Mitogen-activated protein kinase 10 (MAPK10)

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  1. SR 3576
    CAS: 1164153-22-3 PubChem CID: 70702008 Formula: C27H27N5O5 Molecular Weight: 501.54
    In Stock Item #: S275279
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    IUPAC Name
    3-[4-[(3-methylphenyl)carbamoylamino]pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide
    SMILES
    CC1=CC(=CC=C1)NC(=O)NC2=CN(N=C2)C3=CC=CC(=C3)C(=O)NC4=CC(=C(C(=C4)OC)OC)OC
    InChIKey
    MTFAYLZZDJGFGV-UHFFFAOYSA-N
    InChI
    1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33show more
    Synonyms
    3-[4-[(3-methylphenyl)carbamoylamino]pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide | 3-(4-(3-m-tolylureido)-1H-py...
  2. SGX-523, Hepatocyte growth factor receptor inhibitor
    CAS: 1022150-57-7 PubChem CID: 24779724 Formula: C18H13N7S Molecular Weight: 359.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S127194
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    IUPAC Name
    6-[[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl]quinoline
    SMILES
    CN1C=C(C=N1)C2=NN3C(=NN=C3SC4=CC5=C(C=C4)N=CC=C5)C=C2
    InChIKey
    BCZUAADEACICHN-UHFFFAOYSA-N
    InChI
    1S/C18H13N7S/c1-24-11-13(10-20-24)16-6-7-17-21-22-18(25(17)23-16)26-14-4-5-15-12(9-14)3-2-8-19-15/h2-11H,1H3
    Synonyms
    6-((6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)quinoline | AKOS025117577 | NCGC00263163-0...
  3. SP600125, Inhibitor of mitogen-activated protein kinase 10;Inhibitor of mitogen-activated protein kinase 8;Inhibitor of mitogen-activated protein kinase 9
    CAS: 129-56-6 EC Number: 204-955-6 PubChem CID: 8515 Formula: C14H8N2O Molecular Weight: 220.233
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S125267
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    IUPAC Name
    14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one
    SMILES
    C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
    InChIKey
    ACPOUJIDANTYHO-UHFFFAOYSA-N
    InChI
    1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
    Synonyms
    HMS1362F07 | KBioGR_000406 | Anthra[1-9-cd]pyrazol-6(2H)-one | SDCCGSBI-0050458.P003 | WLN: T C66651A P IV OMNJ | Pyr...
  4. SB-203580, Inhibitor of cyclin G associated kinase;Inhibitor of mitogen-activated protein kinase 11;Inhibitor of mitogen-activated protein kinase 14
    CAS: 152121-47-6 EC Number: 688-252-3 PubChem CID: 176155 Formula: C21H16FN3OS Molecular Weight: 377.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S131899
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    IUPAC Name
    4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
    SMILES
    CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
    InChIKey
    CDMGBJANTYXAIV-UHFFFAOYSA-N
    InChI
    1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
    Synonyms
    ES-0013 | RWJ64809 | RWJ-64809 | CHEBI:90705 | UNII-OU13V1EYWQ | J-008891 | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfiny...
  5. PND-1186, Focal adhesion kinase 1 inhibitor
    CAS: 1061353-68-1 Formula: C25H26F3N5O3 Molecular Weight: 501.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P126394
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    IUPAC Name
    2-[[2-(2-methoxy-4-morpholin-4-ylanilino)-5-(trifluoromethyl)pyridin-4-yl]amino]-N-methylbenzamide
    SMILES
    CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=C(C=C(C=C3)N4CCOCC4)OC
    InChIKey
    IGUBBWJDMLCRIK-UHFFFAOYSA-N
    InChI
    1S/C25H26F3N5O3/c1-29-24(34)17-5-3-4-6-19(17)31-21-14-23(30-15-18(21)25(26,27)28)32-20-8-7-16(13-22(20)35-2)33-9-11-36-12-10-33/h3-8,13-15H,9-12H2,1-2show more
    Synonyms
    2-((2-((2-methoxy-4-morpholinophenyl)amino)-5-(trifluoromethyl)pyridin-4-yl)amino)-N-methylbenzamide. | Q27089163 | S...
  6. BI 78D3
    CAS: 883065-90-5 Formula: C13H9N5O5S2 Molecular Weight: 379.37
    In Stock Item #: B286827
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    IUPAC Name
    4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one
    SMILES
    C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
    InChIKey
    QFRLDZGQEZCCJZ-UHFFFAOYSA-N
    InChI
    1S/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19)
    Synonyms
    NCGC00263145-01 | BDBM26057 | BCP17200 | 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-...
  7. AS601245, Inhibitor of mitogen-activated protein kinase 10
    CAS: 345987-15-7 Formula: C20H16N6S Molecular Weight: 372.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A275935
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    IUPAC Name
    2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
    SMILES
    C1=CC=C2C(=C1)N=C(S2)C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4
    InChIKey
    RCYPVQCPYKNSTG-UHFFFAOYSA-N
    InChI
    1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,15H,7,10H2,(H,23,24,26)
    Synonyms
    VNA98715 | HY-11010 | Q27163222 | 2-(4-dimethylaminophenyl)-1h-benzimidazole | 2-Benzothiazoleacetonitrile, alpha-(2-...
  8. TAE226 (NVP-TAE226), Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor;Inhibitor of protein tyrosine kinase 2;Inhibitor of protein tyrosine kinase 2 beta
    CAS: 761437-28-9 PubChem CID: 9934347 Formula: C23H25ClN6O3 Molecular Weight: 468.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: T129808
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    IUPAC Name
    2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide
    SMILES
    CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCOCC4)OC
    InChIKey
    UYJNQQDJUOUFQJ-UHFFFAOYSA-N
    InChI
    1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,show more
    Synonyms
    BCP06482 | FT-0700360 | HMS3672E03 | 2-[5-chloro-2-(2-methoxy-4-morpholin-4-yl-phenylamino)-pyrimidin-4-ylamino]-N-me...
  9. Ethyl 1H-indazole-3-carboxylate
    CAS: 4498-68-4 Formula: C10H10N2O2 Molecular Weight: 190.20
    In Stock Item #: E133712
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    IUPAC Name
    ethyl 1H-indazole-3-carboxylate
    SMILES
    CCOC(=O)C1=NNC2=CC=CC=C21
    InChIKey
    YLKPTYMNELPKOL-UHFFFAOYSA-N
    InChI
    1S/C10H10N2O2/c1-2-14-10(13)9-7-5-3-4-6-8(7)11-12-9/h3-6H,2H2,1H3,(H,11,12)
    Synonyms
    1H-lndazole-3-carboxylic acid ethyl ester | NSC 179807 | 4-Hydroxy-3-methylaniline | J-521296 | 1H-Indazole-3-carboxy...
  10. TCS JNK 5a, Inhibitor of mitogen-activated protein kinase 10;Inhibitor of mitogen-activated protein kinase 9
    CAS: 312917-14-9 PubChem CID: 766949 Formula: C20H16N2OS Molecular Weight: 332.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    In Stock Item #: T287056
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    IUPAC Name
    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)naphthalene-1-carboxamide
    SMILES
    C1CCC2=C(C1)C(=C(S2)NC(=O)C3=CC=CC4=CC=CC=C43)C#N
    InChIKey
    WQGDQGAFSDMBLA-UHFFFAOYSA-N
    InChI
    1S/C20H16N2OS/c21-12-17-15-9-3-4-11-18(15)24-20(17)22-19(23)16-10-5-7-13-6-1-2-8-14(13)16/h1-2,5-8,10H,3-4,9,11H2,(H,22,23)
    Synonyms
    N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide, TCS JNK 5a | C20H16N2OS | EX-A543 | N-(3...
  11. TCS JNK 6o, Inhibitor of mitogen-activated protein kinase 10;Inhibitor of mitogen-activated protein kinase 8;Inhibitor of mitogen-activated protein kinase 9
    CAS: 894804-07-0 PubChem CID: 11624601 Formula: C18H20N4O4 Molecular Weight: 356.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: T288865
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    IUPAC Name
    N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
    SMILES
    CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N
    InChIKey
    KQMPRSZTUSSXND-UHFFFAOYSA-N
    InChI
    1S/C18H20N4O4/c1-4-26-18-13(10-19)14(20)9-16(22-18)21-17(23)8-11-7-12(24-2)5-6-15(11)25-3/h5-7,9H,4,8H2,1-3H3,(H3,20,21,22,23)
    Synonyms
    aminopyridine deriv. 2 | CCG-206859 | Aminopyridine-Based Inhibitor 6o | s7794 | JNK inhibitor compound 6o | N-(4-Ami...
  12. SB 202190, Inhibitor of mitogen-activated protein kinase 14
    CAS: 152121-30-7 EC Number: 633-977-2 PubChem CID: 5169 Formula: C20H14FN3O Molecular Weight: 331.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: S134307
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    IUPAC Name
    4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol
    SMILES
    C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O
    InChIKey
    QHKYPYXTTXKZST-UHFFFAOYSA-N
    InChI
    1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)
    Synonyms
    FHPI | SB 202190 | 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole | 4-(4-(4-fluorophenyl)-5-(pyrid...
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