AGL-2263 - 10mM in DMSO , CAS No.638213-98-6

CAS: 638213-98-6 Cat. No.: A656154 Molecular Weight: 322.27 PubChem CID: 9818584

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor

In Vitro

AGL-2263 (5 μM, for 1 h followed by insulin treatment for 24 h) inhibits IR and insulin could still induce phosphorylation of AKT and ERK1/2 after the IR inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: Granulosa cells. Concentration: 5 μM. Incubation Time: For 1 h followed by insulin treatment for 24 h. Result: Insulin still induced phosphorylation of AKT and ERK1/2 after IR was inhibited by AGL2263.

IC50& Target:Insulin receptor

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: C1=CC2=C(C=C1/C=C(\C#N)/C(=O)C3=CC(=C(C=C3)O)O)NC(=O)O2
• PubChem CID: 9818584
• MeSH Entry Terms: AGL 2263;AGL-2263;AGL2263
• Molecular Weight: 322.27