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Why this grade
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295 nm. Antithrombotic efficacy.
In Vitro
PAI-749 is a potent and selective synthetic antagonist of plasminogen activator inhibitor 1 (PAI-1) that preserved tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) activities in the presence of PAI-1 (IC 50 values, 157 and 87 nM, respectively). PAI-749 quenches the fluorescence (Fl) of fluorophore-tagged PAI-1 (PAI-NBD119) with the apparent K d of 254 nM) and the IC 50 of 140 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Synonyms
PAI-749
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 ( PAI-1 ) inhibitor with IC 50 of 295u2003nm. Antithrombotic efficacy.
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
| Pubchem Sid | 528764287 |
|---|---|
| Isomeric SMILES | CCCCCC1=C(N(C2=CC=CC=C21)CC3=CC=CC=C3)C4=CC5=C(C=C4)C=C(C=C5)OCC6=NNN=N6 |
| PubChem CID | 6450820 |
| Molecular Weight | 501.62 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2517256 | Certificate of Analysis | Feb 07, 2025 | D650860 |
| G2517257 | Certificate of Analysis | Feb 07, 2025 | D650860 |
| G2517258 | Certificate of Analysis | Feb 07, 2025 | D650860 |
| G2517259 | Certificate of Analysis | Feb 07, 2025 | D650860 |
| G2517260 | Certificate of Analysis | Feb 07, 2025 | D650860 |
| G2517261 | Certificate of Analysis | Feb 07, 2025 | D650860 |
Chemical and Physical Properties
| Solubility | DMSO : 125 mg/mL (249.19 mM; Need ultrasonic) |
|---|---|
| Sensitivity | Light sensitive，Moisture sensitive. |
| Molecular Weight | 501.600 g/mol |
| XLogP3 | 8.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 10 |
| Exact Mass | 501.253 Da |
| Monoisotopic Mass | 501.253 Da |
| Topological Polar Surface Area | 68.600 Ų |
| Heavy Atom Count | 38 |
| Formal Charge | 0 |
| Complexity | 716.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Solution Calculators
Reviews
Customer Reviews
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