1-Boc-piperazine - 10mM in DMSO , CAS No.57260-71-6

CAS: 57260-71-6 Cat. No.: B660492 Molecular Weight: 186.25 Beilstein Registry Number: 879985 EC Number: 611-489-0

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

1-Boc-piperazine is an N-Boc protected piperazine. Crosscoupling of 1-Boc-piperazine with aryl iodides using CuBr/1,1′-bi-2-naphthol (catalyst) and K3PO4 (base) has been reported.1-Boc-piperazine undergoes Buchwald-Hartwig coupling reactions with aryl halides.1-Boc-piperazine can be prepared in 80% yield via solvent-free N-Boc protection catalyzed by iodine
1-Boc-piperazine was used in Buchwald-Hartwig coupling reaction

Specifications

Specifications & Purity

10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CC(C)(C)OC(=O)N1CCNCC1
• WGK Germany: 3
• Alternate CAS: 143238-38-4
• Molecular Weight: 186.25
• Beilstein: 879985
• Reaxy-Rn: 879985
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=879985&ln=

Chemical and Physical Properties

• Solubility: Soluble in ethyl acetate, methanol and water.
• Sensitivity: Air Sensitive;Hygroscopic ;Heat sensitive
• Flash Point(°F): 235.4 °F
• Flash Point(°C): 113 °C
• Melt Point(°C): 43-47°C

References

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2. Wenwen Guo, Shun Chen, Fuwei Liang, Liping Jin, Chenpeng Ji, Ping Zhang, Bin Fei.  (2023)  Ultra-light-weight, anti-flammable and water-proof cellulosic aerogels for thermal insulation applications.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37331534] [10.1016/j.ijbiomac.2023.125343]

3. Guoqiang Liu, Hongwei Ge, Ranhao Yin, Long Yu, Congming Sun, Weiru Dong, Zhenli Sun, Khalid A. Alamry, Hadi M. Marwani, Suhua Wang.  (2020)  Carbon dots tailored with a fluorophore for sensitive and selective detection of hydrogen sulfide based on a ratiometric fluorescence signal.  Analytical Methods,  12  (12): (1617-1623).  [PMID:] [10.1039/D0AY00020E]

4. Zengfeng Wei, Xin Chen, Jiang Duan, Caihong Mei, Dan Xiao, Aidong Zhang.  (2019)  Precision synthesis of 3-substituted urushiol analogues and the realization of their urushiol-like performance.  RSC Advances,  9  (43): (24904-24914).  [PMID:35528654] [10.1039/C9RA04981A]

5. Tang Gang, Hu Yang, Fang Yuan, Guan Mengfan, Gong Zedong, Wang Guodong, Deng Dan, Liu Xiuyu.  (2024)  Synthesis of a tris(DOPO-grafted piperazine)-triazine phosphoramide and its application as a highly efficient flame retardant for epoxy resins.  JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,      [PMID:] [10.1007/s10973-024-13508-7]