bpV(HOpic) - ≥95% , CAS No.722494-26-0

CAS: 722494-26-0 Cat. No.: B334661 Molecular Weight: 347.24 EC Number: 806-224-2 PubChem CID: 54692867
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Status
Price
Qty
5mg
B334661-5mg
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$145.90

$266.90
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10mg
B334661-10mg
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$264.90

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25mg
B334661-25mg
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$587.90

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50mg
B334661-50mg
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$1,059.90

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100mg
B334661-100mg
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$1,907.90

$3,503.90
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

bpV(HOpic) is a bisperoxo oxovanadate dipotassium salt coordinated to 5-hydroxypyridine-2-carboxylate. This vanadium compound has been shown to be a potent inhibitor of protein phosphotyrosine phosphatase (PTP) and PTEN, and has been described to act as an insulin mimetic. This compound has been shown to activate the insulin receptor kinase of hepatoma cells, stimulate lipogenesis in adipocytes, and to enhance PI3K/Akt signaling that could prevent ischemia-reperfusion (I/R) injury to the myocardium.

Specifications

Synonyms
Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1, κO2)oxodiperoxy-vanadate(2-), dipotassium
Specifications & Purity
≥95%
Biochemical and Physiological Mechanisms
bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Canonical Smiles[K]OC(=O)C1=CC=C(O)C=[N]1[V]23(O[K])(OO2)OO3
Isomeric SMILES C1=CC(=NC=C1[O-])C(=O)O.OO.OO.O=[V].[K+].[K+]
WGK Germany 3
PubChem CID 54692867
Molecular Weight 347.24

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySoluble in cold water (easily), and DMSO. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
SensitivityLight & Moisture sensitive
Solution Calculators
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