5,6-Dimethylbenzimidazole - ≥99% , CAS No.582-60-5

CAS: 582-60-5 Cat. No.: D109360 Molecular Weight: 146.19 Beilstein Registry Number: 116595 EC Number: 209-488-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
5,6-DIMETHYLBENZIMIDAZOLE [MI] | Dimedazol | D1345 | Q15269676 | 5,6-dimethyl-1H-1,3-benzodiazole | 5,6-dimethyl-1H-benzoimidazole | 5,6-Dimethylbenzimidazole, purum, >=99.0% (NT) | AS-10901 | AKOS000121551 | MFCD00005603 | 5,6-Dimethyl-1H-benzimidazole |
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
D109360-5g
8
$9.90
10g
D109360-10g
1
$12.90
25g
D109360-25g
8
$14.90
100g
D109360-100g
1
$49.90
500g
D109360-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

5,6-Dimethyl-1H-benzo[d]imidazole is an endogenous metabolite. 5,6-Dimethyl-1H-benzo[d]imidazole is also a benzimidazole derivative and can be used in the synthesis of other active compounds.

Specifications

Synonyms
5, 6-DIMETHYLBENZIMIDAZOLE [MI] | Dimedazol | D1345 | Q15269676 | 5, 6-dimethyl-1H-1, 3-benzodiazole | 5, 6-dimethyl-1H-benzoimidazole | 5, 6-Dimethylbenzimidazole, purum, >=99.0% (NT) | AS-10901 | AKOS000121551 | MFCD00005603 | 5, 6-Dimethyl-1H-benzimidazole |
Specifications & Purity
≥99%
Storage
Room temperature
Shipped In
Normal
Purity
≥99%
Names and Identifiers
Pubchem Sid488179539
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179539
Canonical SmilesCC1=CC2=C(C=C1C)N=CN2
IUPAC Name5,6-dimethyl-1H-benzimidazole
InChIKeyLJUQGASMPRMWIW-UHFFFAOYSA-N
INCHI1S/C9H10N2/c1-6-3-8-9(4-7(6)2)11-5-10-8/h3-5H,1-2H3,(H,10,11)
Isomeric SMILES CC1=CC2=C(C=C1C)N=CN2
WGK Germany 3
RTECS DD8280000
Molecular Weight 146.19
Beilstein 116595
Reaxy-Rn 116595
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=116595&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassBenzimidazoles
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzimidazoles
Alternative Parents Benzenoids  Imidazoles  Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzimidazole - Benzenoid - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds).
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SR (39847 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Cyp2b1 Cytochrome P450 2B1 (145 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
L2508593Certificate of AnalysisNov 22, 2025 D109360
L2508599Certificate of AnalysisNov 22, 2025 D109360
L2508600Certificate of AnalysisNov 22, 2025 D109360
G2130130Certificate of AnalysisMay 12, 2025 D109360
G2130131Certificate of AnalysisMay 12, 2025 D109360
G2130177Certificate of AnalysisMay 12, 2025 D109360
D2314176Certificate of AnalysisDec 03, 2022 D109360
D2314249Certificate of AnalysisDec 03, 2022 D109360
D2314267Certificate of AnalysisDec 03, 2022 D109360
D2314268Certificate of AnalysisDec 03, 2022 D109360
D2314270Certificate of AnalysisDec 03, 2022 D109360
D2314370Certificate of AnalysisDec 03, 2022 D109360
F2403385Certificate of AnalysisDec 03, 2022 D109360
F2510213Certificate of AnalysisDec 03, 2022 D109360
G2325028Certificate of AnalysisMar 22, 2021 D109360

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Chemical and Physical Properties
SolubilitySoluble in ethanol (50 mg/ml).
Melt Point(°C)203-206°C
Molecular Weight146.190 g/mol
XLogP32.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass146.084 Da
Monoisotopic Mass146.084 Da
Topological Polar Surface Area28.700 Ų
Heavy Atom Count11
Formal Charge0
Complexity146.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Huimin Yang, Xin Liu, Jihui Wang, Wenbin Hu.  (2023)  Preparation and Corrosion Resistance of ZIF-8-(5, 6-dimethylbenzimidazole)/LDHs Composite Film on Magnesium Alloy.  International Journal of Electrochemical Science,      [PMID:] [10.20964/2020.12.73]
2. Summaira Saghir, Yongqiang Wang, Zhenggang Xiao.  (2023)  In situ synthesis of multivariant zeolitic tetrazolate imidazole frameworks (ZTIFs) with uncoordinated N-heteroatom sites for efficient adsorption of antiviral drugs.  Journal of Cleaner Production,      [PMID:37304129] [10.1016/j.jclepro.2023.137654]
3. Yun Xiong, Yifan Shu, Niyan Deng, Xiaogang Luo, Shengpeng Liu, Xiaoyu Wu.  (2024)  A Novel Modified ZIF-8 Nanoparticle with Enhanced Interfacial Compatibility and Pervaporation Performance in a Mixed Matrix Membrane for De-Alcoholization in Low-Concentration Solutions.  MOLECULES,  29  (18): (4465).  [PMID:39339460] [10.3390/molecules29184465]
4. Huaiyin Chen, Zhonghe Wang, Jun Li, Xiaolin Liu, Congxiang Li, Yongzhao Li, Weihe Yu, Longmin Liu, Yi Zhang, Yuekun Lai, Weilong Cai.  (2025)  Facile preparation of highly hydrophobic ZIF-8/DMBIM modified epoxy coatings with enhanced acid, alkali and marine corrosion resistance.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2025.102512]
5. Meng Zhu, Lingrui Zhang, Hong Ma, Ruiying Zhu, Yating Tan, Rui Wang, Xiaobo Gong, Yong Liu.  (2024)  Janus stainless steel mesh-based membrane with asymmetric wettability for highly efficient gravity-driven oil-water emulsion separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.122801]
6. Le Zhong, Zhongjie Wang, Xiaohong Ye, Jiandong Cui, Ziyuan Wang, Shiru Jia.  (2024)  Molecular simulations guide immobilization of lipase on nest-like ZIFs with regulatable hydrophilic/hydrophobic surface.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:38636222] [10.1016/j.jcis.2024.04.075]
Solution Calculators
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