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Melanin-concentrating hormone receptor 1 (MCHR1)

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  1. GW 803430, Antagonist of MCH 1 receptor
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    GW 803430, Antagonist of MCH 1 receptor
    CAS: 515141-51-2 EC Number: 803-769-8 Formula: C₂₅H₂₄ClN₃O₃S Molecular Weight: 481.99
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: G287963
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    IUPAC Name
    6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]thieno[3,2-d]pyrimidin-4-one
    SMILES
    COC1=C(C=CC(=C1)N2C=NC3=C(C2=O)SC(=C3)C4=CC=C(C=C4)Cl)OCCN5CCCC5
    InChIKey
    MWULMTACIBZPGN-UHFFFAOYSA-N
    InChI
    1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3
    Synonyms
    DSS (Chemical Shape Indicator) | 2-chloro-5-chlorosulfonylbenzenesulfonamide | GW-803,430 | 6-(4-chlorophenyl)-3-[3-m...
  2. 2-Amino-8-quinolinol
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    2-Amino-8-quinolinol
    CAS: 70125-16-5 EC Number: 628-443-0 Formula: C9H8N2O Molecular Weight: 160.17
    ≥98%(GC)
    In Stock Item #: A136838
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    IUPAC Name
    2-aminoquinolin-8-ol
    SMILES
    C1=CC2=C(C(=C1)O)N=C(C=C2)N
    InChIKey
    UFVLIVCXTIGACT-UHFFFAOYSA-N
    InChI
    1S/C9H8N2O/c10-8-5-4-6-2-1-3-7(12)9(6)11-8/h1-5,12H,(H2,10,11)
    Synonyms
    A849428 | AKOS015919137 | AMY865 | SY122229 | 2-Amino-8-quinolinol, >=98.0% (GC) | UFVLIVCXTIGACT-UHFFFAOYSA-N | F116...
  3. MCHr1 antagonist 2
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    MCHr1 antagonist 2
    CAS: 863115-70-2 Formula: C23H21FN2O5 Molecular Weight: 424.42
    ≥98%
    In Stock Item #: M412388
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    IUPAC Name
    N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-6-fluoro-4-oxochromene-2-carboxamide
    SMILES
    C1CN(CCC1NC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)F)CC4=CC5=C(C=C4)OCO5
    InChIKey
    HHCYCBKPWYJVEB-UHFFFAOYSA-N
    InChI
    1S/C23H21FN2O5/c24-15-2-4-19-17(10-15)18(27)11-22(31-19)23(28)25-16-5-7-26(8-6-16)12-14-1-3-20-21(9-14)30-13-29-20/h1-4,9-11,16H,5-8,12-13H2,(H,25,28)
  4. TC-MCH 7c
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    TC-MCH 7c
    CAS: 864756-35-4 PubChem CID: 11654412 Formula: C24H25FN2O3 Molecular Weight: 408.47
    ≥97%(HPLC)
    In Stock Item #: T288362
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    IUPAC Name
    4-[(4-fluorophenyl)methoxy]-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyridin-2-one
    SMILES
    C1CCN(C1)CCOC2=CC=C(C=C2)N3C=CC(=CC3=O)OCC4=CC=C(C=C4)F
    InChIKey
    ANCFKYJMXNMYNZ-UHFFFAOYSA-N
    InChI
    1S/C24H25FN2O3/c25-20-5-3-19(4-6-20)18-30-23-11-14-27(24(28)17-23)21-7-9-22(10-8-21)29-16-15-26-12-1-2-13-26/h3-11,14,17H,1-2,12-13,15-16,18H2
    Synonyms
    4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone | 4-((4-fluorobenzyl)oxy)-1-(4-(2...
  5. no_selection
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    4-(cyclopropylmethoxy)-N-{3-[(1R)-1-[(2-acetamidoethyl)amino]ethyl]-8-methylquinolin-7-yl}benzamide, Antagonist of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C609517
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    IUPAC Name
    4-(cyclopropylmethoxy)-N-{3-[(1R)-1-[(2-acetamidoethyl)amino]ethyl]-8-methylquinolin-7-yl}benzamide
    SMILES
    CC(=O)NCCN[C@@H](c1cnc2c(c1)ccc(c2C)NC(=O)c1ccc(cc1)OCC1CC1)C
    InChIKey
    HRYQXLHGNOJEHH-GOSISDBHSA-N
    InChI
    1S/C27H32N4O3/c1-17-25(31-27(33)21-6-9-24(10-7-21)34-16-20-4-5-20)11-8-22-14-23(15-30-26(17)22)18(2)28-12-13-29-19(3)32/h6-11,14-15,18,20,28H,4-5,12-1show more
    Synonyms
    compound (R)-10h
  6. no_selection
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    7-fluorochromone-2-carboxamide, Antagonist of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: F607272
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    IUPAC Name
    N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-fluoro-4-oxochromene-2-carboxamide
    SMILES
    Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(CC1)Cc1ccc2c(c1)OCO2
    InChIKey
    FVFURMJFTAJXRH-UHFFFAOYSA-N
    InChI
    1S/C23H21FN2O5/c24-15-2-3-17-18(27)11-22(31-20(17)10-15)23(28)25-16-5-7-26(8-6-16)12-14-1-4-19-21(9-14)30-13-29-19/h1-4,9-11,16H,5-8,12-13H2,(H,25,28)
  7. no_selection
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    AZ13483342, Antagonist of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607834
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    Technical Identifiers
    IUPAC Name
    N-(6-methoxy-4-methylquinolin-2-yl)-N'-(thiophen-3-ylmethyl)propane-1,3-diamine
    SMILES
    COc1ccc2c(c1)c(C)cc(n2)NCCCNCc1cscc1
    InChIKey
    ZDKZIFSAJUTJSK-UHFFFAOYSA-N
    InChI
    1S/C19H23N3OS/c1-14-10-19(22-18-5-4-16(23-2)11-17(14)18)21-8-3-7-20-12-15-6-9-24-13-15/h4-6,9-11,13,20H,3,7-8,12H2,1-2H3,(H,21,22)
    Synonyms
    AZ 13483342;AZ-13483342
  8. LuAE51090
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    LuAE51090
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: L611603
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    IUPAC Name
    N-{1-[3-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide
    SMILES
    O=C(Cc1ccccc1)NC1CCN(CC1)CCCN1C(=O)COc2c1cccc2
    InChIKey
    FLGSUSWMWSZVMP-UHFFFAOYSA-N
    InChI
    1S/C24H29N3O3/c28-23(17-19-7-2-1-3-8-19)25-20-11-15-26(16-12-20)13-6-14-27-21-9-4-5-10-22(21)30-18-24(27)29/h1-5,7-10,20H,6,11-18H2,(H,25,28)
    Synonyms
    compound 6;Lu AE51090
  9. no_selection
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    MQ1, Allosteric modulator of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: M612012
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    Technical Identifiers
    IUPAC Name
    4-(cyclopropylmethoxy)-N-[8-methyl-3-[(1R)-1-pyrrolidin-1-ylethyl]quinolin-7-yl]benzamide
    SMILES
    O=C(c1ccc(cc1)OCC1CC1)Nc1ccc2c(c1C)ncc(c2)[C@H](N1CCCC1)C
    InChIKey
    DFWKNBVJNXPUBW-LJQANCHMSA-N
    InChI
    1S/C27H31N3O2/c1-18-25(29-27(31)21-7-10-24(11-8-21)32-17-20-5-6-20)12-9-22-15-23(16-28-26(18)22)19(2)30-13-3-4-14-30/h7-12,15-16,19-20H,3-6,13-14,17H2show more
    Synonyms
    compound (R)-10a;MQ-1
  10. no_selection
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    T-226296, Antagonist of MCH 1 receptor
    CAS: 331758-35-1 PubChem CID: 9865843
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: T614293
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    Technical Identifiers
    IUPAC Name
    N-[6-(dimethylaminomethyl)-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)benzamide
    SMILES
    CN(CC1CCc2c(C1)ccc(c2)NC(=O)c1ccc(cc1)c1ccc(cc1)F)C
    InChIKey
    GXAQELJVODWLDD-UHFFFAOYSA-N
    InChI
    1S/C26H27FN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30)
    Synonyms
    T 226296;T226296
  11. no_selection
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    pyrrolidine MCHR1 antagonist 1, Antagonist of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: P613030
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    IUPAC Name
    N-(3-chlorophenyl)-2-[(3R,4S)-1-[2-(4-hydroxyoxan-4-yl)ethyl]-4-(4-methoxyphenyl)pyrrolidin-3-yl]acetamide
    SMILES
    COc1ccc(cc1)[C@H]1CN(C[C@@H]1CC(=O)Nc1cccc(c1)Cl)CCC1(O)CCOCC1
    InChIKey
    OLINDOIRFAZHRH-GBXCKJPGSA-N
    InChI
    1S/C26H33ClN2O4/c1-32-23-7-5-19(6-8-23)24-18-29(12-9-26(31)10-13-33-14-11-26)17-20(24)15-25(30)28-22-4-2-3-21(27)16-22/h2-8,16,20,24,31H,9-15,17-18H2,show more
  12. no_selection
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    4-arylphthalazin-1(2H)-3,4-Di-F, Antagonist of MCH 1 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607182
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    Technical Identifiers
    IUPAC Name
    N-[3-(1-{3-[4-(3,4-difluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]propyl}piperidin-4-yl)phenyl]acetamide
    SMILES
    CC(=O)Nc1cccc(c1)C1CCN(CC1)CCCn1nc(c2ccc(c(c2)F)F)c2c(c1=O)cccc2
    InChIKey
    YVVMAGRTTSOPEO-UHFFFAOYSA-N
    InChI
    1S/C30H30F2N4O2/c1-20(37)33-24-7-4-6-22(18-24)21-12-16-35(17-13-21)14-5-15-36-30(38)26-9-3-2-8-25(26)29(34-36)23-10-11-27(31)28(32)19-23/h2-4,6-11,18-show more
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