Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Mocetinostat (MGCD0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Phase 2.
A potent inhibitor of HDAC1, HDAC2, HDAC3, and HDAC11.
| ALogP | 2.8 |
|---|
| Pubchem Sid | 504765009 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765009 |
| Canonical Smiles | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4 |
| IUPAC Name | N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide |
| InChIKey | HRNLUBSXIHFDHP-UHFFFAOYSA-N |
| INCHI | 1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29) |
| Isomeric SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4 |
| Molecular Weight | 396.44 |
| Reaxy-Rn | 14262919 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14262919&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Anilides |
| Intermediate Tree Nodes | Aromatic anilides |
| Direct Parent | Benzanilides |
| Alternative Parents | Pyridinylpyrimidines Benzamides Aniline and substituted anilines Benzylamines Benzoyl derivatives Secondary alkylarylamines Aminopyrimidines and derivatives Pyridines and derivatives Heteroaromatic compounds Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Hydrocarbon derivatives Organic oxides Organooxygen compounds Organopnictogen compounds Primary amines |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Benzanilide - Pyridinylpyrimidine - Benzamide - Benzoic acid or derivatives - Benzoyl - Benzylamine - Aniline or substituted anilines - Aminopyrimidine - Secondary aliphatic/aromatic amine - Pyridine - Pyrimidine - Heteroaromatic compound - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Secondary amine - Organoheterocyclic compound - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene. |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 16, 2023 | M126151 |
| Solubility | DMSO 13 mg/mL (32.79 mM); Water <1 mg/mL (<1 mM); Ethanol <1 mg/mL (<1 mM) |
|---|---|
| Molecular Weight | 396.400 g/mol |
| XLogP3 | 2.800 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 6 |
| Exact Mass | 396.17 Da |
| Monoisotopic Mass | 396.17 Da |
| Topological Polar Surface Area | 106.000 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 538.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Si-Ke Chen, Da-Wei Pan, Zhuang Liu, Wei Wang, Rui Xie, Xiao-Ting Mu, Xiao-Jie Ju, Liang-Yin Chu. (2023) Microfluidic Fabrication of Calcium Alginate/Chitosan Composite Microcapsules with Ultrathin Shells for Peroxidase Immobilization. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, [PMID:] [10.1021/acs.iecr.3c01062] |
| 2. Wenfang Song, Hong Lu, Qiansheng Li, Xiaolei Wang, Ze Fu, Jiti Zhou. (2023) Aerobic degradation of ketoprofen by marine consortia: Fenton-like reaction and degradation pathway. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:37263434] [10.1016/j.scitotenv.2023.164520] |
| 3. Cong Pan, Wenyu Wang, Chenchong Fu, Jong Chol Nam, Feng Wu, Zhixiong You, Jing Xu, Jinjun Li. (2023) Promoted wet peroxide oxidation of chlorinated volatile organic compounds catalyzed by FeOCl supported on macro-microporous biomass-derived activated carbon. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:37201460] [10.1016/j.jcis.2023.05.004] |
| 4. Junpeng Yue, Hanpei Yang, Chen Liu, Qiang Zhang, Yanhui Ao. (2023) Constructing photocatalysis-self-Fenton system over a defective twin C3N4: In-situ producing H2O2 and mineralizing organic pollutants. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2023.122716] |
| 5. Jianwen Zhou, Tianshang Shan, Hao Luo, Bruno Boury, Xia Xu, Hui Wu, Fengshan Zhang, He Xiao. (2023) Enhanced single-electron transfer for efficiently photocatalytic H2O2 production over g-C3N4 decorated with TEMPO-oxidized cellulosic carbon. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2023.109512] |
| 6. Xin Zhang, Qingling Fu, Hongqing Hu, Jun Zhu, Yonghong Liu. (2023) Effects of Fe(II) on As(III) oxidation in Fe(II)-As(III) co-oxidation: Limiting and driving roles. JOURNAL OF HAZARDOUS MATERIALS, [PMID:36669406] [10.1016/j.jhazmat.2023.130790] |
| 7. Qingli Qu, Weixia Cheng, Xiaoli Zhang, Hossein Ravanbakhsh, Guosheng Tang, Aying Zhou, Dong Pei, Ranhua Xiong, Chaobo Huang. (2022) Glucose-Responsive Enzymatic Cascade Microreactors in Gas-Shearing Microfluidics Microcapsules. Advanced Materials Technologies, 8 (5): (2201559). [PMID:] [10.1002/admt.202201559] |
| 8. Chenchong Fu, Cong Pan, Tao Chen, Deqin Peng, Yaqian Liu, Feng Wu, Jing Xu, Zhixiong You, Jinjun Li, Liting Luo. (2022) Adsorption-enforced Fenton-like process using activated carbon-supported iron oxychloride catalyst for wet scrubbing of airborne dichloroethane. CHEMOSPHERE, [PMID:36037963] [10.1016/j.chemosphere.2022.136193] |
| 9. Qingli Qu, Weixia Cheng, Xiaoli Zhang, Aying Zhou, Yankang Deng, Miaomiao Zhu, Tianjiao Chu, Bella B. Manshian, Ranhua Xiong, Stefaan J. Soenen, Kevin Braeckmans, Stefaan C. De Smedt, Chaobo Huang. (2022) Multicompartmental Microcapsules for Enzymatic Cascade Reactions Prepared through Gas Shearing and Surface Gelation. BIOMACROMOLECULES, [PMID:35931466] [10.1021/acs.biomac.2c00324] |
| 10. Cailiang Yue, Changqing Zhu, Wenting Zheng, Jinli Qiu, Zhiling Du, Chen Ling, Fu-Qiang Liu. (2021) Plasmonic Bi NP-accelerated interfacial charge transfer for enhanced solar-driven ciprofloxacin mineralization. Environmental Science-Nano, 9 (1): (349-360). [PMID:] [10.1039/D1EN00896J] |
| 11. Shuangqin Li, Di Liu, Bingyan Wu, Huipeng Sun, Xiaoyan Liu, Haixia Zhang, Nana Ding, Lan Wu. (2021) One-pot synthesis of a peroxidase-like nanozyme and its application in visual assay for tyrosinase activity. TALANTA, [PMID:34838324] [10.1016/j.talanta.2021.123088] |
| 12. Teng Ge, Xiaoli Jin, Jian Cao, Zhuohua Chen, Yixue Xu, Haiquan Xie, Fengyun Su, Xin Li, Qing Lan, Liqun Ye. (2021) Giant enhanced photocatalytic H2O2 production over hollow hexagonal prisms carbon nitride. Journal of the Taiwan Institute of Chemical Engineers, [PMID:] [10.1016/j.jtice.2021.09.036] |
| 13. Qingli Qu, Xiaoli Zhang, Hossein Ravanbakhsh, Guosheng Tang, Jian Zhang, Yankang Deng, Kevin Braeckmans, Stefaan C. De Smedt, Ranhua Xiong, Chaobo Huang. (2021) Gas-shearing synthesis of core–shell multicompartmental microparticles as cell-like system for enzymatic cascade reaction. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2021.132607] |
| 14. Yuqing Wu, Lei Cao, Minghui Zan, Zheng Hou, Mingfeng Ge, Wen-Fei Dong, Li Li. (2021) Iron and nitrogen-co-doped carbon quantum dots for the sensitive and selective detection of hematin and ferric ions and cell imaging. ANALYST, 146 (15): (4954-4963). [PMID:34259240] [10.1039/D1AN00828E] |
| 15. Fangfang Zhou, Jianquan Luo, Siqing Song, Yinhua Wan. (2020) Nanostructured Polyphenol-Mediated Coating: a Versatile Platform for Enzyme Immobilization and Micropollutant Removal. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, [PMID:] [10.1021/acs.iecr.9b05708] |
| 16. Lili Wang, Wencheng Gong, Fang Wang, Zhenya Yu, Zilin Chen. (2016) Efficient bienzyme nanocomposite film for chiral recognition of L-tryptophan, L-phenylalanine and L-tyrosine. Analytical Methods, 8 (17): (3481-3487). [PMID:] [10.1039/C5AY03290C] |
| 17. Wang Fang, Gong Wencheng, Wang Lili, Chen Zilin. (2015) Enhanced amperometric response of a glucose oxidase and horseradish peroxidase based bienzyme glucose biosensor modified with a film of polymerized toluidine blue containing reduced graphene oxide. MICROCHIMICA ACTA, 182 (11): (1949-1956). [PMID:] [10.1007/s00604-015-1535-3] |
| 18. Qixuan Mu, Xinyue Li, Xiuxiu Li, Ruijun Li, Yibing Ji. (2025) Laccase-mimicking active inorganic organic hybrid covalent organic framework filtration membrane for rapid removal of drug pollutants. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.166344] |
| 19. Huan Liu, Yan Wang. (2025) Flow-driven piezoelectric membranes for autonomous antifouling and energy-efficient water purification. DESALINATION, [PMID:] [10.1016/j.desal.2025.119189] |
| 20. Qiansheng Li, Yi Dai, Hong Lu, Xiaoman Li, Fanghao Cheng, Jiti Zhou. (2025) Biological Fenton reaction mediated by N and Fe co-doped carbon dots for ketoprofen degradation. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.118032] |
| 21. Zhuo Liu, Yue Fan, Wanfeng Mao, Dongxu Wang, Lihong Zhao, Duo Meng, Tengfei Wu, Jiaqi Tang. (2025) Self-sustained photo–H2O2 system based on pure g-C3N4: High H2O2 production and rapid pollutant elimination without sacrificial agents. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2025.164570] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →