DL-Methionine - ≥99% , CAS No.59-51-8

CAS: 59-51-8 Cat. No.: M104886 Molecular Weight: 149.21 Beilstein Registry Number: 636185 EC Number: 200-432-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
DL-2-Amino-4-(methylthio)butanoic acid | H-DL-Met-OH | (±)-2-Amino-4-(methylmercapto)butyric acid
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
M104886-25g
2
$9.90
100g
M104886-100g
2
$11.90
500g
M104886-500g
1
$35.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 179 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

DL-Methionine is an essential nonpolar α-amino acid with oxidative stress defense properties.
An essential nonpolar amino acid with oxidative stress defense properties

Specifications

Synonyms
DL-2-Amino-4-(methylthio)butanoic acid | H-DL-Met-OH | (±)-2-Amino-4-(methylmercapto)butyric acid
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
Methionine can prevent diseases related to hair, skin and nails. It increases the production of lecithin in liver, thus reducing cholesterol level. It is naturally used as a heavy metal chelating agent to regulate ammonia concentration in urine. This can
Storage
Store at 2-8°C, Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid504750429
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504750429
Canonical SmilesCSCCC(C(=O)O)N
IUPAC Name2-amino-4-methylsulfanylbutanoic acid
InChIKeyFFEARJCKVFRZRR-UHFFFAOYSA-N
INCHI1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
Isomeric SMILES CSCCC(C(=O)O)N
WGK Germany 1
RTECS PD0456000
Molecular Weight 149.21
Beilstein 636185
Reaxy-Rn 636185
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636185&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentMethionine and derivatives
Alternative Parents Alpha amino acids  Thia fatty acids  Amino acids  Sulfenyl compounds  Monocarboxylic acids and derivatives  Dialkylthioethers  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Methionine or derivatives - Alpha-amino acid - Thia fatty acid - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Thioether - Sulfenyl compound - Dialkylthioether - Amine - Organic oxygen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as methionine and derivatives. These are compounds containing methionine or a derivative thereof resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors sulfur-containing amino acid - alpha-amino acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
F2612444Certificate of AnalysisMay 26, 2026 M104886
F2612434Certificate of AnalysisMay 26, 2026 M104886
L2515597Certificate of AnalysisNov 13, 2025 M104886
L2515595Certificate of AnalysisNov 13, 2025 M104886
L2515588Certificate of AnalysisNov 13, 2025 M104886
C2513425Certificate of AnalysisFeb 15, 2025 M104886
G2523032Certificate of AnalysisFeb 15, 2025 M104886
G2512050Certificate of AnalysisFeb 15, 2025 M104886
C2513424Certificate of AnalysisFeb 15, 2025 M104886
C2513426Certificate of AnalysisFeb 15, 2025 M104886
C2513524Certificate of AnalysisFeb 15, 2025 M104886
J2425568Certificate of AnalysisOct 14, 2024 M104886
J2425569Certificate of AnalysisOct 14, 2024 M104886
J2425543Certificate of AnalysisOct 14, 2024 M104886
L2403416Certificate of AnalysisJun 27, 2024 M104886
F2429281Certificate of AnalysisJun 06, 2024 M104886
L2403276Certificate of AnalysisJun 06, 2024 M104886
F2429273Certificate of AnalysisJun 06, 2024 M104886
F2429285Certificate of AnalysisJun 06, 2024 M104886
L2209309Certificate of AnalysisNov 19, 2022 M104886
L2209502Certificate of AnalysisNov 19, 2022 M104886
H2209552Certificate of AnalysisJun 16, 2022 M104886
H2209553Certificate of AnalysisJun 16, 2022 M104886
H2209554Certificate of AnalysisJun 16, 2022 M104886
E2407012Certificate of AnalysisJun 16, 2022 M104886
E2407013Certificate of AnalysisJun 16, 2022 M104886
K2204792Certificate of AnalysisJun 16, 2022 M104886
L2318032Certificate of AnalysisJun 16, 2022 M104886
E2417036Certificate of AnalysisJun 16, 2022 M104886

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Chemical and Physical Properties
SolubilitySoluble in 5M HCl (100 mg/ml), water (56.6 mg/ml at 25 °C), acetic acid, and warm dilute alcoho. Insoluble in absolute alcohol.
SensitivityLight sensitive.
Melt Point(°C)281°C
Molecular Weight149.210 g/mol
XLogP3-1.900
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass149.051 Da
Monoisotopic Mass149.051 Da
Topological Polar Surface Area88.600 Ų
Heavy Atom Count9
Formal Charge0
Complexity97.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
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52. Linlin Zhang, Jie Wang, Chenglong Zhao, Feijin Zhou, Cheng Yao, Chan Song.  (2022)  Ultra-fast colorimetric detection of glutathione by magnetic Fe NPs with peroxidase-like activity.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2022.131750]
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90. Chan Song, Weiwen Zhao, Haibo Liu, Wei Ding, Linlin Zhang, Jie Wang, Yuewei Yao, Cheng Yao.  (2020)  Two-dimensional FeP@C nanosheets as a robust oxidase mimic for fluorescence detection of cysteine and Cu2+.  Journal of Materials Chemistry B,  (33): (7494-7500).  [PMID:32667961] [10.1039/D0TB00215A]
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102. Yong-hong Liu, Ting-ting Du, Jing-yuan Wan, Hua Zhao, Dan Huang, Jian-sha Li, Xin-hui Jiang.  (2019)  Simultaneous determination of thirteen substances related to NAFLD in mouse brain tissue using 3-aminobutyric acid as internal standard by HPLC–FLD.  BIOMEDICAL CHROMATOGRAPHY,  34  (3): (e4767).  [PMID:31785600] [10.1002/bmc.4767]
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106. Piaopiao Chen, Iqra Ilyas, Su He, Yichen Xing, Zhigang Jin, Chaobiao Huang.  (2019)  Ratiometric pH Sensing and Imaging in Living Cells with Dual-Emission Semiconductor Polymer Dots.  MOLECULES,  24  (16): (2923).  [PMID:31409040] [10.3390/molecules24162923]
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108. Wei Wang, Ruiguang Bai, Huimin Zhang, Xiaoyu Cai.  (2019)  Study of the effect of culture mediums on the amino acid metabolites for Corynebacterium glutamicum using high-speed micellar electrokinetic chromatography.  ELECTROPHORESIS,  40  (20): (2665-2671).  [PMID:31141615] [10.1002/elps.201900010]
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119. Yiting Pan, Qinzhen Li, Qin Zhou, Wan Zhang, Ping Yue, Changzhi Xu, Ximing Qin, Haizhu Yu, Manzhou Zhu.  (2018)  Cancer cell specific fluorescent methionine protected gold nanoclusters for in-vitro cell imaging studies.  TALANTA,      [PMID:30029373] [10.1016/j.talanta.2018.05.079]
120. Zhang Yue, Kang An, Deng Haishan, Shi Le, Su Shulan, Yu Li, Xie Tong, Shan Jinjun, Wen Hongmei, Chi Yumei, Han Shuying, Su Ruilin, Song Yilin, Chen Xi, Shaikh Armaan Basheer.  (2018)  Simultaneous determination of sulfur compounds from the sulfur pathway in rat plasma by liquid chromatography tandem mass spectrometry: application to the study of the effect of Shao Fu Zhu Yu decoction.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  410  (16): (3743-3755).  [PMID:29632971] [10.1007/s00216-018-1038-2]
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123. Juanzu Liu, Danyang Ji, Hongmin Meng, Lin Zhang, Junyan Wang, Zhongming Huang, Juan Chen, Jianjun Li, Zhaohui Li.  (2018)  A portable fluorescence biosensor for rapid and sensitive glutathione detection by using quantum dots-based lateral flow test strip.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2018.02.040]
124. Qing Xiong, Jing Jin, Liqiong Lv, Zhisi Bu, Shengqiang Tong.  (2018)  Chiral ligand exchange countercurrent chromatography: Enantioseparation of amino acids.  JOURNAL OF SEPARATION SCIENCE,  41  (6): (1479-1488).  [PMID:29323783] [10.1002/jssc.201701117]
125. Qianzhu Zhao, Shengwen Yao, Shi-Yi Ou.  (2017)  Maillard volatiles in baked products as affected by feruloylated oligosaccharides from maize bran.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,      [PMID:] [10.1080/10942912.2017.1285788]
126. Fei Qu, Yanqun Liu, Haili Lao, Yaping Wang, Jinmao You.  (2017)  Colorimetric detection of heparin with high sensitivity based on the aggregation of gold nanoparticles induced by polymer nanoparticles.  NEW JOURNAL OF CHEMISTRY,  41  (19): (10592-10597).  [PMID:] [10.1039/C7NJ02381B]
127. Huaping Peng, Meili Jian, Haohua Deng, Wenjun Wang, Zhongnan Huang, Kaiyuan Huang, Ailin Liu, Wei Chen.  (2017)  Valence States Effect on Electrogenerated Chemiluminescence of Gold Nanocluster.  ACS Applied Materials & Interfaces,      [PMID:28398723] [10.1021/acsami.7b02446]
128. Pin Wu, Hua-Ming Xiao, Jun Ding, Qian-Yun Deng, Fang Zheng, Yu-Qi Feng.  (2017)  Development of C60-based labeling reagents for the determination of low-molecular-weight compounds by matrix assisted laser desorption ionization mass (I): Determination of amino acids in microliter biofluids.  ANALYTICA CHIMICA ACTA,      [PMID:28193366] [10.1016/j.aca.2017.01.018]
129. Peng Huaping, Deng Haohua, Jian Meili, Liu Ailin, Bai Fengqiao, Lin Xinhua, Chen Wei.  (2016)  Electrochemiluminescence sensor based on methionine-modified gold nanoclusters for highly sensitive determination of dopamine released by cells.  MICROCHIMICA ACTA,  184  (3): (735-743).  [PMID:] [10.1007/s00604-016-2058-2]
130. Xiaohong Zhang, Zhidong Zhao, Xiongwei Lou, Jian Li, Guohua Hui.  (2016)  A maltose, L-rhamnose sensor based on porous Cu foam and electrochemical amperometric i-t scanning method.  Journal of Food Measurement and Characterization,  11  (2): (548-555).  [PMID:] [10.1007/s11694-016-9422-0]
131. Qianqian Du, Fei Qu, Beibei Mao, Shuyun Zhu, Jinmao You.  (2016)  Turn-on fluorescent detection of melamine based on Ag nanoclusters–Hg2+ system.  NEW JOURNAL OF CHEMISTRY,  40  (10): (8459-8464).  [PMID:] [10.1039/C6NJ01338D]
132. Wei Wang, Lihong Ma, Ping Lin, Kaixuan Xu.  (2016)  Separation and detection of amino acid metabolites of Escherichia coli in microbial fuel cell with CE.  ELECTROPHORESIS,  37  (14): (2106-2111).  [PMID:27121957] [10.1002/elps.201600007]
133. Qiwei Yang, Zhiping Wang, Zongbi Bao, Zhiguo Zhang, Yiwen Yang, Qilong Ren, Huabin Xing, Sheng Dai.  (2016)  New Insights into CO2 Absorption Mechanisms with Amino-Acid Ionic Liquids.  ChemSusChem,  (8): (806-812).  [PMID:27061812] [10.1002/cssc.201501691]
134. Datong Wu, Pengfei Cai, Zhihao Tao, Yuanjiang Pan.  (2015)  Specific ionic effect for simple and rapid colorimetric sensing assays of amino acids using gold nanoparticles modified with task-specific ionic liquid.  ANALYTICA CHIMICA ACTA,      [PMID:26703268] [10.1016/j.aca.2015.10.033]
135. Xiao-dong Tang, Yong-fen Zhang, Jing-jing Li.  (2015)  Alkylation of thiophenic compounds catalyzed by deep eutectic solvents.  CATALYSIS COMMUNICATIONS,      [PMID:] [10.1016/j.catcom.2015.07.014]
136. Wenjuan Guo, Na Sun, Xiaoli Qin, Meishan Pei, Luyan Wang.  (2015)  A novel electrochemical aptasensor for ultrasensitive detection of kanamycin based on MWCNTs–HMIMPF6 and nanoporous PtTi alloy.  BIOSENSORS & BIOELECTRONICS,      [PMID:26208174] [10.1016/j.bios.2015.06.081]
137. Zhe Zhang, Ningchen Tian, Lingzhi Zhang, Ling Wu.  (2015)  Inhibition of the corrosion of carbon steel in HCl solution by methionine and its derivatives.  CORROSION SCIENCE,      [PMID:] [10.1016/j.corsci.2015.05.048]
138. Junhe Lu, Juan Shao, Deyang Kong.  (2014)  Nucleophilic substitution as a mechanism of atrazine sequestration in soil.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:25463223] [10.1016/j.jhazmat.2014.11.001]
139. Hao-Hua Deng, Ling-Na Zhang, Shao-Bin He, Ai-Lin Liu, Guang-Wen Li, Xin-Hua Lin, Xing-Hua Xia, Wei Chen.  (2014)  Methionine-directed fabrication of gold nanoclusters with yellow fluorescent emission for Cu2+ sensing.  BIOSENSORS & BIOELECTRONICS,      [PMID:25461187] [10.1016/j.bios.2014.10.071]
140. Qiao Tong, Weijie Shen, Lu Zhang, Yu Cao, Xi Zou, Tingting Shi, Rang Xiao Zhuang, Shourong Liu, Jianjun Xi.  (2025)  A “turn-on” fluorescence polyethyleneimine-based nanosensor chemosensor for sensing of l-lysine.  TALANTA,      [PMID:40184936] [10.1016/j.talanta.2025.128045]
141. Yuying Han, Xingyu Hou, Yali Li, Xiaopeng Yang, Xue Sun, Xinxin Bian, Na Sun, Yuguang Lv, Lixin Ding, Ze Li.  (2025)  A ratiometric fluorescent probe for a smartphone-based dual-emission carbon dot fluorescence sensor for the rapid detection of 5-HIAA.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113448]
142. Ying Yang, Liuyan Wei, Weiqin You, Huisha Huang, Shuai Wang, Dandan Hou, Chujun Qin, Zhiheng Su, Mei Li.  (2025)  A simple colorimetric and paper-based-smartphone sensing platform based on the enhanced peroxidase-like activity of Al doping Prussian blue for point-of-care detection of GSH.  TALANTA,      [PMID:40164025] [10.1016/j.talanta.2025.128020]
143. Ye Shang, Suyi Liu, Chunxiao Liang, Tenukeguli Tuliebieke, Shujing Chen, Kunze Du, Xiaoxuan Tian, Jin Li, Jun He, Hua Jin, Yanxu Chang.  (2025)  A strategy integrated DNA barcoding with metabolomics for screening distinguishable combinatorial chemical quality marker between Pheretima aspergillum and Pheretima vulgaris Chen.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:39893778] [10.1016/j.jpba.2025.116716]
144. Zihan Wang, Yihong Chen, Zexian Chen, Jiarong Duan, Huiping Wang, Erhua Guo, Jianhui Zhi, Shaomin Shuang, Chuan Dong, Jun Li, Xiaojuan Gong.  (2025)  A trinity sensing platform for uric acid detection in clinical samples using Fe-functionalized carbon quantum dot nanozymes.  TALANTA,      [PMID:40164024] [10.1016/j.talanta.2025.128007]
145. Yusha Huang, Longcheng Gong, Chengli Xie, Wenling Qin, Min Wang, Lianzhe Hu, Zhining Xia.  (2025)  Anchoring biomimetic Zn site in metal–organic framework nanozyme to enhance phosphatase-like catalytic activity for discrimination of organophosphorus pesticides.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160046]
146. Zhiyu Zhang, Cheng Yang, Di Zhao, Yuanqing Zhao, Lixin Li, Zhonghua Li, Zhenqiang Zhang, Kai Hu.  (2024)  Boric Acid Functionalized Hypercrosslinked Polymers for Selective Extraction of Trace Catecholamines and Their Metabolites in Rat Serum.  JOURNAL OF SEPARATION SCIENCE,  47  (18): (e202400418).  [PMID:39304642] [10.1002/jssc.202400418]
147. Minghui Jiang, Xiao Liu, Yurui Xu, Shiyu Li, Xiangju Liu, Xiaokai Niu, Lei Lu, Xinru Sun, Zhitian Xie, Ziming Wang, Su-ping Cui.  (2025)  Corrosion Inhibition Effect and Mechanism of Eco-Friendly Corrosion Inhibitors on Mild Steel in Simulated Concrete Pore Solution: Experimental and Theoretical Studies.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.4c08318]
148. Yingfei Hui, Hao Guo, Mingyue Wang, Liping Peng, Borong Ren, Yanyan Ma, Wu Yang.  (2025)  Deep machine learning-assisted MOF@COF fluorescence/colorimetric dual-mode intelligent ratiometric sensing platform for sensitive glutathione detection.  TALANTA,      [PMID:40121993] [10.1016/j.talanta.2025.127990]
149. Houwen Hu, Haoming Xing, Linfan Wang, Sineng Gao, Yihao Zhang, Liwei Gao, Guoqiang Guo, Chenjie Gu, Da Chen.  (2024)  Lateral flow assay with dual-emission nitrogen-doped carbon dots for ratiometric fluorescent determination of nitrite in food.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.111247]
150. Wenli Zhu, Miao Hu, Guanghua Su, Weifang Jiang, Hancong Du, Kaxi Chen, Jinfang Nie, Lang Zhang, Xuehui Tang, Yun Zhang.  (2025)  Nanoprobe-free nanosensor with Tyndall-effect readout for colorimetric detection of alkaline phosphatase.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113295]
151. Zhao Xiaoben, He Tao, Wang Shuainan, He Song.  (2025)  N-doped activated carbon for enhanced CO2 sorption through self-activation.  Biomass Conversion and Biorefinery,      [PMID:] [10.1007/s13399-025-06732-0]
152. Juanmin Li, Shunsheng Zhao, Lihua Bai, Xiangrong Liu, Li Shang.  (2025)  Ratiometric fluorescence aptasensor for lysozyme based on the controllable excimer formation of perylene probe.  TALANTA,      [PMID:39756257] [10.1016/j.talanta.2025.127521]
153. Yang Chunlei, Xu Guiju, Hou Chenghao, Zhang Hongwei.  (2025)  Ratiometric fluorescence nanoprobe based on nitrogen-doped carbon dots for Cu2+ and Fe3+ detection.  Scientific Reports,  15  (1): (1-9).  [PMID:39979366] [10.1038/s41598-025-89327-z]
154. Zhou Mengyan, Zhang Zhihui, Zheng Qi, Yu Mingdi, Si Mengxu, Wu Sirui, Zhang Yanan, Ding Shushu, Fu Ding-Yi.  (2025)  Ratiometric fluorescence quantification of folic acid utilizing D-penicillamine-based carbon dots in conjunction with glutathione S-transferase-Au nanoclusters.  MICROCHIMICA ACTA,  192  (4): (1-13).  [PMID:40080078] [10.1007/s00604-025-07062-8]
155. Chen Kun, Ma Chaoqun, Chen Guoqing, Yang Taiqun, Gao Hui, Li Lei, Hu Anqi, Cao Jun, Zheng Chenkai, Ma Longyao, Chen Zehao.  (2025)  SERS Substrate Based on COFs@Ag for Rapid Detection of Pefloxacin.  Plasmonics,      [PMID:] [10.1007/s11468-025-02935-3]
156. Yiqun Hu, Qingqing Chen, Aifang Zhang, Liyuan Zhang, Hansong Dong.  (2024)  Strain of Xanthomonas oryzae pv. oryzae Loses Virulence through Dysregulation of Cardiolipin Synthase.  Plants-Basel,  13  (18): (2576).  [PMID:39339552] [10.3390/plants13182576]
157. Xinwei Zhang, Ziping Wang, Yu Bai, Yulun Hu, Qing Chen, Yueping Liu, Mingming Chang.  (2025)  Therapeutic Effect of a Near-Infrared Responsive MTX-Mn3O4@PDA Nano-Delivery System on Rheumatoid Arthritis.  Advanced Therapeutics,      [PMID:] [10.1002/adtp.202400345]
158. Shen Zhang, Zhuo Wang, Tianyu Miao.  (2025)  Tryptophan-functionalized gold nanoclusters used as a fluorescence sensor for alizarin determination.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:40054145] [10.1016/j.saa.2025.125963]
159. Xueting Liu, Yajing Zhu, Yutong Jing, Yuheng Zhu, Lichuan Wu, Wenqian Nong.  (2025)  γ-polyglutamic acid-encapsulated metformin-loaded Ga-Car-MOF and hydrocaffeic acid-modified chitosan double-layer microneedle patch for accelerated bacterial-infected wound healing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39952522] [10.1016/j.ijbiomac.2025.140959]
160. Ruoqi Wang, Qiao Zhang, Lei Yu, Yue Sun, Yunwei Gao, Dazhong Shen.  (2025)  In-situ formation coreactant promoters via pre-oxidation to enhance electrochemiluminescence of Eu-doped methionine-stabilized Au nanoclusters and application in label-free molecularly imprinted sensor of neuron specific enolase.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2025.138243]
161. Jingtao Huang, Ying Ying Nie, Yu Meng Yang, Xin Ying Long, Yongpeng He, Lei Zhan, Cheng Zhi Huang.  (2025)  Chiral Carbon Dots as Optical Probes: Selective Detection of Acetylcholinesterase via Enhanced Photoluminescence.  ANALYTICAL CHEMISTRY,      [PMID:40711814] [10.1021/acs.analchem.5c00073]
162. Xiaoxuan Ren, Yue Sun, Shengjie Li, Junyuan Bai, Xuwen Gao, Guizheng Zou.  (2025)  Direct and Glow Chemiluminescence of Dual-Stabilizer-Capped Au Nanocrystals for Automatic Immunoassays.  ANALYTICAL CHEMISTRY,      [PMID:40590625] [10.1021/acs.analchem.5c02425]
163. Siqi Chen, Wei Tang, Huayan Luo, Qingqing Peng, Li Wang, Ruifeng Xie, Zhongmin Su, Fang Chai.  (2025)  Fluorescent sensing of iron in food and antibacterial actions using rapid synthetic orange-emitting gold nanoclusters.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.118762]
164. Na-Na Ran, Quan Luo, Hong-Wei Li, Yuqing Wu.  (2025)  A novel fluorescence nanoprobe for unique determination of chlortetracycline based on zinc-doped carbon dots.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.137935]
165. Boyuan Li, Wenjie Zhao, Ningning Wang, Lingbo Qu, Lin Zhang, Zhaohui Li.  (2025)  A Portable Smartphone-assisted Fluorescent Probe for Visual Detection of Hydrogen Peroxide.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2025.113138]
166. Haifeng Luo, Yuchen Zheng, Shizhao Ren, Wangchuan Xiao, Rongrong Xue, Wei Han, Fenghua Chen.  (2025)  Co-Amorphous Andrographolide–Lysine with Unexpectedly Enhanced Solubility.  Crystals,  15  (9): (752).  [PMID:] [10.3390/cryst15090752]
167. Yu-Ning Ma, Fei-Fei Yu, Yan Ao, Yu-Feng Li, Yao Yuan, Shang-Wei Hou, Yi-Yi Cao, Jing Xi, Yang Luan, Xin-Yu Zhang.  (2025)  Bilirubin Degradation by Hypochlorous Acid: Identification of Products and Their Formation Ex Vivo and In Vivo.  ChemistrySelect,  10  (32): (e04077).  [PMID:] [10.1002/slct.202504077]
168. Chengfu Su, Xin Peng, Jingying Tan, Yujie Chang, Naifei Pan, Haiying Chen, Xiaokai Xu, Lei Han.  (2025)  Dual-Emission Carbon Dot Nanozymes Mitigate Salt Stress and Enhance Photosynthesis for Crop Germination and Growth.  Advanced Science,      [PMID:41017738] [10.1002/advs.202506906]
169. Yan Shen, Xiaochen Liu, Junling Li, Jingsi Chen, Jiafu Li.  (2025)  Revealing the impact of side-chains in amino acids on the formation of haloacetamides during chlorination.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40997468] [10.1016/j.jhazmat.2025.139945]
170. Ziyu Kuai, Yibing Huang, Fengjie Hao, Wantong Jiang, Mengmeng Niu, Yu qin, Ao Song, Yuran Deng, Youzhong Wan, Quan Luo.  (2025)  Atomic-Level Engineering of Protein-Templated Gold Clusterzymes with Tunable Fluorescence and Multi-Enzyme Activities for Antiaging Treatment.  ACS Applied Materials & Interfaces,      [PMID:40957724] [10.1021/acsami.5c11714]
171. Ying Xu, Cong Dai, Zhifeng Xu.  (2025)  Dual-channel ratiometric sensing of hypochlorous acid based on organic cage with red and green fluorescence.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:40945009] [10.1016/j.saa.2025.126928]
172. Dan Tang, Qin Wang, Shaojing Zhao, Jianing Yi, Minhuan Lan, Jie Zeng, Lei Huang.  (2023)  Environmental synthesis of yellow fluorescent carbon dots for on-off-on detection of mercury and cysteine.  INORGANIC CHEMISTRY COMMUNICATIONS,      [PMID:] [10.1016/j.inoche.2023.111160]
173. Wang Yijie, Li Qiulan, Xia Qinghai, Yang Yaling, Yang Dezhi.  (2023)  A portable and quantitative detection of xanthine and xanthine oxidase based on cascade enzymatic reactions of Fe3O4@MWCNTs/Hemin.  JOURNAL OF MATERIALS SCIENCE,  58  (17): (7441-7455).  [PMID:] [10.1007/s10853-023-08449-9]
174. Dan Zhao, Jingjing Huang, Juan Li, Xiao Ma, Fang Wang, Honglei Zhang, Jiaze Xie, Jian Sun, Chuanxia Chen.  (2023)  Ultrasensitive colorimetric and fluorescent dual-readout assay for D-penicillamine based on the chloride boosted oxidative ability of copper ions.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.108535]
175. Jie Wang, Chenglong Zhao, Feijin Zhou, Hui Lu, Zhenhong Huang, Cheng Yao, Chan Song.  (2022)  Dual mimic enzyme properties of Fe nanoparticles embedded in two-dimensional carbon nanosheets for colorimetric detection of biomolecules.  ANALYST,  148  (1): (146-152).  [PMID:36475531] [10.1039/D2AN01704K]
176. Lihong Shi, Xiaorui Dong, Guomei Zhang, Yan Zhang, Caihong Zhang, Chuan Dong, Shaomin Shuang.  (2021)  Lysosome targeting, Cr(VI) and L-AA sensing, and cell imaging based on N-doped blue-fluorescence carbon dots.  Analytical Methods,  13  (32): (3561-3568).  [PMID:34313265] [10.1039/D1AY00977J]
177. Jinjie Hou, Pei Jia, Kairong Yang, Tong Bu, Xinyu Sun, Li Wang.  (2021)  Facile preparation of Ru@V2O4 nanowires exhibiting excellent tetra-enzyme mimetic activities for sensitive colorimetric H2O2 and cysteine sensing.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.130266]
178. Zhen Wu, Jinlong Wang, Xing Cheng, Yue Tang, Lian Xia, Xiaojuan Niu, Yuangen Wu.  (2025)  A novel fluorescent sensor for highly sensitive detection of ascorbic acid in food based on inhibiting phosphatase-like activity of Zr-based MOF.  FOOD CHEMISTRY,      [PMID:39808980] [10.1016/j.foodchem.2025.142837]
179. Chuanxia Chen, Jadera Talap, Chenghui Zhang, Chang Yu, Chenhui Zhao, Yushu Li, Fan Yang, Yizhong Lu, Jian Sun.  (2025)  Ascorbic acid-amplified robust fluorescent assay for versatile detection of acid phosphatase activity.  ANALYTICA CHIMICA ACTA,      [PMID:40750200] [10.1016/j.aca.2025.344408]
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