Deferiprone - Moligand™, 10 mM in DMSO , CAS No.30652-11-0

CAS: 30652-11-0 Cat. No.: D1499381 Molecular Weight: 139.15 Beilstein Registry Number: 21(5)12,114 EC Number: 629-275-0
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
D1499381-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$58.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer , cardiovascular disease , infection , inflammation, and neurological disease study .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Product Properties
ALogP0.5
Names and Identifiers
Isomeric SMILES CC1=C(C(=O)C=CN1C)O
WGK Germany 3
RTECS UU7785940
Molecular Weight 139.15
Beilstein 21(5)12,114
Reaxy-Rn 1447108
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1447108&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)272-275°C
Documents & Articles
Citations of This Product
References
1. Jiajia Luo, Yao Li, Yaru Li, Xuefei Chen, Panyu Du, Zheng Wang, Aixian Tian, Yanjun Zhao.  (2023)  Reversing Ferroptosis Resistance in Breast Cancer via Tailored Lipid and Iron Presentation.  ACS Nano,      [PMID:38055669] [10.1021/acsnano.3c08485]
2. Tiantian Chen, Yan Qin, Yao Li, Yaru Li, Jiajia Luo, Lanlan Fan, Meiyu Feng, Zheng Wang, Yanjun Zhao.  (2023)  Chiral Polymer Micelles Alleviate Adriamycin Cardiotoxicity via Iron Chelation and Ferroptosis Inhibition.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202300689]
3. Li Xie, Wenjie Chen, Qifang Chen, Yang Jiang, Erqun Song, Xiaokang Zhu, Yang Song.  (2022)  Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory.  Materials Today Bio,      [PMID:35865409] [10.1016/j.mtbio.2022.100353]
4. Lidong Yu, Mingyue He, Sihan Liu, Xinyue Dou, Li Li, Ning Gu, Bingsheng Li, Zhiguo Liu, Guixue Wang, Jianglin Fan.  (2021)  Fluorescent Egg White-Based Carbon Dots as a High-Sensitivity Iron Chelator for the Therapy of Nonalcoholic Fatty Liver Disease by Iron Overload in Zebrafish.  ACS Applied Materials & Interfaces,      [PMID:34756030] [10.1021/acsami.1c14674]
5. Zhou Qiao-Mei, Lu Yuan-Fei, Zhou Jia-Ping, Yang Xiao-Yan, Wang Xiao-Jie, Yu Jie-Ni, Du Yong-Zhong, Yu Ri-Sheng.  (2021)  Self-amplification of oxidative stress with tumour microenvironment-activatable iron-doped nanoplatform for targeting hepatocellular carcinoma synergistic cascade therapy and diagnosis.  JOURNAL OF NANOBIOTECHNOLOGY,  19  (1): (1-18).  [PMID:34749740] [10.1186/s12951-021-01102-0]
6. Xiaojiao Zheng, Xu Wang, Zifang Ding, Wei Li, Ying Peng, Jiang Zheng.  (2021)  Metabolic activation of deferiprone mediated by CYP2A6.  XENOBIOTICA,      [PMID:34006188] [10.1080/00498254.2021.1931729]
7. Wendi Han, Chenfang Miao, Xintian Zhang, Yinning Lin, Xiaoli Hao, Zhengjun Huang, Shaohuang Weng, Xinhua Lin, Xianzhong Guo, Jianyong Huang.  (2021)  A signal-off fluorescent strategy for deferasirox effective detection using carbon dots as probe and Cu2+ as medium.  ANALYTICA CHIMICA ACTA,      [PMID:34535261] [10.1016/j.aca.2021.338853]
8. Xueyang Jin, Ming Zhang, Jinghui Lu, Ximeng Duan, Jinyao Chen, Yue Liu, Wenqiang Chang, Hongxiang Lou.  (2021)  Hinokitiol chelates intracellular iron to retard fungal growth by disturbing mitochondrial respiration.  Journal of Advanced Research,      [PMID:35024181] [10.1016/j.jare.2021.06.016]
9. Qiongtao Song, Ying Zhao, Yanrong Yang, Xue Han, Junguo Duan.  (2020)  Astragaloside IV protects against retinal iron overload toxicity through iron regulation and the inhibition of MAPKs and NF-κB activation.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:33285147] [10.1016/j.taap.2020.115361]
10. Xiaokang Zhu, Li Xie, Jinming Tian, Yang Jiang, Erqun Song, Yang Song.  (2024)  A multi-mode Rhein-based nano-platform synergizing ferrotherapy/chemotherapy-induced immunotherapy for enhanced tumor therapy.  Acta Biomaterialia,      [PMID:38570106] [10.1016/j.actbio.2024.03.030]
11. Juanlong Li, Yezi Hu, Zewen Shen, Huihui Jin, Rong He, Wenkun Zhu, Guixia Zhao, Zhuoyu Ji, Bin Ma, Xiangke Wang.  (2024)  Efficient uranium(VI) recovery from fluorinated wastewater via deferiprone ligand complexation.  WATER RESEARCH,      [PMID:39631159] [10.1016/j.watres.2024.122884]
12. Yaru Li, Qian Yang, Lanlan Fan, Fang Liu, Yaqi Shang, Baoxin Zhang, Zheng Wang, Yanjun Zhao.  (2024)  Engineering synergistic liposomes against ovarian cancer via concurrent targeting of myeloid cell leukemia-1(MCL-1) and glutamate-cystine antiporter (SLC7A11).  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2024.106358]
13. Lintao Li, Runtian Li, Ruohan Guo, Shuang Guo, Xuan Qiao, Xinru Wu, Peng Han, Yunbo Sun, Xiaoxia Zhu, Zhuona Wu, Hui Gan, Zhiyun Meng, Guifang Dou, Ruolan Gu, Shuchen Liu.  (2024)  Preparation and Evaluation of a Combination of Chelating Agents for the Removal of Inhaled Uranium.  MOLECULES,  29  (23): (5759).  [PMID:39683918] [10.3390/molecules29235759]
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