Crisnatol - ≥99% , CAS No.96389-68-3

CAS: 96389-68-3 Cat. No.: C651446 Formule: C₂₃H₂₃NO₂ Poids moléculaire: 345.43 PubChem CID: 57062

QUALITÉ & PURETÉ ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Vue d’ensemble

Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts .

In Vitro

Crisnatol (1.3 μg/mL; 24-72 h) inhibits the replication of HepG2 cells, decreases cell viability by 35%. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HepG2 cells Concentration: 1.3 μg/mL Incubation Time: 24 hours, 48 hours, 72 hours, and 126 hours Result: Inhibited cell viability at 48 hr.

In Vivo

Crisnatol (25 mg/kg; p.o.; single dose) shows oral activity and shows stable metabolite profile extract of rat feces by autoradiography. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Spécifications

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts

Conditions de stockage de stockage

Store at 2-8°C,Protected from light,Desiccated

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

Isomères SMILES

CC(CO)(CO)NCC1=CC2=C(C=CC3=CC=CC=C32)C4=CC=CC=C41

PubChem CID

57062

Poids moléculaire

345.43

Cibles associées (non humaines)

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO : 100 mg/mL (289.49 mM; Need ultrasonic)
• Poids moléculaire: 345.400 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 345.173 Da
• Monoisotopic Mass: 345.173 Da
• Topological Polar Surface Area: 52.500 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 463.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1