≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Chromeceptin is a cell-permeable benzochromene compound that blocks insulin-induced adipogenesis in 3T3-L1 cells (100% blockage at ≤ 20 ng/μl) and selectively suppresses IGF2- (insulin-like growth factor 2) dependent growth of HepG2 carcinoma cells (IC|50|= 29 nM). Chromeceptin has been shown to bind to MFP-2 (multifunctional protein-2) and activate STAT6-mediated gene expression, such as IGFBP-1 and SOCS-3, in HepG2 cells.
| Pubchem Sid | 504762464 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504762464 |
| Canonical Smiles | CN(C)C1=CC2=C(C=C1)C(C(=C(O2)N)C#N)C3=CC(=CC=C3)C(F)(F)F |
| IUPAC Name | 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile |
| InChIKey | GVINXTXGDDSXFQ-UHFFFAOYSA-N |
| INCHI | 1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3 |
| Isomeric SMILES | CN(C)C1=CC2=C(C=C1)C(C(=C(O2)N)C#N)C3=CC(=CC=C3)C(F)(F)F |
| WGK Germany | 3 |
| Molecular Weight | 359.35 |
| Reaxy-Rn | 11787426 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11787426&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Neoflavonoids |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Neoflavonoids |
| Alternative Parents | Trifluoromethylbenzenes 1-benzopyrans Dialkylarylamines Ketene acetals Oxacyclic compounds Nitriles Organofluorides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Neoflavonoid skeleton - Benzopyran - Trifluoromethylbenzene - 1-benzopyran - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Monocyclic benzene moiety - Benzenoid - Ketene acetal or derivatives - Tertiary amine - Nitrile - Carbonitrile - Oxacycle - Organoheterocyclic compound - Alkyl halide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Cyanide - Alkyl fluoride - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as neoflavonoids. These are compounds with a structure based on the 4-phenylchromene backbone. |
| External Descriptors | Not available |
| Solubility | Soluble in water (<2 mg/ml), DMSO (>20 mg/ml), and methanol (100 mg/ml). |
|---|---|
| Refractive Index | n20D1.61 (Predicted) |
| Boil Point(°C) | ~497.2° C at 760 mmHg (Predicted) |
| Melt Point(°C) | 189.05° C (Predicted) |
| Molecular Weight | 359.300 g/mol |
| XLogP3 | 4.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 359.125 Da |
| Monoisotopic Mass | 359.125 Da |
| Topological Polar Surface Area | 62.300 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 607.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
I2222603