Deoxypodophyllotoxin - Moligand™, ≥99% , CAS No.19186-35-7

Name: Deoxypodophyllotoxin - Moligand™, ≥99% , CAS No.19186-35-7
Brand: Aladdin Scientific
SKU: D651721
Availability: InStock

CAS: 19186-35-7 Cat. No.: D651721 Molecular Weight: 398.41 PubChem CID: 345501

COA

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Deoxypodophyllotoxin - Moligand™, ≥99% CAS No(19186-35-7) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Deoxypodophyllotoxin (intravenously injected; 5, 10, and 20 mg/kg; 3 times a week; 28 days) suppresses the tumors in a dose-dependent manner, the growth of tumors is inhibited by 22.19%, 47.91% and 50.93% with DPT at 5, 10 and 20 mg/kg, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Xenograft model of gastric cancer in nude mice with SGC-7901 cells Dosage: 5, 10, and 20 mg/kg Administration: Intravenously injected; 5, 10, and 20 mg/kg; 3 times a week; 28 days Result: Inhibited the growth of gastric cancer tumors.

Specifications

Synonyms

AC-34638 | Anthricin | F82121 | (5R, 5aR, 8aR)-5-(3, 4, 5-trimethoxyphenyl)-5, 8, 8a, 9-tetrahydrofuro[3', 4':6, 7]naphtho[2, 3-d][1, 3]dioxol-6(5aH)-one | (-)-Anthricin | 5, 8, 8a, 9, -Tetrahydro-5-(3, 4, 5-trimethoxyphenyl)furo[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)

Specifications & Purity

Moligand™, ≥99%

Biochemical and Physiological Mechanisms

Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥99%

Names and Identifiers

Canonical Smiles	COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O
IUPAC Name	(5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one
InChIKey	ZGLXUQQMLLIKAN-SVIJTADQSA-N
INCHI	1S/C22H22O7/c1-24-17-6-12(7-18(25-2)21(17)26-3)19-14-8-16-15(28-10-29-16)5-11(14)4-13-9-27-22(23)20(13)19/h5-8,13,19-20H,4,9-10H2,1-3H3/t13-,19+,20-/m0/s1
Isomeric SMILES	COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@@H](CC4=CC5=C(C=C24)OCO5)COC3=O
PubChem CID	345501
Molecular Weight	398.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lignans, neolignans and related compounds
  - Class Lignan lactones

Kingdom	Organic compounds
Superclass	Lignans, neolignans and related compounds
Class	Lignan lactones
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Lignan lactones
Alternative Parents	Aryltetralin lignans Furanonaphthodioxoles Tetralins Benzodioxoles Phenoxy compounds Anisoles Methoxybenzenes Alkyl aryl ethers Gamma butyrolactones Tetrahydrofurans Carboxylic acid esters Monocarboxylic acids and derivatives Oxacyclic compounds Acetals Hydrocarbon derivatives Carbonyl compounds Organic oxides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Lignan lactone - 1-aryltetralin lignan - Linear furanonaphthodioxole - Naphthofuran - Tetralin - Benzodioxole - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Gamma butyrolactone - Benzenoid - Tetrahydrofuran - Lactone - Carboxylic acid ester - Acetal - Oxacycle - Carboxylic acid derivative - Organoheterocyclic compound - Ether - Monocarboxylic acid or derivatives - Carbonyl group - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as lignan lactones. These are lignans that contain a lactone moiety. They include 1-aryltetralin lactones, dibenzylbutyrolactone lignans, and podophyllotoxins, among others.
External Descriptors	Lignans
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

ODC1 Tclin Ornithine decarboxylase (70 Activities)

Discover Target: ODC1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Date	Item
E2530342	Certificate of Analysis	Nov 04, 2024	D651721
E2530343	Certificate of Analysis	Nov 04, 2024	D651721
E2530345	Certificate of Analysis	Nov 04, 2024	D651721
E2530346	Certificate of Analysis	Nov 04, 2024	D651721
E2530347	Certificate of Analysis	Nov 04, 2024	D651721
E2530354	Certificate of Analysis	Nov 04, 2024	D651721
E2530367	Certificate of Analysis	Nov 04, 2024	D651721

Solubility	DMSO : 100 mg/mL (251.00 mM; Need ultrasonic)
Molecular Weight	398.400 g/mol
XLogP3	3.100
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Exact Mass	398.137 Da
Monoisotopic Mass	398.137 Da
Topological Polar Surface Area	72.500 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	598.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Deoxypodophyllotoxin - Moligand™, ≥99% , CAS No.19186-35-7

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

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