FABP-IN-1 - ≥98% , CAS No.2132990-90-8

CAS: 2132990-90-8 Cat. No.: F651827 Molecular Weight: 482.52

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

FABP-IN-1 (Compounds 4b) is a high affinity fatty acid binding protein (FABP) inhibitor. FABP-IN-1 inhibits FABP3 , FABP5 , and FABP7 with K i values of 0.69 μM, 0.55 μM and 0.67 μM, respectively. FABP-IN-1 displays potent antinociceptive effects

In Vivo

FABP-IN-1 (Compounds 4b; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice injected with complete Freund’s adjuvant (CFA) Dosage: 20 mg/kg Administration: Intraperitoneal injection; for 90 minutes Result: Displayed potent antinociceptive effects in CFA model.

Form:Solid

IC50& Target:Ki: 0.69 μM (FABP3), 0.55 μM (FABP5) and 0.67 μM (FABP7)

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

FABP-IN-1 (Compounds 4b) is a high affinity fatty acid binding protein (FABP) inhibitor. FABP-IN-1 inhibits FABP3 , FABP5 , and FABP7 with K i values of 0.69 μM, 0.55 μM and 0.67 μM, respectively. FABP-IN-1 displays potent antinociceptive effects.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O=C([C@H]1[C@@H](C(C=CC=C2)=C2OC)[C@H](C(O)=O)[C@@H]1C(C=CC=C3)=C3OC)OC4=CC=CC5=C4C=CC=C5
• Molecular Weight: 482.52

Chemical and Physical Properties

• Solubility: DMSO : 200 mg/mL (414.49 mM; Need ultrasonic)