Semorinemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG4SP-Opti, INHIBITOR of Microtubule-associated protein tau inhibitor, INHIBITOR of Microtubule-associated protein tau inhibitor

CAS: 2159141-27-0 Cat. No.: Ab182842
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG4SP-Opti
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab182842-100μg
5
107,90US$
1mg
Ab182842-1mg
2
533,90US$
5mg
Ab182842-5mg
1
1.333,90US$
10mg
Ab182842-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
2.139,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Semorinemab (anti-Tau) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab (anti-Tau) binds with human Tau with a Kd value of 3.8 nM. Semorinemab (anti-Tau) can be used for the research of Alzheimer's Disease.

Specifications

Product Name
Semorinemab (anti-Tau) - Primary antibody, specific to MAPT, Human IgG4SP-Opti, INHIBITOR of Microtubule-associated protein tau inhibitor
Sinónimos
AI413597 antibody | AW045860 antibody | DDPAC antibody | FLJ31424 antibody | FTDP 17 antibody | G protein beta1/gamma2 subunit interacting factor 1 antibody | MAPT antibody | MAPTL antibody | MGC134287 antibody | MGC138549 antibody | MGC156663 antibody |
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Mecanismos bioquímicos y fisiológicos
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functi
Especies hospedadoras
Human
Especificidad
MAPT
Conjugación
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Mecanismo de acción
INHIBITOR of Microtubule-associated protein tau inhibitor
Isotipo
Human IgG4SP-Opti
Tipo de cadena ligera
kappa
SDS-PAGE
145 kDa
Método de purificación
Protein A purified
Concentración
See COA
CAS
2159141-27-0
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Semorinemab (anti-Tau) (Ab182842) - ELISA
Immobilized Recombinant N-His-hu-flTau(2-441aa) protein at 2.0 μg/mL can bind Semorinemab (anti-Tau) (Ab182842) with the EC ₅₀  of 4.58 ng/mL.

Semorinemab (anti-Tau) (Ab182842) - SEC
The purity of Semorinemab (anti-Tau) (Ab182842) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
MAPT Tclin Microtubule-associated protein tau (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAPT Tclin Microtubule-associated protein tau (95507 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPT Tclin KEAP1/Microtubule-associated protein tau (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAPT Tclin KEAP1/Cullin-3/Microtubule-associated protein tau (13 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0910867Certificate of AnalysisJul 10, 2026 Ab182842
ZJ24F0910868Certificate of AnalysisJul 10, 2026 Ab182842
ZJ24F0910869Certificate of AnalysisJul 10, 2026 Ab182842
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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