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· · COA & SDS available for every product · Same-day shipping on in-stock items (-)-Bicuculline methiodide - ≥99%(HPLC) , CAS No.40709-69-1
Synonyms
(+)-Bicuculline methiodide | (S)-6,6-dimethyl-5-((R)-8-oxo-6,8-dihydroisobenzofuro[5,4-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium iodide | AI3-50324 | DTXSID60873651 | HMS3414P11 | B-136 | HMS3678P09 | J-100046 | MLS000069
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Why this grade ≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
(+)-Bicuculline methiodide | (S)-6, 6-dimethyl-5-((R)-8-oxo-6, 8-dihydroisobenzofuro[5, 4-d][1, 3]dioxol-6-yl)-5, 6, 7, 8-tetrahydro-[1, 3]dioxolo[4, 5-g]isoquinolin-6-ium iodide | AI3-50324 | DTXSID60873651 | HMS3414P11 | B-136 | HMS3678P09 | J-100046 | MLS000069
Specifications & Purity
≥99%(HPLC)
Biochemical and Physiological Mechanisms
Methiodide form of classical GABAAreceptor antagonist(+)-bicuculline. More water-soluble and stable. Non-GABA receptor-mediated actions reported, including actions on calcium-dependent potassium channels.Methobromide SaltandMethochloride Saltalso availabl
Names and Identifiers Canonical Smiles C[N+]1(CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-] IUPAC Name (6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;iodide InChIKey HKJKCPKPSSVUHY-GRTNUQQKSA-M INCHI 1S/C21H20NO6.HI/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1 Isomeric SMILES C[N+]1(CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-] WGK Germany 3 PubChem CID 104871 Molecular Weight 509.3
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
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Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Alkaloids and derivatives Class Phthalide isoquinolines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Phthalide isoquinolines Alternative Parents Tetrahydroisoquinolines Phthalides Benzofuranones Benzodioxoles Aralkylamines Benzenoids Tetraalkylammonium salts Carboxylic acid esters Lactones Acetals Azacyclic compounds Oxacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic iodide salts Organic oxides Organopnictogen compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Phthalide isoquinoline - Benzofuranone - Phthalide - Isobenzofuranone - Tetrahydroisoquinoline - Benzodioxole - Isocoumaran - Aralkylamine - Benzenoid - Tetraalkylammonium salt - Quaternary ammonium salt - Carboxylic acid ester - Lactone - Organoheterocyclic compound - Azacycle - Oxacycle - Carboxylic acid derivative - Acetal - Monocarboxylic acid or derivatives - Organic iodide salt - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Amine - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Organic salt - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as phthalide isoquinolines. These are organic compounds with a structure characterized by an isoquinoline moiety linked to phthalide. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 10.19, Max Conc. mM: 20; Solvent:DMSO, Max Conc. mg/mL: 25.46, Max Conc. mM: 50 Molecular Weight 509.300 g/mol XLogP3 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 1 Exact Mass 509.034 Da Monoisotopic Mass 509.034 Da Topological Polar Surface Area 63.200 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 655.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
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