AMPA Receptors - ≥98%(HPLC) , CAS No.875927-64-3

CAS: 875927-64-3 Cat. No.: U288277 Molecular Weight: 334.41
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
U288277-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$95.90
5mg
U288277-5mg
4
$339.90
10mg
U288277-10mg
3
$559.90
25mg
U288277-25mg
3
$1,199.90
50mg
U288277-50mg
2
$2,199.90
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Positive allosteric modulator of AMPA receptors (pEC50= 5.2 for potentiation of AMPA-mediated currentsin vitro). Also potentiates AMPA-mediated synaptic responsesin vivo. Improves performance of rats in various learning and memory paradigms
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ACTIVATOR
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesCC(C)S(=O)(=O)NC1CC2=C(C1)C=C(C=C2)C3=CN=C(C=C3)F
IUPAC NameN-[(2R)-5-(6-fluoropyridin-3-yl)-2,3-dihydro-1H-inden-2-yl]propane-2-sulfonamide
InChIKeyQXQSUBKWSHMXDP-MRXNPFEDSA-N
INCHI1S/C17H19FN2O2S/c1-11(2)23(21,22)20-16-8-13-4-3-12(7-15(13)9-16)14-5-6-17(18)19-10-14/h3-7,10-11,16,20H,8-9H2,1-2H3/t16-/m1/s1
Isomeric SMILES CC(C)S(=O)(=O)N[C@@H]1CC2=C(C1)C=C(C=C2)C3=CN=C(C=C3)F
Molecular Weight 334.41
Reaxy-Rn 12503579
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12503579&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GRIA3 Tclin Glutamate receptor ionotropic, AMPA 3 (127 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIA1 Tclin Glutamate receptor ionotropic, AMPA 1 (277 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIA2 Tclin Glutamate receptor ionotropic, AMPA 2 (847 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
G2501523Certificate of AnalysisDec 24, 2024 U288277
G2501531Certificate of AnalysisDec 24, 2024 U288277
G2501532Certificate of AnalysisDec 24, 2024 U288277
G2501533Certificate of AnalysisDec 24, 2024 U288277
G2501534Certificate of AnalysisDec 24, 2024 U288277
G2501535Certificate of AnalysisDec 24, 2024 U288277
G2501536Certificate of AnalysisDec 24, 2024 U288277
G2501537Certificate of AnalysisDec 24, 2024 U288277
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 33.44, Max Conc. mM: 100
Solution Calculators
Reviews

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