Biotin-maleimide - ≥95% , CAS No.116919-18-7

CAS: 116919-18-7 Cat. No.: B302263 Molecular Weight: 451.54
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
Biotin-maleimide | N'-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl]-6-(2,5-dioxopyrrol-1-yl)hexanehydrazide | BMHH | N-Biotinoyl-N'-(maleimidohexanoyl)hydrazine | N-Biotinoyl-N-(maleimidohexanoyl)hydrazine | N-生物素基-N′
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
B302263-10mg
2
$100.90
25mg
B302263-25mg
2
$185.90
100mg
B302263-100mg
1
$535.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Description

Biotin-Malay Metabolism is a biotin conversion thiol reagent used to biotiny different proteins through artificially induced or natural sulfhydryl groups. . Biotin-Malay metabolism can also be used to detect protein SH groups by the spot method.

Product Application

The 0.01 mg/ml biotin-maleic substituted PBS (containing 0.1% Tween 20) solution can be used to detect the deprotected cysteine ​​thiol present on the immobilized peptide after 1 hour in series.

Connect in series via effective thioether bonds. Usually used to connect to internal sulfhydryl groups, such as proteins, without changing primary amines.

Specifications

Synonyms
Biotin-maleimide | N'-[5-[(3aS, 4S, 6aR)-2-oxo-1, 3, 3a, 4, 6, 6a-hexahydrothieno[3, 4-d]imidazol-4-yl]pentanoyl]-6-(2, 5-dioxopyrrol-1-yl)hexanehydrazide | BMHH | N-Biotinoyl-N'-(maleimidohexanoyl)hydrazine | N-Biotinoyl-N-(maleimidohexanoyl)hydrazine | N-生物素基-N′
Specifications & Purity
≥95%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Pubchem Sid504757777
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504757777
Canonical SmilesC1C2C(C(S1)CCCCC(=O)NNC(=O)CCCCCN3C(=O)C=CC3=O)NC(=O)N2
IUPAC NameN'-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl]-6-(2,5-dioxopyrrol-1-yl)hexanehydrazide
InChIKeyVAPZWEFPQRDVHR-NJSLBKSFSA-N
INCHI1S/C20H29N5O5S/c26-15(7-2-1-5-11-25-17(28)9-10-18(25)29)23-24-16(27)8-4-3-6-14-19-13(12-31-14)21-20(30)22-19/h9-10,13-14,19H,1-8,11-12H2,(H,23,26)(H,24,27)(H2,21,22,30)/t13-,14-,19-/m0/s1
Isomeric SMILES C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NNC(=O)CCCCCN3C(=O)C=CC3=O)NC(=O)N2
Molecular Weight 451.54
Reaxy-Rn 40895108
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=40895108&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
I2301236Certificate of AnalysisJun 11, 2026 B302263
I2301239Certificate of AnalysisJun 11, 2026 B302263
I2301240Certificate of AnalysisJun 11, 2026 B302263
A2622155Certificate of AnalysisJun 19, 2024 B302263
G2424288Certificate of AnalysisJun 19, 2024 B302263
G2424289Certificate of AnalysisJun 19, 2024 B302263
I2301162Certificate of AnalysisAug 11, 2023 B302263
I2301237Certificate of AnalysisAug 11, 2023 B302263
I2301238Certificate of AnalysisAug 11, 2023 B302263
Chemical and Physical Properties
Solubilityacetic acid: 20 mg/mL
Molecular Weight451.500 g/mol
XLogP3-0.100
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Exact Mass451.189 Da
Monoisotopic Mass451.189 Da
Topological Polar Surface Area162.000 Ų
Heavy Atom Count31
Formal Charge0
Complexity740.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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