Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Levofloxacin Hydrochloride is a fluoroquinolone broad spectrum antibiotic. It is an inhibitor of two enzymes, DNA gyrase and topoisomerase IV.
| Pubchem Sid | 504765075 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765075 |
| Canonical Smiles | CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl |
| IUPAC Name | (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrochloride |
| InChIKey | CAOOISJXWZMLBN-PPHPATTJSA-N |
| INCHI | 1S/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1 |
| Isomeric SMILES | C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl |
| Molecular Weight | 397.83 |
| Reaxy-Rn | 8527394 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8527394&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Quinolines and derivatives |
| Subclass | Quinoline carboxylic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinoline carboxylic acids |
| Alternative Parents | Fluoroquinolones N-arylpiperazines Haloquinolines Aminoquinolines and derivatives Hydroquinolones Benzoxazines Hydroquinolines Pyridinecarboxylic acids Dialkylarylamines Alkyl aryl ethers N-methylpiperazines Benzenoids Aryl fluorides Heteroaromatic compounds Vinylogous amides Trialkylamines Amino acids Oxacyclic compounds Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Hydrochlorides Organic oxides Organofluorides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Benzoxazine - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Alkyl aryl ether - N-methylpiperazine - N-alkylpiperazine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Benzenoid - Vinylogous amide - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Amino acid - Azacycle - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Ether - Organic nitrogen compound - Hydrocarbon derivative - Organohalogen compound - Organofluoride - Organic oxide - Amine - Hydrochloride - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 12, 2025 | L305201 | |
| Certificate of Analysis | Jul 12, 2025 | L305201 | |
| Certificate of Analysis | Jul 12, 2025 | L305201 | |
| Certificate of Analysis | Jul 12, 2025 | L305201 | |
| Certificate of Analysis | Jul 12, 2025 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Aug 30, 2024 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 | |
| Certificate of Analysis | Mar 19, 2022 | L305201 |
| Solubility | Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
|---|---|
| Sensitivity | Air sensitive;Moisture sensitive |
| Flash Point(°C) | 299.4°C |
| Boil Point(°C) | 571.5°C |
| Molecular Weight | 397.800 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 2 |
| Exact Mass | 397.12 Da |
| Monoisotopic Mass | 397.12 Da |
| Topological Polar Surface Area | 73.300 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 634.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Xiaojing Qin, Rongrong Tao, Song Cheng, Baolin Xing, Weibo Meng, Yanhe Nie, Chuanxiang Zhang, Jianglong Yu. (2023) Microwave-assisted one-pot method preparation of ZnO decorated biochar for levofloxacin and Cr(Ⅵ) removal from wastewater. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2023.117863] |
| 2. Xiaoting Yu, Fengfan Zhu, Boyi Yang, Jiancheng Zhou, Ke Wang, Nan Wang, Naixu Li. (2023) Novel BiVO4/SiC/Cu2O ternary composite photocatalyst coupled with carbonized wood for simultaneous water evaporation and purification driven by solar energy. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.124307] |
| 3. Bing Liu, Xia Zhang, Jialong Chu, Fei Li, Caixia Jin, Jing Fan. (2023) 2D/2D BiOIO3/Ti3C2 MXene nanocomposite with efficient charge separation for degradation of multiple pollutants. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2023.156565] |
| 4. Lu Min, Liu Bingxin, Xiong Wenbin, Liu Xinchun. (2022) The Combination of Salmonella Phage ST-3 and Antibiotics to Prevent Salmonella Typhimurium In Vitro. CURRENT MICROBIOLOGY, 79 (12): (1-10). [PMID:36269452] [10.1007/s00284-022-03073-3] |
| 5. Yanzhuo Zhang, Jing Zhao. (2022) Comparison of different S-doped biochar materials to activate peroxymonosulfate for efficient degradation of antibiotics. CHEMOSPHERE, [PMID:36126742] [10.1016/j.chemosphere.2022.136442] |
| 6. Xin-Yuan Jiang, Zong-Yi Ren, Nian-Kun Zhang, Ke-Chen Yang, Gao-Xue Wang, Hai-Feng Jiang. (2022) Screening and evaluating honokiol from Magnolia officinalis against Nocardia seriolae infection in largemouth bass (Micropterus Salmoides). JOURNAL OF FISH DISEASES, 45 (11): (1599-1607). [PMID:35801398] [10.1111/jfd.13683] |
| 7. Yuan Qu, Heng Qian, Yiduo Mi, Jingjing He, Haixiang Gao, Runhua Lu, Sanbing Zhang, Wenfeng Zhou. (2020) Rapid determination of the pesticide ametryn based on a colorimetric aptasensor of gold nanoparticles. Analytical Methods, 12 (14): (1919-1925). [PMID:] [10.1039/D0AY00283F] |
| 8. Xiang Li, Lijuan Liang, Wei Xu, Shuangjiao Li, Shengbo Yuan, Haijuan Zhan, Wanyi Liu. (2025) Constructing a robust built-in electric field via adjusting the charge distribution from surface-to-bulk of phosphorus and benzene ring co-doped C3N5 for enhanced photocatalytic performance. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, [PMID:] [10.1016/j.jmst.2024.12.098] |
| 9. Mengyue Wang, Yu Wang, Nanjiong Pang, Mingyao Wang, Yunxiang He, Xiaoling Wang, Junling Guo. (2024) Efficient Removal of Tetracyclines and Quinolones Enabled by Polyphenol-Mediated Supramolecular Coagulation. LANGMUIR, [PMID:38320295] [10.1021/acs.langmuir.3c03261] |
| 10. Rui Fang, Ning Yu, Fa Wang, Xi Xu, Jianfa Zhang. (2025) Hemoadhican Fiber Composite with Carbon Dots for Treating Severe Hemorrhage and Infected Wounds. ACS Applied Materials & Interfaces, [PMID:39882714] [10.1021/acsami.4c20176] |
| 11. Wuxia Ge, Yumei Chen, Xinru Ding, Wentao Bi, David Da Yong Chen. (2025) Green synthesis of magnetic aromatic polyamide composites via mechanochemical ball milling with a deep eutectic system for the magnetic solid-phase extraction of antibiotics from water. JOURNAL OF CHROMATOGRAPHY A, [PMID:40043643] [10.1016/j.chroma.2025.465830] |
| 12. Jingjing Wang, Waqas Ahmad, Yuzhen Liang, Yi Xu, Tianhui Jiao, Peipei Qi, Xingyu Lin, Quansheng Chen. (2025) Electrochemical synthesis of ultra-compact gold hexagonal nanostar substrate for enhanced and stable SERS detection. ANALYTICA CHIMICA ACTA, [PMID:41285526] [10.1016/j.aca.2025.344779] |
| 13. Kaixin Sun, Bo Gong, Chang Xu, Shan Zhao, Shuguang Wang, Le Ren, Chao Song. (2025) Enhancing the degradation of ciprofloxacin and levofloxacin by peroxydisulfate (PDS): Multiple roles of co-existing copper ion. Journal of Environmental Chemical Engineering, 13 (6): (120491). [PMID:] [10.1016/j.jece.2025.120491] |