Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2-(4-Hydroxyphenyl)ethanol is a phenolic compound present in olives, which can exhibit a wide range of health benefits and pharmacological properties like anti-inflammatory, antiviral, anti-tumor and cardioprotection activity.
| Pubchem Sid | 488181126 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181126 |
| Canonical Smiles | C1=CC(=CC=C1CCO)O |
| IUPAC Name | 4-(2-hydroxyethyl)phenol |
| InChIKey | YCCILVSKPBXVIP-UHFFFAOYSA-N |
| INCHI | 1S/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H2 |
| Isomeric SMILES | C1=CC(=CC=C1CCO)O |
| WGK Germany | 3 |
| Molecular Weight | 138.16 |
| Beilstein | 1859884 |
| Reaxy-Rn | 1859884 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1859884&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | Tyrosols and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Tyrosols |
| Alternative Parents | 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Primary alcohols Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Tyrosol - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as tyrosols. These are organic aromatic compounds containing a phenethyl alcohol moiety that carries a hydroxyl group at the 4-position of the benzene group. |
| External Descriptors | an aromatic compound |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 27, 2026 | H106325 | |
| Certificate of Analysis | Mar 20, 2026 | H106325 | |
| Certificate of Analysis | Jan 10, 2026 | H106325 | |
| Certificate of Analysis | Jan 10, 2026 | H106325 | |
| Certificate of Analysis | Jan 10, 2026 | H106325 | |
| Certificate of Analysis | Jan 10, 2026 | H106325 | |
| Certificate of Analysis | May 15, 2025 | H106325 | |
| Certificate of Analysis | May 15, 2025 | H106325 | |
| Certificate of Analysis | May 15, 2025 | H106325 | |
| Certificate of Analysis | Jun 26, 2024 | H106325 | |
| Certificate of Analysis | Jun 18, 2024 | H106325 | |
| Certificate of Analysis | Jun 18, 2024 | H106325 | |
| Certificate of Analysis | Aug 09, 2023 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Oct 27, 2022 | H106325 | |
| Certificate of Analysis | Jul 01, 2022 | H106325 | |
| Certificate of Analysis | Jul 01, 2022 | H106325 | |
| Certificate of Analysis | Jul 01, 2022 | H106325 | |
| Certificate of Analysis | Jul 01, 2022 | H106325 | |
| Certificate of Analysis | Jan 24, 2022 | H106325 |
| Solubility | Soluble in water; Soluble in Chloroform,Methanol,Benzene,Acetone,Ethanol |
|---|---|
| Boil Point(°C) | 310°C |
| Melt Point(°C) | 90-95°C |
| Molecular Weight | 138.160 g/mol |
| XLogP3 | 0.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 138.068 Da |
| Monoisotopic Mass | 138.068 Da |
| Topological Polar Surface Area | 40.500 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 85.300 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Chenchen Zhao, Yu Sha, Wei Zhuang, Yuan Rao, Jihang Zhang, Jinglan Wu, Tao Shen, Zhuotao Tan, Chenjie Zhu, Hongman Zhang, Hanjie Ying. (2023) Production of hydroxytyrosol from tyrosol via controllable oxidation with immobilized tyrosinase: A comparative study. PROCESS BIOCHEMISTRY, [PMID:] [10.1016/j.procbio.2023.06.017] |
| 2. Tong Sun, Yan Liu, Ke Wang, Feiyu Duan, Lili Lu. (2023) Biotransformation of Tyrosol into a Novel Valuable α-Galactoside with Increased Solubility and Improved Anti-inflammatory Activities. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:37319317] [10.1021/acs.jafc.3c02529] |
| 3. Jue Chen, Qibin Cheng, Qianqian Ma, Yuqi Wu, Liwei Zhang. (2023) Salidroside synthesis via glycosylation by β-D-glucosidase immobilized on chitosan microspheres in deep eutectic solvents. BIOCATALYSIS AND BIOTRANSFORMATION, [PMID:] [10.1080/10242422.2023.2178308] |
| 4. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang. (2022) Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China). Foods, 12 (1): (7). [PMID:36613224] [10.3390/foods12010007] |
| 5. Jinbin Liu, Kaipeng Wang, Mian Wang, Huaxiang Deng, Xiaodong Chen, Yueling Shang, Xiaochen Liu, Xiaohong Yu. (2022) Efficient whole cell biotransformation of tyrosol from L-tyrosine by engineered Escherichia coli. ENZYME AND MICROBIAL TECHNOLOGY, [PMID:35872508] [10.1016/j.enzmictec.2022.110100] |
| 6. Li Jiang, Yanling Xiong, Yu Tu, Wentong Zhang, Qiyun Zhang, Peng Nie, Xiaojun Yan, Hongning Liu, Ronghua Liu, Guoliang Xu. (2022) Elucidation of the Transport Mechanism of Puerarin and Gastrodin and Their Interaction on the Absorption in a Caco-2 Cell Monolayer Model. MOLECULES, 27 (4): (1230). [PMID:35209020] [10.3390/molecules27041230] |
| 7. Xu Yu, Li Yu, Fei Ma, Peiwu Li. (2020) Quantification of phenolic compounds in vegetable oils by mixed-mode solid-phase extraction isotope chemical labeling coupled with UHPLC-MS/MS. FOOD CHEMISTRY, [PMID:32721834] [10.1016/j.foodchem.2020.127572] |
| 8. Wenjing Li, Congyong Sun, Wenwen Deng, Yingkun Liu, Michael Adu-Frimpong, Jiangnan Yu, Ximing Xu. (2019) Pharmacokinetic of gastrodigenin rhamnopyranoside from Moringa seeds in rodents. FITOTERAPIA, [PMID:31470062] [10.1016/j.fitote.2019.104348] |
| 9. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu. (2019) Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis. Journal of Ginseng Research, [PMID:32148411] [10.1016/j.jgr.2019.01.001] |
| 10. Zhihua Liao, Fei Qiu, Junlan Zeng, Li Gu, Bangjun Wang, Xiaozhong Lan, Min Chen. (2018) A Novel UDP-Glycosyltransferase of Rhodiola crenulata Converts Tyrosol to Specifically Produce Icariside D2. Biomed Research International, [PMID:30027099] [10.1155/2018/7970590] |
| 11. Xianglai Li, Zhenya Chen, Yifei Wu, Yajun Yan, Xinxiao Sun, Qipeng Yuan. (2018) Establishing an Artificial Pathway for Efficient Biosynthesis of Hydroxytyrosol. ACS Synthetic Biology, [PMID:29281883] [10.1021/acssynbio.7b00385] |
| 12. Zhihong Wang, Chengzhang Wang, Changwei Zhang, Wenjun Li. (2017) Ultrasound-assisted enzyme catalyzed hydrolysis of olive waste and recovery of antioxidant phenolic compounds. Innovative Food Science & Emerging Technologies, [PMID:] [10.1016/j.ifset.2017.02.013] |
| 13. Zhuang Yibin, Jiang Jingjie, Bi Huiping, Yin Hua, Liu Shaowei, Liu Tao. (2015) Synthesis of rosmarinic acid analogues in Escherichia coli. BIOTECHNOLOGY LETTERS, 38 (4): (619-627). [PMID:26667131] [10.1007/s10529-015-2011-1] |
| 14. Yanhong BI, Zhaoyu WANG, Yanyong MAO, Shangyong ZHENG, Haijiang ZHANG, Hao SHI. (2012) Ionic Liquid Effects on the Activity of β-Glycosidase for the Synthesis of Salidroside in Co-solvent Systems. CHINESE JOURNAL OF CATALYSIS, [PMID:] [10.1016/S1872-2067(11)60395-1] |
| 15. Yuqi Liu, Li Yuan, Guozheng Liang, Aijuan Gu. (2024) Preparation of Thermally Resistant and Mechanically Strong Biomass Benzoxazine Resins via Green Strategy. ACS Sustainable Chemistry & Engineering, [PMID:] [10.1021/acssuschemeng.3c06195] |
| 16. Jishan Li, Muyang Li, Chenyu Yong, Zhemin Zhou, Laichuang Han, Zhongmei Liu. (2025) Reshaping UDP-binding pocket of bacterial sucrose synthase to improve efficiency of UDP-glucose production. BIORESOURCE TECHNOLOGY, [PMID:40090494] [10.1016/j.biortech.2025.132396] |
| 17. Yu Peng, Xiaoao Xiao, Tingting Ji, Xinyuan Wang, Yixuan Xu, Jianbo Xiao, Hui Cao, Zhiyong Chen, Huifan Liu, Yuanqing Gao, Hongxun Tao. (2024) Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics. Food Science and Human Wellness, [PMID:] [10.26599/FSHW.2022.9250176] |
| 18. Feng Lijuan, Yu Shuping, Jin Weimei, Xiao Changyan, Qiao Yan, Yang Guangfeng. (2024) The role of hydroponic solution of Ulva fasciata in modulating the antibiotic resistance of Vibrio alginolyticus. JOURNAL OF APPLIED MICROBIOLOGY, [PMID:39533112] [10.1093/jambio/lxae281] |
| 19. Tong Sun, Jingyi Yang, Lili Lu. (2025) Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects. Current Research in Food Science, [PMID:41080798] [10.1016/j.crfs.2025.101206] |
| 20. Siwen Li, Hongyan Zhu, Songtao Li, Rasmané SEMDE, Hongbo Teng, Mengqi Shi, Liang Huang, Xinru Lou, Beining Jia, Yan Zhao. (2025) Protocatechuic Acid improves Alzheimer's disease by regulating the cholinergic synaptic signaling pathway. CHEMISTRY & BIODIVERSITY, [PMID:39776239] [10.1002/cbdv.202402771] |
| 21. Zhiyun Yang, Xiao Ding, Junbo Yang, Mehboob Hussain, Yanan Ruan, Xi Gao, Guoxing Wu. (2025) Phytotoxic Potential of Methyl 4-Hydroxyphenylacetate Against Ageratina adenophora (Spreng.): Mechanistic Insights and Implications for Sustainable Weed Management. Agriculture-Basel, 15 (8): [PMID:] [10.3390/agriculture15080824] |
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