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· · COA & SDS available for every product · Same-day shipping on in-stock items (+)-Fluprostenol - ≥95%(HPLC) , Agonist of FP receptor, CAS No.54276-17-4, Agonist of FP receptor
Synonyms
(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid | rac-(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-
Shipped In
Ice chest + Ice pads
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Why this grade ≥95%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
(5Z)-7-[(1R, 2R, 3R, 5S)-3, 5-Dihydroxy-2-[(1E, 3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid | rac-(5Z)-7-[(1R, 2R, 3R, 5S)-3, 5-dihydroxy-2-{(1E, 3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-
Specifications & Purity
≥95%(HPLC)
Biochemical and Physiological Mechanisms
Prostaglandin F2α(FP) receptor agonist (Ki= 49.9 nM; EC50= 2.4 nM). Stimulates intracellular calcium mobilization in cloned human ocular FP receptors, rat A7r5 cells and mouse 3T3 cells (EC50values are 17.5, 19.1 and 37.3 nM respectively). Analog of prost
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Agonist of FP receptor
Names and Identifiers Canonical Smiles C1C(C(C(C1O)C=CC(COC2=CC=CC(=C2)C(F)(F)F)O)CC=CCCCC(=O)O)O IUPAC Name (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid InChIKey WWSWYXNVCBLWNZ-QIZQQNKQSA-N INCHI 1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1 Isomeric SMILES C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](COC2=CC=CC(=C2)C(F)(F)F)O)C/C=C\CCCC(=O)O)O Alternate CAS 40666-16-8,54276-17-4,55028-71-2 (mono-hydrochloride salt) MeSH Entry Terms fluprostenol;fluprostenol monosodium salt;fluprostenol, ((1alpha(Z),2beta(1E,3R*),3alpha,5alpha)-(+-))-isomer;fluprostenol, ((1R-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-(+-))-isomer;ICI 81,008 Molecular Weight 458.47 Reaxy-Rn 35827403 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35827403&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Lipids and lipid-like molecules Class Fatty Acyls Subclass Eicosanoids Intermediate Tree Nodes Not available Direct Parent Prostaglandins and related compounds Alternative Parents Long-chain fatty acids Trifluoromethylbenzenes Phenoxy compounds Phenol ethers Alkyl aryl ethers Halogenated fatty acids Hydroxy fatty acids Unsaturated fatty acids Cyclopentanols Cyclic alcohols and derivatives Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Organofluorides Carbonyl compounds Alkyl fluorides Hydrocarbon derivatives Molecular Framework Aromatic homomonocyclic compounds Substituents Prostaglandin skeleton - Long-chain fatty acid - Trifluoromethylbenzene - Phenoxy compound - Phenol ether - Alkyl aryl ether - Halogenated fatty acid - Hydroxy fatty acid - Monocyclic benzene moiety - Fatty acid - Benzenoid - Unsaturated fatty acid - Cyclopentanol - Cyclic alcohol - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Ether - Monocarboxylic acid or derivatives - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Alcohol - Carbonyl group - Organic oxide - Alkyl fluoride - Organofluoride - Organohalogen compound - Alkyl halide - Aromatic homomonocyclic compound Description This compound belongs to the class of organic compounds known as prostaglandins and related compounds. These are unsaturated carboxylic acids consisting of a 20 carbon skeleton that also contains a five member ring, and are based upon the fatty acid arachidonic acid. External Descriptors prostaglandins Falpha - hydroxy monocarboxylic acid - (trifluoromethyl)benzenes Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10(mg/mL)) Molecular Weight 458.500 g/mol XLogP3 2.900 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 11 Exact Mass 458.192 Da Monoisotopic Mass 458.192 Da Topological Polar Surface Area 107.000 Ų Heavy Atom Count 32 Formal Charge 0 Complexity 636.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 5 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 2 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 2 Covalently-Bonded Unit Count 1
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