≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Fmoc-Lys-OH is a lysine derivative commonly used in the synthesis of active compounds.
| Pubchem Sid | 504764529 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504764529 |
| Canonical Smiles | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCCN)C(=O)O |
| IUPAC Name | (2S)-6-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid |
| InChIKey | YRKFMPDOFHQWPI-IBGZPJMESA-N |
| INCHI | 1S/C21H24N2O4/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25)/t19-/m0/s1 |
| Isomeric SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CCCCN)C(=O)O |
| Molecular Weight | 368.4 |
| Reaxy-Rn | 5912402 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5912402&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Fluorenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorenes |
| Alternative Parents | Alpha amino acids and derivatives Medium-chain fatty acids Amino fatty acids Quaternary ammonium salts Carbamate esters Carboxylic acid salts Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organic zwitterions Organic salts Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Fluorene - Alpha-amino acid or derivatives - Medium-chain fatty acid - Amino fatty acid - Fatty acyl - Fatty acid - Carbamic acid ester - Quaternary ammonium salt - Amino acid or derivatives - Amino acid - Carboxylic acid salt - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Primary aliphatic amine - Primary amine - Organic zwitterion - Organic salt - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Amine - Aromatic homopolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2517463 | Certificate of Analysis | Nov 19, 2025 | F105970 |
| K2517464 | Certificate of Analysis | Nov 19, 2025 | F105970 |
| K2517466 | Certificate of Analysis | Nov 19, 2025 | F105970 |
| K2520849 | Certificate of Analysis | Nov 19, 2025 | F105970 |
| J2529605 | Certificate of Analysis | Nov 07, 2025 | F105970 |
| F2424225 | Certificate of Analysis | Jun 25, 2024 | F105970 |
| F2424226 | Certificate of Analysis | Jun 25, 2024 | F105970 |
| L2318400 | Certificate of Analysis | Dec 25, 2023 | F105970 |
| E2415083 | Certificate of Analysis | Dec 22, 2023 | F105970 |
| L2318401 | Certificate of Analysis | Dec 22, 2023 | F105970 |
| L2318402 | Certificate of Analysis | Dec 22, 2023 | F105970 |
| L2202047 | Certificate of Analysis | Dec 06, 2022 | F105970 |
| L2202064 | Certificate of Analysis | Dec 06, 2022 | F105970 |
| L2202499 | Certificate of Analysis | Dec 06, 2022 | F105970 |
| Sensitivity | Moisture sensitive |
|---|---|
| Specific Rotation[α] | +14.8°(C=1 3N HCl) |
| Molecular Weight | 368.400 g/mol |
| XLogP3 | 0.500 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 9 |
| Exact Mass | 368.174 Da |
| Monoisotopic Mass | 368.174 Da |
| Topological Polar Surface Area | 102.000 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 490.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Lin Yi, Li Mengyao, Luo Zijin, Meng Yanan, Zong Yan, Ren Hongyu, Yu Xiaolu, Tan Xiaoqiong, Liu Fan, Wei Tuo, Cheng Qiang. (2025) Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles. NATURE MATERIALS, [PMID:40890498] [10.1038/s41563-025-02320-9] |
| 2. Qiu Wang, Yi Lin, Zijin Luo, Jiahui Xiao, Keqing Xu, Xiaolu Yu, Yanan Meng, Mengyao Li, Hongyu Ren, Fan Liu, Xiaoqiong Tan, Han Wen, Tuo Wei, Qiang Cheng. (2025) Hydrogen Bond-Assisted Two-Component Lipid Nanoparticles for Spleen-Specific mRNA Delivery. Journal of the American Chemical Society, [PMID:41208607] [10.1021/jacs.5c14194] |
| 3. Qiu Wang, Yi Lin, Jiahui Xiao, Keqing Xu, Zijin Luo, Hongyu Ren, Fan Liu, Lu Jia, Tuo Wei, Qiang Cheng. (2026) Optimizing Peptide Ionizable Lipids Enables Efficient and Low-Toxicity mRNA Delivery for In Vivo Prime Editing and Protein Replacement Therapy. ADVANCED MATERIALS, [PMID:41656866] [10.1002/adma.202522552] |
