Kuwanon G - ≥99% , CAS No.75629-19-5

CAS: 75629-19-5 Cat. No.: K650191 Molecular Weight: 692.71 PubChem CID: 5281667

GRADE & PURITY ≥99%

Synonyms

GQ6QVK8YZM | 8-[(1S,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one | 4H-1-Benzopyran-4-one, 8-[6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-m

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Kuwanon G is a flavonoid isolated from Morus alba , acts as a bombesin receptor antagonist, with potential antimicrobial activity.

Form:Solid

Specifications

Synonyms

GQ6QVK8YZM | 8-[(1S, 6S)-6-(2, 4-dihydroxybenzoyl)-5-(2, 4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2, 4-dihydroxyphenyl)-5, 7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one | 4H-1-Benzopyran-4-one, 8-[6-(2, 4-dihydroxybenzoyl)-5-(2, 4-dihydroxyphenyl)-3-m

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Kuwanon G is a flavonoid isolated from Morus alba , acts as a bombesin receptor antagonist, with potential antimicrobial activity.

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CC1=CC(C(C(C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C=C(C5=C4OC(=C(C5=O)CC=C(C)C)C6=C(C=C(C=C6)O)O)O)O
• IUPAC Name: 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one
• InChIKey: APPXYONGBIXGRO-AIQWNVMPSA-N
• INCHI: 1S/C40H36O11/c1-18(2)4-8-26-38(50)36-33(48)17-32(47)35(40(36)51-39(26)25-11-7-22(43)16-31(25)46)28-13-19(3)12-27(23-9-5-20(41)14-29(23)44)34(28)37(49)24-10-6-21(42)15-30(24)45/h4-7,9-11,13-17,27-28,34,41-48H,8,12H2,1-3H3/t27-,28-,34-/m0/s1
• Isomeric SMILES: CC1=C[C@@H]([C@H]([C@@H](C1)C2=C(C=C(C=C2)O)O)C(=O)C3=C(C=C(C=C3)O)O)C4=C(C=C(C5=C4OC(=C(C5=O)CC=C(C)C)C6=C(C=C(C=C6)O)O)O)O
• PubChem CID: 5281667
• Molecular Weight: 692.71

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Class Flavonoids
      • Subclass Flavones

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Class: Flavonoids
• Subclass: Flavones
• Intermediate Tree Nodes: Not available
• Direct Parent: 8-prenylated flavones
• Alternative Parents: 3-prenylated flavones Linear diarylheptanoids 4'-hydroxyflavonoids 5-hydroxyflavonoids 7-hydroxyflavonoids Alkyl-phenylketones Chromones Benzoyl derivatives Aryl alkyl ketones Resorcinols 1-hydroxy-2-unsubstituted benzenoids Pyranones and derivatives 1-hydroxy-4-unsubstituted benzenoids Heteroaromatic compounds Vinylogous acids Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-prenylated flavone - 8-prenylated flavone - Linear 1,7-diphenylheptane skeleton - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Hydroxyflavonoid - Alkyl-phenylketone - Chromone - Benzopyran - 1-benzopyran - Phenylketone - Aryl alkyl ketone - Aryl ketone - Benzoyl - Resorcinol - 1-hydroxy-4-unsubstituted benzenoid - Phenol - Pyranone - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Pyran - Vinylogous acid - Heteroaromatic compound - Ketone - Oxacycle - Organoheterocyclic compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 8-prenylated flavones. These are flavones that features a C5-isoprenoid substituent at the 8-position.
• External Descriptors: flavones

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Gusb Beta-glucuronidase (17 Activities)

Discover Target: Gusb

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO : 50 mg/mL (72.18 mM; Need ultrasonic)
• Molecular Weight: 692.700 g/mol
• XLogP3: 7.300
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 7
• Exact Mass: 692.226 Da
• Monoisotopic Mass: 692.226 Da
• Topological Polar Surface Area: 205.000 Ų
• Heavy Atom Count: 51
• Formal Charge: 0
• Complexity: 1380.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1