[Glu1] Fibrinopeptide B(TFA salts), CAS No.103213-49-6(free)

CAS: 103213-49-6(free) Cat. No.: G777273 Molecular Weight: 1570.57(free base)

GRADE & PURITY ≥98%

Overview

Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer. It is cleaved off from the N-terminal of the fibrinogen β chain.This peptide is composed of 14 amino acids.

Application

[Glu1]-Fibrinopeptide B human has been used:
during LC-MS to avoid cross-contamination and to analyze the performance of mass spectrometer and LC-instrument
for two-point calibration during 2D (dimensional) gel electrophoresis and protein identification by mass spectrometry of histidine (his)-Pup (prokaryotic ubiquitin-like protein) isolated from Mycobacterium smegmatis
for two-point calibration during one-dimensional gel electrophoresis and tandem mass spectrometry (MS) for the characterization of soluble protein sample obtained from the salivary gland homogenates of Cimex lectularius
as a standard for the correction of mass drift in data obtained from MS and MS/MS performed on peptides obtained from trypsin-digestion of protein disulfide isomerase (PDI)

Specifications

Product Name

[Glu1] Fibrinopeptide B(TFA salts), CAS No.103213-49-6(free)

Synonyms

Fibrinopeptide B | 1-L-Glutamic Acid-Fibrinopeptide B | H-GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG-OH | GLU-GLY-VAL-ASN-ASP-ASN-GLU-GLU-GLY-PHE-PHE-SER-ALA-ARG | Fibrinopeptide BA

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Fibrin formation is an essential part in wound healing and inflammation. Fibrinopeptide B (FPB) can also cause chemotactic migration of neutrophils, without the simultaneous release of lysosome enzymes.It is produced during the coagulation of fibrinogen,

Sequence

Glu-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg

CAS

103213-49-6(free)

Molecule Type

Peptide

Storage and Shipping

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • Class Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• Class: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Peptides Arginine and derivatives Phenylalanine and derivatives Pentacarboxylic acids and derivatives Glutamic acid and derivatives Asparagine and derivatives Aspartic acid and derivatives N-acyl-L-alpha-amino acids Valine and derivatives Serine and derivatives Alpha amino acid amides Alanine and derivatives Amphetamines and derivatives Amino fatty acids Hydroxy fatty acids N-acyl amines Secondary carboxylic acid amides Primary carboxylic acid amides Amino acids Guanidines Carboxylic acids Carboximidamides Primary alcohols Hydrocarbon derivatives Imines Monoalkylamines Organic oxides Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Polypeptide - Alpha peptide - Phenylalanine or derivatives - Arginine or derivatives - Pentacarboxylic acid or derivatives - Glutamic acid or derivatives - Aspartic acid or derivatives - Asparagine or derivatives - N-acyl-alpha amino acid or derivatives - Valine or derivatives - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - Alpha-amino acid amide - Serine or derivatives - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Hydroxy fatty acid - Amino fatty acid - Fatty amide - N-acyl-amine - Monocyclic benzene moiety - Fatty acyl - Benzenoid - Amino acid or derivatives - Amino acid - Carboxamide group - Secondary carboxylic acid amide - Guanidine - Primary carboxylic acid amide - Carboximidamide - Carboxylic acid derivative - Carboxylic acid - Organonitrogen compound - Organic oxide - Amine - Organic oxygen compound - Carbonyl group - Alcohol - Hydrocarbon derivative - Organic nitrogen compound - Imine - Primary aliphatic amine - Primary amine - Primary alcohol - Organooxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y