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Synonyms
1H-Indole-3-carbonitrile,2-amino-6-[2-(3-fluorophenyl)ethenyl]-
Shipped In
Ice chest + Ice pads
Overview Information
GSK2643943A is an inhibitor ofdeubiquitylating enzyme (DUB)with IC50 of 160 nM forUSP20/Ub-Rho.
Targets
USP20/Ub-Rho (Cell-free assay) 160 nM
Specifications Synonyms
1H-Indole-3-carbonitrile, 2-amino-6-[2-(3-fluorophenyl)ethenyl]-
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties ALogP 3.571 HBD Count 2 Rotatable Bond 2
Names and Identifiers Pubchem Sid 504773490 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504773490 Canonical Smiles C1=CC(=CC(=C1)F)C=CC2=CC3=C(C=C2)C(=C(N3)N)C#N IUPAC Name 2-amino-6-[(E)-2-(3-fluorophenyl)ethenyl]-1H-indole-3-carbonitrile InChIKey CGXBPMZRTMXEIA-SNAWJCMRSA-N INCHI 1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+ Molecular Weight 277.3 Reaxy-Rn 38910864 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38910864&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
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Advanced Data 3D Structure Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 55 mg/mL (198.34 mM); Ethanol: 8 mg/mL (28.84 mM); Water: Insoluble; DMSO(mg / mL) Max Solubility 55 DMSO(mM) Max Solubility 198.341146772449 Water(mg / mL) Max Solubility ＜1 Molecular Weight 277.290 g/mol XLogP3 4.300 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 2 Exact Mass 277.102 Da Monoisotopic Mass 277.102 Da Topological Polar Surface Area 65.600 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 441.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
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