GI-530159 - Moligand™, 10 mM in DMSO , CAS No.69563-88-8

CAS: 69563-88-8 Cat. No.: G1500485 Molecular Weight: 518.45 EC Number: 626-703-8
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
G1500485-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$28.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC 50 of 0.76 μM for TREK1 . GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ACTIVATOR
Names and Identifiers
Isomeric SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)OC3=CC=C(C=C3)N)(C(F)(F)F)C(F)(F)F)OC4=CC=C(C=C4)N
WGK Germany 3
RTECS CY1213000
Molecular Weight 518.45
Reaxy-Rn 8879443
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8879443&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)159-163°C
Documents & Articles
Citations of This Product
References
1. Lidong Cao, Yaqing Wen, Xingzhong Fang, Guofei Chen.  (2023)  Synthesis of highly thermoplastic polyamide-imides with high transparency and low coefficient of thermal expansion.  POLYMER,      [PMID:] [10.1016/j.polymer.2023.126093]
2. Chaoying Liao, Zhaozhu Zhang, Yaohui He, Junya Yuan, Mingming Yang, Peilong Li, Wei Jiang, Yongmin Liang, Weimin Liu.  (2025)  Bioinspired Antiwear Poly(urea-imide) Composites: Influence of Tribology on Polymer Crystal Structure.  Small,      [PMID:39780741] [10.1002/smll.202408249]
3. Chaoying Liao, Zhaozhu Zhang, Yaohui He, Mingming Yang, Junya Yuan, Peilong Li, Yongmin Liang.  (2025)  Liquid metal microcapsules induced formation of dual-layer tribofilm for enhanced wear resistance in fabric composites.  TRIBOLOGY INTERNATIONAL,      [PMID:] [10.1016/j.triboint.2025.110598]
Solution Calculators
Reviews

Customer Reviews

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