Leucomalachite Green - 10mM in DMSO , CAS No.129-73-7

CAS: 129-73-7 Cat. No.: L421166 Molecular Weight: 330.47 Beilstein Registry Number: 2140506 EC Number: 204-961-9
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GRADE & PURITY 10mM in DMSO
Synonyms
4,4'-(Phenylmethylene)bis(N,N-dimethylbenzenamine) | CCRIS 8665 | Leucomalachite Green, certified reference material, TraceCERT(R) | MalachitgrA(1/4)n | Tox21_302103 | 4-13-00-00481 (Beilstein Handbook Reference) | B0419 | AI3-22125 | beta-cyclopentyl-dl-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
L421166-1ml
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Leucomalachite Green is a triphenylmethane dye used to detect blood. A method for testing for the presence of leucomalachite green utilizing SDS-modified maghemite nanoparticles (γ-Fe(2)O(3)) has been described. Other studies have reported various protocols useful for determining the presence of Leucomalachite green in aquatic biological systems.

Specifications

Synonyms
4, 4'-(Phenylmethylene)bis(N, N-dimethylbenzenamine) | CCRIS 8665 | Leucomalachite Green, certified reference material, TraceCERT(R) | MalachitgrA(1/4)n | Tox21_302103 | 4-13-00-00481 (Beilstein Handbook Reference) | B0419 | AI3-22125 | beta-cyclopentyl-dl-
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Canonical SmilesCN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
IUPAC Name4-[[4-(dimethylamino)phenyl]-phenylmethyl]-N,N-dimethylaniline
InChIKeyWZKXBGJNNCGHIC-UHFFFAOYSA-N
INCHI1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
Isomeric SMILES CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
WGK Germany 3
RTECS CY1203055
UN Number 3077
Molecular Weight 330.47
Beilstein 2140506
Reaxy-Rn 2140506
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2140506&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassTriphenyl compounds
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentTriphenyl compounds
Alternative Parents Dialkylarylamines  Aniline and substituted anilines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Triphenyl compound - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Monocyclic benzene moiety - Tertiary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SensitivityLight & Air Sensitive
Melt Point(°C)100-102°C
Molecular Weight330.500 g/mol
XLogP35.300
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass330.21 Da
Monoisotopic Mass330.21 Da
Topological Polar Surface Area6.500 Ų
Heavy Atom Count25
Formal Charge0
Complexity342.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim.  (2023)  Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance.  MEDICAL PHYSICS,  50  (10): (6624-6636).  [PMID:37408321] [10.1002/mp.16541]
2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang.  (2023)  SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots.  FOOD CHEMISTRY,      [PMID:37245470] [10.1016/j.foodchem.2023.136443]
3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang.  (2023)  A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2023.108629]
4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang.  (2022)  Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I.  JOURNAL OF FOOD AND DRUG ANALYSIS,      [PMID:] [10.38212/2224-6614.3422]
5. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong.  (2021)  Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe.  JOURNAL OF CHEMICAL SCIENCES,  133  (2): (1-8).  [PMID:] [10.1007/s12039-021-01913-6]
6. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim.  (2020)  Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine.  PLoS One,  15  (3): (e0230410).  [PMID:32176733] [10.1371/journal.pone.0230410]
7. Yaoping Hu, Zhijin Gao.  (2020)  Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:31968303] [10.1016/j.jhazmat.2020.122073]
8. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang.  (2019)  Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere.  MARINE POLLUTION BULLETIN,      [PMID:32056604] [10.1016/j.marpolbul.2019.110812]
9. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao.  (2019)  Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green.  CHEMOSPHERE,      [PMID:31527004] [10.1016/j.chemosphere.2019.124764]
10. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang.  (2019)  Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites.  Nanomaterials,  (2): (229).  [PMID:30744009] [10.3390/nano9020229]
11. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang.  (2018)  Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction.  TALANTA,      [PMID:30029423] [10.1016/j.talanta.2018.06.040]
12. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang.  (2018)  Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2018.03.057]
13. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang.  (2018)  Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:29438941] [10.1016/j.saa.2018.02.016]
14. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong.  (2018)  Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles.  Food Analytical Methods,  11  (6): (1668-1676).  [PMID:] [10.1007/s12161-017-1144-3]
15. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi.  (2016)  Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  408  (22): (6223-6233).  [PMID:27382971] [10.1007/s00216-016-9737-z]
16. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu.  (2015)  Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence.  TALANTA,      [PMID:26003716] [10.1016/j.talanta.2015.04.053]
17. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang.  (2014)  An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green.  RSC Advances,  (105): (60987-60994).  [PMID:] [10.1039/C4RA09850A]
18. Jin Dong Cho, Chang Heon Choi, Heerim Nam, Jung-in Kim.  (2024)  Improved sensitivity and ambient light stability of radiochromic plastic dosimeters through composite azo compounds.  RADIATION PHYSICS AND CHEMISTRY,      [PMID:] [10.1016/j.radphyschem.2024.111891]
19. Guo Dongying, Yang Hailiang, Zhang Longyue, Dai Ruoyu, Huang Yuankui, Hu Yaoping.  (2025)  Smartphone-assisted detection of methylene blue using leaf-derived, dual-emissive carbon dots as ratiometric fluorescence probes.  MICROCHIMICA ACTA,  192  (3): (1-9).  [PMID:39930302] [10.1007/s00604-025-07022-2]
20. Jia Wang, Chen Zhao, Chengyi Hong, Zhengzhong Lin, Zhiyong Huang.  (2021)  Rapid detection of malachite green in fish and water based on the peroxidase-like activity of Fe3O4NPs enhanced with aptamer.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2021.104162]
21. Chen Ling, Shao Keman, Xu Jiajia, Wang Xiwen, Huang Zhenwei, Lin Zhengzhong.  (2025)  ‌Discrimination of Triphenylmethane Drug in Aquatic Products Using Fluorescence Sensor Array Based on Rare-Earth Complexes‌.  JOURNAL OF FLUORESCENCE,      [PMID:41467929] [10.1007/s10895-025-04692-2]
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