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Tyrosine-protein kinase syk (SYK)

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  1. ACHP
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    ACHP
    CAS: 406208-42-2 Formula: C21H24N4O2 Molecular Weight: 364.44
    ≥97%(HPLC)
    In Stock Item #: A288136
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    Technical Identifiers
    IUPAC Name
    2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-piperidin-4-ylpyridine-3-carbonitrile
    SMILES
    C1CC1COC2=CC=CC(=C2C3=NC(=C(C(=C3)C4CCNCC4)C#N)N)O
    InChIKey
    DYVFBWXIOCLHPP-UHFFFAOYSA-N
    InChI
    1S/C21H24N4O2/c22-11-16-15(14-6-8-24-9-7-14)10-17(25-21(16)23)20-18(26)2-1-3-19(20)27-12-13-4-5-13/h1-3,10,13-14,24,26H,4-9,12H2,(H2,23,25)
    Synonyms
    2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-(4-piperidinyl)-3-pyridine-carbonitrile | 2-amino-6-[2-(cyclopro...
  2. Syk Inhibitor IV, BAY 61-3606 HCl - ≥97%, used for , CAS No. 732983-37-8, by Aladdin Scientific
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    BAY 61-3606, Inhibitor of component of inhibitor of nuclear factor kappa B kinase complex;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of spleen associated tyrosine kinase
    CAS: 732983-37-8 Formula: C20H18N6O3 Molecular Weight: 390.40
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: S340911
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    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC
    InChIKey
    JWQOJVOKBAAAAR-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19/h3-11H,1-2H3,(H2,21,27)(H,23,24,25)
    Synonyms
    Kinome_3125 | BAY-61-360 | UNII-61G8S0H9KX | BAY 61-3606 free base | CCG-102604 | AT32059 | BAY-61-3606 free base | D...
  3. Fostamatinib Disodium Hexahydrate, Tyrosine-protein kinase SYK inhibitor
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    Fostamatinib Disodium Hexahydrate, Tyrosine-protein kinase SYK inhibitor
    CAS: 914295-16-2 EC Number: 682-713-2 Formula: C23H36FN6Na2O15P Molecular Weight: 732.51
    ≥98%
    In Stock Item #: F336802
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    IUPAC Name
    disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate;hexahydrate
    SMILES
    CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
    InChIKey
    ZQGJCHHKJNSPMS-UHFFFAOYSA-L
    InChI
    1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;show more
    Synonyms
    Fostamatinib disodium | Fostamatinib disodium [USAN] | Fostamatinib disodium hexahydrate | R-935788 | Tamatinib fosdi...
  4. Phenylmalonic acid
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    Phenylmalonic acid
    CAS: 2613-89-0 EC Number: 220-044-6 Formula: C9H8O4 Molecular Weight: 180.16
    ≥98%
    In Stock Item #: P113809
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    Technical Identifiers
    IUPAC Name
    2-phenylpropanedioic acid
    SMILES
    C1=CC=C(C=C1)C(C(=O)O)C(=O)O
    InChIKey
    WWYDYZMNFQIYPT-UHFFFAOYSA-N
    InChI
    1S/C9H8O4/c10-8(11)7(9(12)13)6-4-2-1-3-5-6/h1-5,7H,(H,10,11)(H,12,13)
    Synonyms
    alpha-Carboxyphenylacetic acid | Phenylpropanedioc acid | .alpha.-Carboxyphenylacetic acid | 92EX195E1G | 1H-Pyrazol-...
  5. Bay 61-3606 hydrochloride
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    Bay 61-3606 hydrochloride
    CAS: 732983-37-8 Formula: C20H18N6O3 Molecular Weight: 390.40
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: B275245
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC
    InChIKey
    JWQOJVOKBAAAAR-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19/h3-11H,1-2H3,(H2,21,27)(H,23,24,25)
    Synonyms
    2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamidehydrochloride
  6. Fostamatinib (R788), Tyrosine-protein kinase SYK inhibitor
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    Fostamatinib (R788), Tyrosine-protein kinase SYK inhibitor
    CAS: 901119-35-5 EC Number: 618-473-2 Formula: C23H26FN6O9P Molecular Weight: 580.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F129915
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    Technical Identifiers
    IUPAC Name
    [6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate
    SMILES
    CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
    InChIKey
    GKDRMWXFWHEQQT-UHFFFAOYSA-N
    InChI
    1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11Hshow more
    Synonyms
    J-517972 | FOSTAMATINIB [INN] | (6-((5-Fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-o...
  7. TH 257
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    TH 257
    CAS: 2244678-29-1 PubChem CID: 137796294 Formula: C24H26N2O3S Molecular Weight: 422.54
    ≥98%(HPLC)
    In Stock Item #: T287707
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    IUPAC Name
    N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide
    SMILES
    CCCCN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3
    InChIKey
    VNCIWNGCMAKKEO-UHFFFAOYSA-N
    InChI
    1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3
    Synonyms
    N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
  8. Tyrphostin 47
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    Tyrphostin 47
    CAS: 122520-86-9 PubChem CID: 667601 Formula: C10H8N2O2S Molecular Weight: 220.2
    ≥99%
    Out of Stock Item #: T275838
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    IUPAC Name
    (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide
    SMILES
    C1=CC(=C(C=C1C=C(C#N)C(=S)N)O)O
    InChIKey
    ZGHQGWOETPXKLY-XVNBXDOJSA-N
    InChI
    1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
    Synonyms
    NCGC00024619-01 | 3,4-Dihydroxy-alpha-cyanothiocinnamide | Tyrphostin 47 | AG 213 | HMS3402F14 | BiomolKI_000014 | ty...
  9. Aurora Kinase Inhibitor III, Inhibitor of aurora kinase A
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    Aurora Kinase Inhibitor III, Inhibitor of aurora kinase A
    CAS: 879127-16-9 Formula: C21H18F3N5O Molecular Weight: 413.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A426644
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    Technical Identifiers
    IUPAC Name
    N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
    SMILES
    C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
    InChIKey
    RDTDWGQDFJPTPD-UHFFFAOYSA-N
    InChI
    1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29show more
    Synonyms
    BDBM50200392 | D80989 | INH-1 | N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanec...
  10. Aurora Kinase Inhibitor III, Inhibitor of aurora kinase A
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    Aurora Kinase Inhibitor III, Inhibitor of aurora kinase A
    CAS: 879127-16-9 Formula: C21H18F3N5O Molecular Weight: 413.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A335095
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    Technical Identifiers
    IUPAC Name
    N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
    SMILES
    C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
    InChIKey
    RDTDWGQDFJPTPD-UHFFFAOYSA-N
    InChI
    1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29show more
    Synonyms
    BDBM50200392 | D80989 | INH-1 | N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanec...
  11. BAY-61-3606
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    BAY-61-3606
    CAS: 648903-57-5 PubChem CID: 11784504 Formula: C20H20Cl2N6O3 Molecular Weight: 463.32
    10mM in DMSO
    In Stock Item #: B425289
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide;dihydrochloride
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl
    InChIKey
    SPMFEULFGGPQLN-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);2*show more
    Synonyms
    MS-28520 | 2-(7-(3,4-Dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide dihydrochloride | BAY 61-3606 (di...
  12. BAY 61-3606 dihydrochloride
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    BAY 61-3606 dihydrochloride
    CAS: 648903-57-5 PubChem CID: 11784504 Formula: C20H20Cl2N6O3 Molecular Weight: 463.32
    ≥98%
    In Stock Item #: B413704
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide;dihydrochloride
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl
    InChIKey
    SPMFEULFGGPQLN-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);2*show more
    Synonyms
    MS-28520 | 2-(7-(3,4-Dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide dihydrochloride | BAY 61-3606 (di...
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