Minoxidil(U10858) - Moligand™, 10 mM in DMSO , CAS No.38304-91-5

CAS: 38304-91-5 Cat. No.: M1499315 Molecular Weight: 209.25 Beilstein Registry Number: 25(5)12,317 EC Number: 253-874-2

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Minoxidil (U10858) is an ATP-sensitive potassium (K ATP ) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC 50 of 20 μM.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
• WGK Germany: 3
• RTECS: UV8200000
• Molecular Weight: 209.25
• Beilstein: 25(5)12,317
• Reaxy-Rn: 656915
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=656915&ln=

Chemical and Physical Properties

• Melt Point(°C): 272-274 °C

References

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2. Yu Cai, Liying Xin, Hui Li, Peng Sun, Chao Liu, Liang Fang.  (2023)  Mussel-inspired controllable drug release hydrogel for transdermal drug delivery: Hydrogen bond and ion-dipole interactions.  JOURNAL OF CONTROLLED RELEASE,      [PMID:37972766] [10.1016/j.jconrel.2023.11.016]

3. Peixin Li, Yanfang Sun, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Yinjian Hua, Guohua Jiang.  (2023)  Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37517761] [10.1016/j.ijbiomac.2023.126013]

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6. Huanzhu Qian, Zhen Ye, Yu Hu, Liulin Chen, Linzhen Li, Kaihua Qin, Qiaobo Ye, Xiaohong Zuo.  (2025)  Dahuang-Gancao Decoction Ameliorates Testosterone-Induced Androgenetic Alopecia in Mice.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:39800247] [10.1016/j.jep.2025.119347]

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8. Yan-Wen Ding, Yang Li, Zhi-Wei Zhang, Jin-Wei Dao, Dai-Xu Wei.  (2024)  Hydrogel forming microneedles loaded with VEGF and Ritlecitinib/polyhydroxyalkanoates nanoparticles for mini-invasive androgenetic alopecia treatment.  Bioactive Materials,      [PMID:38699241] [10.1016/j.bioactmat.2024.04.020]

9. Shuting Zhang, Hong Zhou, Xuan Chen, Shasha Zhu, Dan Chen, Dan Luo, Siyuan Chen, Wei Liu.  (2024)  Microneedle Delivery Platform Integrated with Codelivery Nanoliposomes for Effective and Safe Androgenetic Alopecia Treatment.  ACS Applied Materials & Interfaces,      [PMID:38507687] [10.1021/acsami.3c16608]

10. Jiajia Wang, Yucen Cai, Lin Lei, Feng Zeng, Qi Liu, Yunqiang Xiang, Xinyuan Fu, Zhangyou Yang, Jing Luo.  (2025)  A mesoporous polydopamine-mediated programmed drug release hydrogel for burn wound treatment.  Materials Today Communications,      [PMID:] [10.1016/j.mtcomm.2025.113552]

11. Zheng Xing, Xiaoxiao Zhang, Chen Zhao, Li Zhang, Song Qian, Yun Chu, Wenhao Yang, Yuhui Wang, Jiang Xia, Jianhao Wang.  (2025)  Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia.  Acta Biomaterialia,      [PMID:40389048] [10.1016/j.actbio.2025.05.039]

12. Zheng Xing, Wenhao Yang, Chen Zhao, Yuhui Wang, Xiaolian Jiang, Song Qian, Yun Chu, Jiang Xia, Cheng Wang, Jianhao Wang.  (2025)  Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40398062] [10.1016/j.ijbiomac.2025.144460]

13. Zhiqing Liu, Wenhua Huang, Shanhua Xu, Meilan Nan, Xian Cui, Yue Wang, Zhehu Jin, Wan Meng, Jingbi Meng, Longquan Pi.  (2025)  Using a Natural Clay Mineral as an Active Drug Carrier to Promote Hair Growth.  Pharmaceuticals,  19  (1): (11).  [PMID:41599612] [10.3390/ph19010011]

14. Lingyun Zhao, Anqi Li, Shijing Chen, Wei Hua, Ru Dai, Lingyu Pan, Meng Hu, Nan Huang, Runke Zhou, Yuanyuan Han, Lidan Xiong, Li Li.  (2026)  Extracellular vesicles of human transformed skin-derived precursors containing miR-221-3p promote hair growth through DKK2-mediated Wnt/β-catenin signaling.  Bioengineering & Translational Medicine,      [PMID:] [10.1002/btm2.70130]

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