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BI 99179 - 10mM in DMSO , CAS No.1291779-76-4
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats
In Vitro
BI 99179 is potent in the mouse hypothalamic N-42 cell with an IC 50 of 0.6 μM. BI 99179 shows no significant LDH release in the cytotoxicity assay up to 30 μM. BI 99179 (BI-99179; 1, 2, and 4 µM) shows antiproliferative efficacy in human glioma GAMG cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: Human glioma GAMG cells Concentration: 1, 2, 4 µM Incubation Time: 96 to 120 hours Result: The optimal palmitate concentration for GAMG cell line was 4 µM.
In Vivo
BI 99179 has a super pharmacokinetic profile in male Han/Wistar rats (oral application of 4 mg/kg) with half life (t 1/2 ) of 3.0 h . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 79 nM (FASN)
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Isomeric SMILES | CCC(=O)N[C@H]1CC[C@H](C1)C(=O)N(C)C2=CC=C(C=C2)C3=NC4=CC=CC=C4O3 |
|---|---|
| PubChem CID | 51346964 |
| Molecular Weight | 391.46 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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