N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, CAS No.78832-65-2

CAS: 78832-65-2 Cat. No.: N339722 Molecular Weight: 476.52

GRADE & PURITY ≥98%

Overview

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala (FALGPA) is a substrate for the spectrophotometric assay of MMP (collagenase). The isoforms I and II of purified collagenase differ in their specificities and relative activities on native collagen and synthetic substrates. Collagenase II activity is measured by the enzyme's ability to cut a short synthetic peptide, N-[3-(2-Furyl)acryloyl)]-Leu-Gly- Pro-Ala (FALGPA).

Specifications

Product Name

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, CAS No.78832-65-2

Synonyms

FA-Leu-Gly-Pro-Ala-OH | N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala | (3-(Furan-2-yl)acryloyl)-L-leucylglycyl-L-prolyl-L-alanine | FALGPA | N-[3-(2-Furyl)acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanine

Specifications & Purity

≥98%

Sequence

FA-Leu-Gly-Pro-Ala

CAS

78832-65-2

Molecule Type

Peptide

Storage and Shipping

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Leucine and derivatives Proline and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Alanine and derivatives Pyrrolidinecarboxamides N-acylpyrrolidines N-acyl amines Tertiary carboxylic acid amides Furans Heteroaromatic compounds Secondary carboxylic acid amides Oxacyclic compounds Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Hydrocarbon derivatives Carbonyl compounds Organonitrogen compounds Organic oxides
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Alpha-oligopeptide - Leucine or derivatives - Proline or derivatives - N-acyl-l-alpha-amino acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - N-acylpyrrolidine - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Fatty amide - N-acyl-amine - Fatty acyl - Furan - Heteroaromatic compound - Tertiary carboxylic acid amide - Pyrrolidine - Carboxamide group - Secondary carboxylic acid amide - Organoheterocyclic compound - Azacycle - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Organooxygen compound - Organic oxide - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

References

1. Yun Liu, Haibo Zhao, Yishan Fang, Zhengzong Wu, Bin Yu, Bo Cui.  (2024)  Hydrogels of dialdehyde starch and gelatin cross-linked with potential application as tissue adhesives.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39706428] [10.1016/j.ijbiomac.2024.138956]

2. Yahui Xie, Yun Liu, Haibo Zhao, Xuemin Kang, Haiteng Tao, Bin Yu, Bo Cui.  (2026)  Gelatin/starch hydrogel tissue adhesive loaded with EGCG-Zr complex with antibacterial, antioxidant, and immunomodulatory properties for advanced wound healing.  Biomaterials Advances,      [PMID:41690128] [10.1016/j.bioadv.2026.214769]