5-Sulfosalicylic acid hydrate - ≥95% , CAS No.304851-84-1

CAS: 304851-84-1 Cat. No.: S467234 Molecular Weight: 218.18 (anhydrous basis) EC Number: 684-226-0 PubChem CID: 665025
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
J-017979 | 5-Sulfosalicylic acid hydrate | AS-67604 | SMR000046135 | 5-SULFOSALICYLIC ACID HYDRATE 95 | MLS000084589 | 2-hydroxy-5-sulfobenzoic acid;hydrate | D95905 | HMS2289M10 | DTXSID80349828 | 5-Sulfosalicylic acid hydrate, 95% | Benzoic acid, 2-hyd
Storage
Protected from light,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100g
S467234-100g
2

$85.90

$105.90
Save $20.00 (18.89%)
500g
S467234-500g
2

$256.90

$473.90
Save $217.00 (45.79%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Description

5-Sulfosalicylic acid hydrate can be used in the synthesis of hydrated complexes with benzotriazole,N, N′-dimethylpiperazine andN-methylpiperazine for the study of hydrogen bonding in supramolecular crystal structure.

Specifications

Synonyms
J-017979 | 5-Sulfosalicylic acid hydrate | AS-67604 | SMR000046135 | 5-SULFOSALICYLIC ACID HYDRATE 95 | MLS000084589 | 2-hydroxy-5-sulfobenzoic acid;hydrate | D95905 | HMS2289M10 | DTXSID80349828 | 5-Sulfosalicylic acid hydrate, 95% | Benzoic acid, 2-hyd
Specifications & Purity
≥95%
Storage
Protected from light, Room temperature
Shipped In
Normal
Purity
≥95%
Names and Identifiers
Pubchem Sid504759800
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504759800
Canonical SmilesC1=CC(=C(C=C1S(=O)(=O)O)C(=O)O)O.O
IUPAC Name2-hydroxy-5-sulfobenzoic acid;hydrate
InChIKeyPAUDQWJTTVPGHZ-UHFFFAOYSA-N
INCHI1S/C7H6O6S.H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;/h1-3,8H,(H,9,10)(H,11,12,13);1H2
Isomeric SMILES C1=CC(=C(C=C1S(=O)(=O)O)C(=O)O)O.O
WGK Germany 3
PubChem CID 665025
Molecular Weight 218.18 (anhydrous basis)

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzenesulfonic acids and derivatives
Intermediate Tree Nodes Sulfobenzoic acids
Direct Parent3-sulfobenzoic acids
Alternative Parents Sulfosalicylic acids and derivatives  Salicylic acids  Benzoic acids  Benzenesulfonyl compounds  1-sulfo,2-unsubstituted aromatic compounds  Benzoyl derivatives  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Sulfonyls  Organosulfonic acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents 3-sulfobenzoic acid - Sulfosalicylic acid or derivatives - Hydroxybenzoic acid - Salicylic acid or derivatives - Salicylic acid - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - Benzoic acid or derivatives - Benzoic acid - Arylsulfonic acid or derivatives - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Vinylogous acid - Sulfonyl - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organosulfur compound - Organic oxide - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 3-sulfobenzoic acids. These are sulfobenzoic acid carrying the sulfonyl group at the 3-position of the benzene group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
E23181004Certificate of AnalysisMar 10, 2026 S467234
E23181007Certificate of AnalysisMar 10, 2026 S467234
E2318692Certificate of AnalysisMar 10, 2026 S467234
Chemical and Physical Properties
SensitivityLight sensitive
Molecular Weight236.200 g/mol
XLogP3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass235.999 Da
Monoisotopic Mass235.999 Da
Topological Polar Surface Area121.000 Ų
Heavy Atom Count15
Formal Charge0
Complexity316.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Citations of This Product
References
1. Boyu Du, Yumeng Wang, Qian Zheng, Xing Wang, Xiaohong Chen, Jinghui Zhou, Guihua Yang, Run-Cang Sun.  (2023)  A novel modified lignin-based adsorbent for removal of malachite green and Pb2+ ions from wastewater.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.125495]
2. Dingqiang Liang, Ziyang Chang, Yanguang Chen, Jianbin Chen, Huifang Zhao, Lizheng Sha, Daliang Guo.  (2023)  High mass loading paper-based electrode material with cellulose fibers under coordination of zirconium oxyhydroxide nanoparticles and sulfosalicylic acid.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37327930] [10.1016/j.ijbiomac.2023.125414]
3. Longjun Guo, Wei Liu, Chunqing Wang.  (2023)  Twistable and tailorable Cu-doped SnO2@PANI textile for wearable ammonia sensing.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2023.157529]
4. Xingyu Chen, Yifu Zhang, Chen Wang, Xueying Dong, Changgong Meng.  (2021)  The synthesis and electrochemical properties of low-crystallinity iron silicate derived from reed leaves as a supercapacitor electrode material.  DALTON TRANSACTIONS,  50  (25): (8917-8926).  [PMID:34106113] [10.1039/D1DT01190A]
5. Luyu Yang, Xuran Xu, Mengdi Liu, Chen Chen, Jian Cui, Xiao Chen, Kai Wu, Dongping Sun.  (2021)  Wearable and flexible bacterial cellulose/polyaniline ammonia sensor based on a synergistic doping strategy.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.129647]
6. Youchao Teng, Jing Wei, Hongbiao Du, Mansoorianfar Mojtaba, Dagang Li.  (2020)  A solar and thermal multi-sensing microfiber supercapacitor with intelligent self-conditioned capacitance and body temperature monitoring.  Journal of Materials Chemistry A,  (23): (11695-11711).  [PMID:] [10.1039/D0TA02894K]
7. Qi Shen, Minjuan Zuo, Li Ma, Ye Tian, Lu Wang, Huidi Jiang, Quan Zhou, Hui Zhou, Lushan Yu, Su Zeng.  (2014)  Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:25451576] [10.1016/j.cbi.2014.10.014]
8. Jiahua Yan, Zhongxiao Du, Zijian Yu, Bing Cao, ThiThi Mar, Dujian Qin, Rui Zhang.  (2024)  Optimization of mass transfer-enhanced chlorine-resistant crosslinked PVA composite membranes for pervaporation desalination.  DESALINATION,      [PMID:] [10.1016/j.desal.2024.117872]
9. Zixuan Pu, Manjun Guan, Guilong Wang, Kuan Li, Mingtian Li.  (2025)  One-Step Microwave Solid-State Synthesis of N, S Co-Doped Carbon Dots and Their Multifunctional Applications.  LUMINESCENCE,  40  (8): (e70271).  [PMID:40746282] [10.1002/bio.70271]
10. Yuandong Yu, Guizhao Liang.  (2021)  Interaction mechanism of phenolic acids and zein: A spectrofluorometric and molecular dynamics investigation.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2021.118032]
11. Mengqi Jian, Zongmao Lv, Runfeng Zhang, Jie Liu, Xuejing Zheng, Jun Zhang, Keyong Tang.  (2025)  Low-temperature assisted in-situ layer-by-layer polymerization of polyaniline/cellulose fibers with high strength and conductivity for sensing multiple signals.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163446]
12. Jie Song, Yi Mu, Shuang Yu.  (2026)  Mechanism-Driven Development of Dual-Acid Doped Poly(butylene succinate) Composites for Flexible Sensors with Integrated High Conductivity and Biodegradability.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.5c04269]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.