID:40628957] [10.1038/s41551-025-01431-7]

11. Lei Sijie, Lin Xiaoyan, Han Qiang.  (2024)  Polyamidoxime and graphene oxide synergistically stabilized foam decontaminant for removal of radioactive surface contaminants.  JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,      [PMID:] [10.1007/s10967-024-09634-z]

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13. Ping Li, Yuan Lv, Sainan Yang, Keqian Xu, Haiyong Luo, Qian Liu, Bin Dai.  (2025)  Colorimetric Smartphone-Based Dry Assay for the Determination of Hemoglobin.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2025.2511884]

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