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· · COA & SDS available for every product · Same-day shipping on in-stock items NS 3763 - Moligand™, ≥98%(HPLC) , Antagonist of GluK1, CAS No.70553-45-6, Antagonist of GluK1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
NCGC00092326-01 | UNII-R4HH3BUP3T | NS 3763 | NS3763 | NS-3763 | 4,6-Dibenzamidoisophthalic acid | Q27088064 | BDBM50137133 | GTPL4274 | 1,3-Benzenedicarboxylic acid, 4,6-bis(benzoylamino)- | 4,6-dibenzamidobenzene-1,3-dicarboxylic acid | 4,6-Bis(benzamid
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
NCGC00092326-01 | UNII-R4HH3BUP3T | NS 3763 | NS3763 | NS-3763 | 4, 6-Dibenzamidoisophthalic acid | Q27088064 | BDBM50137133 | GTPL4274 | 1, 3-Benzenedicarboxylic acid, 4, 6-bis(benzoylamino)- | 4, 6-dibenzamidobenzene-1, 3-dicarboxylic acid | 4, 6-Bis(benzamid
Specifications & Purity
Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms
Selective non-competitive kainate receptor antagonist; displays selectivity for GluK1 (formerly GLUK5) subunit-containing receptors (IC50values are 1.6 and > 30μM for homomeric GluK1 (formerly GLUK5) and GluK2 (formerly GLUK6) receptors respectively). Ha
Mechanism of action
Antagonist of GluK1
Names and Identifiers Canonical Smiles C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2C(=O)O)C(=O)O)NC(=O)C3=CC=CC=C3 IUPAC Name 4,6-dibenzamidobenzene-1,3-dicarboxylic acid InChIKey UUDYZUDTQPLDDP-UHFFFAOYSA-N INCHI 1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30) Isomeric SMILES C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2C(=O)O)C(=O)O)NC(=O)C3=CC=CC=C3 WGK Germany 3 Molecular Weight 404.38 Reaxy-Rn 9807755 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9807755&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Anilides Intermediate Tree Nodes Aromatic anilides Direct Parent Benzanilides Alternative Parents M-phthalic acid and derivatives Benzoic acids Benzamides Benzoyl derivatives Vinylogous amides Secondary carboxylic acid amides Carboxylic acids Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic homomonocyclic compounds Substituents Benzanilide - Meta_phthalic_acid - Benzamide - Benzoic acid or derivatives - Benzoic acid - Benzoyl - Vinylogous amide - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound Description This compound belongs to the class of organic compounds known as benzanilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with a benzene ring. They have the general structure RNC(=O)R', where R,R'= benzene. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 10.11, Max Conc. mM: 25 Molecular Weight 404.400 g/mol XLogP3 3.700 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 6 Exact Mass 404.101 Da Monoisotopic Mass 404.101 Da Topological Polar Surface Area 133.000 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 600.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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