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· · COA & SDS available for every product · Same-day shipping on in-stock items ARRY-520 - ≥98% , Kinesin-like protein 1 inhibitor, CAS No.885060-09-3, Kinesin-like protein 1 inhibitor
Synonyms
EX-A678 | (S)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide. | Arry520 | ARRY-520 | GLYFIX CS 50 | 8A49OSO368 | Filanesib (USAN/INN) | BCP07442 | D11754 | J-519598 | Filanesib [INN] | Filanesib [U
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
EX-A678 | (S)-2-(3-aminopropyl)-5-(2, 5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1, 3, 4-thiadiazole-3(2H)-carboxamide. | Arry520 | ARRY-520 | GLYFIX CS 50 | 8A49OSO368 | Filanesib (USAN/INN) | BCP07442 | D11754 | J-519598 | Filanesib [INN] | Filanesib [U
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
ARRY-520 is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 had low nanomolar antiproliferative activity in tumor cell lines. KSP inhibitor ARRY-520 specifically inh
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Kinesin-like protein 1 inhibitor
Product Properties Names and Identifiers Pubchem Sid 504770317 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504770317 Canonical Smiles CN(C(=O)N1C(SC(=N1)C2=C(C=CC(=C2)F)F)(CCCN)C3=CC=CC=C3)OC IUPAC Name (2S)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3-carboxamide InChIKey LLXISKGBWFTGEI-FQEVSTJZSA-N INCHI 1S/C20H22F2N4O2S/c1-25(28-2)19(27)26-20(11-6-12-23,14-7-4-3-5-8-14)29-18(24-26)16-13-15(21)9-10-17(16)22/h3-5,7-10,13H,6,11-12,23H2,1-2H3/t20-/m0/s1 Isomeric SMILES CN(C(=O)N1[C@](SC(=N1)C2=C(C=CC(=C2)F)F)(CCCN)C3=CC=CC=C3)OC Molecular Weight 420.48 Reaxy-Rn 12616142 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12616142&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Phenylbutylamines Intermediate Tree Nodes Not available Direct Parent Phenylbutylamines Alternative Parents Fluorobenzenes Aralkylamines Aryl fluorides Thiadiazolines Semicarbazides Azacyclic compounds Organofluorides Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Phenylbutylamine - Fluorobenzene - Halobenzene - Aralkylamine - Aryl fluoride - Aryl halide - Semicarbazide - Thiadiazoline - Azacycle - Organoheterocyclic compound - Amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Primary amine - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylbutylamines. These are compounds containing a phenylbutylamine moiety, which consists of a phenyl group substituted at the fourth carbon by an butan-1-amine. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO Molecular Weight 420.500 g/mol XLogP3 3.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 6 Exact Mass 420.143 Da Monoisotopic Mass 420.143 Da Topological Polar Surface Area 96.500 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 605.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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