Betaxolol - Moligand™, 10mM in DMSO , Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor, CAS No.63659-18-7, Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor

CAS: 63659-18-7 Cat. No.: B408774 Molecular Weight: 307.43 EC Number: 613-310-1
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
SL 75212 | 1-​[4-​[2-​(cyclopropylmethoxy)​ethyl]​phenoxy]​-​3-​[(1-​methylethyl)​amino]​-2-​propanol
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
B408774-1ml
2

$123.90

$179.90
Save $56.00 (31.13%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Betaxolol (SL 75212) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥96%

Specifications

Synonyms
SL 75212 | 1-​[4-​[2-​(cyclopropylmethoxy)​ethyl]​phenoxy]​-​3-​[(1-​methylethyl)​amino]​-2-​propanol
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Betaxolol (SL 75212) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ANTAGONIST
Mechanism of action
Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor
Names and Identifiers
Isomeric SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
Molecular Weight 307.43
Reaxy-Rn 1991268
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1991268&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
ADRB2 Tclin Beta-2 adrenergic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRB1 Tclin Beta-1 adrenergic receptor (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro      
Melt Point(°C)61-63°C
Citations of This Product
References
1. Wu Jia, Xiao Xue, Li Zhenqun, Jia Li.  (2019)  Enantioseparation of chiral β-blockers using polynorepinephrine-coated nanoparticles and chiral capillary electrophoresis.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  411  (10): (2121-2129).  [PMID:30734853] [10.1007/s00216-019-01641-4]
Solution Calculators
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