Narciclasine - Moligand™, 10 mM in DMSO , CAS No.29477-83-6

CAS: 29477-83-6 Cat. No.: N1498586 Molecular Weight: 307.26 EC Number: 687-829-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1OC2=C(O1)C(=C3C(=C2)C4=C[C@@H]([C@H]([C@H]([C@@H]4NC3=O)O)O)O)O
• Molecular Weight: 307.26
• Reaxy-Rn: 1087400
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1087400&ln=

References

1. Xiaoyun Wang, Fengbo Wu, Guoyou Li, Nan Zhang, Xiangrong Song, Yu Zheng, Changyang Gong, Bo Han, Gu He.  (2018)  Lipid-modified cell-penetrating peptide-based self-assembly micelles for co-delivery of narciclasine and siULK1 in hepatocellular carcinoma therapy.  Acta Biomaterialia,      [PMID:29787814] [10.1016/j.actbio.2018.05.030]

2. Ruifang Guo, Yihang Wang, Aiwen Zhang, Siwanon Jirawatnotai, Chen Chu, Lijun Liu.  (2026)  Cyclin D1/D2–CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ–FAK–Rac1 Axis.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  27  (3): (1228).  [PMID:41683655] [10.3390/ijms27031228]