DSPE PEG Maleimide, DSPE-PEG-MAL - Low Endotoxin,MW 2000 Da , CAS No.474922-22-0

CAS: 474922-22-0 Cat. No.: GMP1511065 PubChem CID: 156594503
AVAILABLE TO ORDER
GRADE & PURITY Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. MW 2000 Da
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25mg
GMP1511065-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$259.90
100mg
GMP1511065-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90
500mg
GMP1511065-500mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$2,199.90
1g
GMP1511065-1g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$3,599.90
Enter a quantity for the sizes you want to add.
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Why this grade

Low Endotoxin,MW 2000 Da Low Endotoxin for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjμgated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjμgate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drμg delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drμgs. These materials can also be used for targeted drμg delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

DSPE-PEG(2000) maleimide is suitable for conjugation with photon-sensitive cell penetrating peptides (psCPP) to prepare nanostructured lipid carrier. It is also suitable for non-covalently functionalizing oxidized multi-walled carbon nanotubes (O-MWCNs).

Specifications

Specifications & Purity
Low Endotoxin, MW 2000 Da
Biochemical and Physiological Mechanisms
DSPE-PEG(2000) maleimide is used to prepare conjugated polymer nanoparticles. It is suitable for its use in the synthesis of functional conjugates
Storage
Protected from light, Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Low Endotoxin
Names and Identifiers
Canonical SmilesCCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC.N
IUPAC Nameazane;[3-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxycarbonylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
InChIKeyHMLYGTOVHVFLDS-UHFFFAOYSA-N
INCHI1S/C53H96N3O14P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-51(60)67-45-47(70-52(61)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-69-71(63,64)68-42-39-55-53(62)66-44-43-65-41-38-54-48(57)37-40-56-49(58)35-36-50(56)59;/h35-36,47H,3-34,37-46H2,1-2H3,(H,54,57)(H,55,62)(H,63,64);1H3
PubChem CID 156594503

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolubility: Soluble in chloroform and warm water;
SensitivityLight & Moisture sensitive
Citations of This Product
References
1. Liu Yanhong, Gong Liming, Feng Jing, Xiao Congcong, Liu Chenfei, Chen Bohan, Chen Liqing, Jin Mingji, Guan Youyan, Gao Zhonggao, Huang Wei.  (2025)  Co-delivery of axitinib and PD-L1 siRNA for the synergism of vascular normalization and immune checkpoint inhibition to boost anticancer immunity.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-22).  [PMID:40059141] [10.1186/s12951-025-03170-y]
2. Xiaozhuo Ba, Tao Ye, Yu He, Yonghua Tong, Haojie Shang, Jian Wu, Wen Deng, Zichen Zhong, Xiaoqi Yang, Kangyang Wang, Yabin Xie, Kehua Jiang, Xiaolin Guo, Kun Tang.  (2025)  Engineered macrophage membrane-coated nanoparticles attenuate calcium oxalate nephrocalcinosis-induced kidney injury by reducing oxidative stress and pyroptosis.  Acta Biomaterialia,      [PMID:39947306] [10.1016/j.actbio.2025.02.021]
3. Jinghao Fan, Fang Wang, Shiyi Chen, Mingkang Liu, Wenping Pan, Wantao Wang, Wenzheng Ma, Yiwen Xian, Yongmiao Chen, Xue Wei, Chenqi Wang, Chunhong Cui, Hongmei Liu, Decheng Wu.  (2025)  Boosting Immune Checkpoint Therapy Efficacy of Pancreatic Cancer by Cell-Anchoring Probiotic.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202502197]
4. Yuwen Song, Tingting Xu, Hao Li, Jing Liu, Shumin Cao, Yichen Yang, Nianlu Li, Peiwen Lv, Min Han, Haohan Sun, Guangfu Dang, Jianxin Li, Hao Sun, Tao Xin, Huitang Xia, CanWei Zhang.  (2025)  Delivery of Itgb1-siRNA by triptolide-modified and anti-Flt1 peptide-guided ionizable cationic LNPs for targeted therapy of corneal neovascularization.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40324532] [10.1016/j.jconrel.2025.113811]
5. Yuxiang Gao, Rong Ma, Lijun Zhu, Zhong Du, Jiabao Xiong, Chi Zhang, Xueliang Zhang, Cailing Ma, Nuernisha Alifu.  (2025)  Theranostic Nanoprobes Assisted NIR-II Fluorescence Imaging for Efficient Angiography and Tumor Therapy.  ACS Omega,      [PMID:40454026] [10.1021/acsomega.5c01553]
6. Chao Fang, Daihan Xie, Fanlei Kong, Xin Yu, Jingting Yin, Yu Huo, Chunxia Su.  (2026)  Lipid-Engineered Small-Sized Metal-Organic Frameworks for Targeted Delivery of Anlotinib in Lung Cancer Treatment.  International Journal of Nanomedicine,      [PMID:] [10.2147/IJN.S566873]
Solution Calculators
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