NeurotransRed C₂ [N-(3-Triethylammoniumpropyl)-4-(6-(4-Diethylamino)phenyl)hexatrienyl)Pyridinium Dibromide], FM® 4-64 is TM of Molecular Probes - ≥95%(HPLC) , CAS No.162112-35-8

CAS: 162112-35-8 Cat. No.: N131142 Molecular Weight: 607.506

GRADE & PURITY ≥95%(HPLC)

Synonyms

HY-103466 | AKOS040745380 | FM4-64 | J-009895 | 4-((1E,3E,5E)-6-(4-(diethylamino)phenyl)hexa-1,3,5-trien-1-yl)-1-(3-(triethylammonio)propyl)pyridin-1-ium bromide | 4-(6-(4-(diethylamino)phenyl)hexa-1,3,5-trien-1-yl)-1-(3-(triethylammonio)propyl)pyridin-1-

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Water Soluble Fluorescent RH probe

Specifications

Synonyms

HY-103466 | AKOS040745380 | FM4-64 | J-009895 | 4-((1E, 3E, 5E)-6-(4-(diethylamino)phenyl)hexa-1, 3, 5-trien-1-yl)-1-(3-(triethylammonio)propyl)pyridin-1-ium bromide | 4-(6-(4-(diethylamino)phenyl)hexa-1, 3, 5-trien-1-yl)-1-(3-(triethylammonio)propyl)pyridin-1-

Specifications & Purity

≥95%(HPLC)

Biochemical and Physiological Mechanisms

Fluorescent dye; stains synaptic vesicles. Becomes fluorescent when incorporated into plasma membrane, used to follow synaptic activity at the synapse or neuromuscular junction. Excitation and emission spectra are ~ 515 and 640 nm respectively.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(HPLC)

Names and Identifiers

• Canonical Smiles: CCN(CC)C1=CC=C(C=C1)C=CC=CC=CC2=CC=[N+](C=C2)CCC[N+](CC)(CC)CC.[Br-].[Br-]
• IUPAC Name: 3-[4-[(1E,3E,5E)-6-[4-(diethylamino)phenyl]hexa-1,3,5-trienyl]pyridin-1-ium-1-yl]propyl-triethylazanium;dibromide
• InChIKey: AFVSZGYRRUMOFH-UHFFFAOYSA-L
• INCHI: 1S/C30H45N3.2BrH/c1-6-32(7-2)30-20-18-28(19-21-30)16-13-11-12-14-17-29-22-25-31(26-23-29)24-15-27-33(8-3,9-4)10-5;;/h11-14,16-23,25-26H,6-10,15,24,27H2,1-5H3;2*1H/q+2;;/p-2
• Isomeric SMILES: CCN(CC)C1=CC=C(C=C1)/C=C/C=C/C=C/C2=CC=[N+](C=C2)CCC[N+](CC)(CC)CC.[Br-].[Br-]
• Molecular Weight: 607.506
• Reaxy-Rn: 23884566
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23884566&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Styrenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Styrenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Styrenes
• Alternative Parents: Dialkylarylamines Aniline and substituted anilines Pyridinium derivatives Tetraalkylammonium salts Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organic bromide salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Styrene - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Pyridine - Pyridinium - Quaternary ammonium salt - Tetraalkylammonium salt - Heteroaromatic compound - Tertiary amine - Organoheterocyclic compound - Azacycle - Organic salt - Hydrocarbon derivative - Amine - Organopnictogen compound - Organic nitrogen compound - Organonitrogen compound - Organic bromide salt - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as styrenes. These are organic compounds containing an ethenylbenzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 6.08, Max Conc. mM: 10
• Molecular Weight: 607.500 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 607.196 Da
• Monoisotopic Mass: 605.198 Da
• Topological Polar Surface Area: 7.100 Ų
• Heavy Atom Count: 35
• Formal Charge: 0
• Complexity: 561.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 3
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 3
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Bingnan Wang, Siyuan Wang, Chunyang Li, Jianqing Li, Meixi Yi, Jing-Wen Lyu, Bing Gu, Ryan T.K. Kwok, Jacky W.Y. Lam, Anjun Qin, Ben Zhong Tang.  (2024)  An AIE fungal vacuole membrane probe toward species differentiation, vacuole formation visualization, and targeted photodynamic therapy.  Materials Today Bio,      [PMID:39582780] [10.1016/j.mtbio.2024.101329]