Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥96% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | -1.3 |
|---|
| Pubchem Sid | 488189681 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488189681 |
| Canonical Smiles | CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N |
| IUPAC Name | (2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid |
| InChIKey | ZADWXFSZEAPBJS-SNVBAGLBSA-N |
| INCHI | 1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1 |
| Isomeric SMILES | CN1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)N |
| WGK Germany | 3 |
| Molecular Weight | 218.25 |
| Reaxy-Rn | 20071 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20071&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Indoles and derivatives |
| Subclass | Indolyl carboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indolyl carboxylic acids and derivatives |
| Alternative Parents | 3-alkylindoles D-alpha-amino acids N-alkylindoles Aralkylamines Benzenoids N-methylpyrroles Heteroaromatic compounds Amino acids Carboxylic acids Azacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds Organic oxides Monoalkylamines |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Indolyl carboxylic acid derivative - Alpha-amino acid - Alpha-amino acid or derivatives - N-alkylindole - D-alpha-amino acid - 3-alkylindole - Indole - Aralkylamine - N-methylpyrrole - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Amino acid or derivatives - Amino acid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as indolyl carboxylic acids and derivatives. These are compounds containing a carboxylic acid chain (of at least 2 carbon atoms) linked to an indole ring. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 11, 2026 | M115830 | |
| Certificate of Analysis | Mar 11, 2026 | M115830 | |
| Certificate of Analysis | Mar 11, 2026 | M115830 | |
| Certificate of Analysis | Oct 10, 2025 | M115830 | |
| Certificate of Analysis | May 08, 2024 | M115830 | |
| Certificate of Analysis | May 08, 2024 | M115830 | |
| Certificate of Analysis | Jan 20, 2023 | M115830 | |
| Certificate of Analysis | Mar 12, 2022 | M115830 |
| Melt Point(°C) | 242-245°C |
|---|---|
| Molecular Weight | 218.250 g/mol |
| XLogP3 | -1.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 218.106 Da |
| Monoisotopic Mass | 218.106 Da |
| Topological Polar Surface Area | 68.300 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 270.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xinpei Liu, Xuan Yi, Jingyu Gu, Zhongfang Ji, Minqian Zhu, Mengling Shen, Yuanyuan Ren, Li Guo, Teng Liu, Nan Ding, Kai Yang. (2023) Immunoregulatory liposomes hitchhiking on neutrophils for enhanced carbon ion radiotherapy-assisted immunotherapy of glioblastoma. Nano Today, [PMID:] [10.1016/j.nantod.2023.102037] |
| 2. Shikai Zhang, Qing Xu, Changbo Ji, Xiaoyu Han, Yang Zhou, Chao Liang, Linran Ma, Weijian Sun, Yanling Li, Zhengyou Yang, Fengchun Zhao, Yuan Tian. (2023) Study on secondary metabolites of endophytic fungus Diaporthe sp. AC1 induced by tryptophan analogs. Frontiers in Microbiology, [PMID:37876783] [10.3389/fmicb.2023.1254609] |
| 3. Ping Huang, Yao Yang, Wenyan Wang, Zimu Li, Nansha Gao, Hongzhong Chen, Xiaowei Zeng. (2023) Self-driven nanoprodrug platform with enhanced ferroptosis for synergistic photothermal-IDO immunotherapy. BIOMATERIALS, [PMID:37196407] [10.1016/j.biomaterials.2023.122157] |
| 4. Li Xiangfei, Qiao Juan, Sun Yongjun, Li Zhiwei, Qi Li. (2021) Ligand-modulated synthesis of gold nanoclusters for sensitive and selective detection of folic acid. Journal of Analytical Science and Technology, 12 (1): (1-8). [PMID:] [10.1186/s40543-021-00266-6] |
| 5. Qilin Li, Jia Liu, Huiling Fan, Lin Shi, Yan Deng, Lei Zhao, Mengxi Xiang, Yunruo Xu, Xulin Jiang, Guobin Wang, Lin Wang, Zheng Wang. (2020) IDO-inhibitor potentiated immunogenic chemotherapy abolishes primary tumor growth and eradicates metastatic lesions by targeting distinct compartments within tumor microenvironment. BIOMATERIALS, [PMID:33172606] [10.1016/j.biomaterials.2020.120388] |
| 6. Wenshuai Li, Saipeng Huang, Huiyun Wen, Yane Luo, Jiewei Cheng, Zhao Jia, Pu Han, Weiming Xue. (2019) Pyridine functionalized carbon dots for specific detection of tryptophan in human serum samples and living cells. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2019.104579] |
| 7. Li Liao, Yufei Liu, Xianhai Li, Zewei Jiang, Zhijie Jiang, Jing Yao. (2025) Dual-Regulated Biomimetic Nanocomposites For Promoted Tumor Photodynamic Immunotherapy. ACS Applied Materials & Interfaces, [PMID:40159083] [10.1021/acsami.5c00763] |
| 8. Xiaorong Kou, Xue Wu, Tao He, Liping Bai, Xinchao Li, Rui Luo, Yangsong Xu, Yixi Wang, Meiling Shen, Changyang Gong, Qinjie Wu. (2026) Tumor-activated dual metabolic nanomodulator turns over tolerogenic tumor control and unleashes systemic immune responses. JOURNAL OF NANOBIOTECHNOLOGY, [PMID:41629977] [10.1186/s12951-026-04086-x] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →