Gallopamil hydrochloride - 10mM in DMSO , CAS No.16662-46-7

CAS: 16662-46-7 Cat. No.: G655189 Molecular Weight: 521.1

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC 50 of 10.9 μM . Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent .

In Vivo

Gallopamil hydrochloride (Methoxyverapamil hydrochloride; i.v.; 0.2 mg/kg; for 5 min) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF). Gallopamil significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats weighing 290-370 gDosage: 0.2 mg/kg Administration: i.v.; 5 min Result: Markedly reduced VT and totally prevented VF.

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC 50 of 10.9 μM

Storage

Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl
• Alternate CAS: 16662-47-8
• Molecular Weight: 521.1