Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Nuciferine is an antagonist at 5-HT 2A ( IC 50 =478 nM), 5-HT 2C ( IC 50 =131 nM), and 5-HT 2B ( IC 50 =1 μM), an inverse agonist at 5-HT 7 ( IC 50 =150 nM), a partial agonist at D 2 ( EC 50 =64 nM), D 5 ( EC 50 =2.6 μM) and 5-HT 6 ( EC 50 =700 nM), an agonist at 5-HT 1A ( EC 50 =3.2 μM) and D 4 ( EC 50 =2 μM) receptor.
| Isomeric SMILES | CN1CCC2=CC(=C(C3=C2[C@H]1CC4=CC=CC=C43)OC)OC |
|---|---|
| Molecular Weight | 295.376 |
| Reaxy-Rn | 91203 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=91203&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Yuhuan Chen, Qiwen Chen, Xiaozhong Wang, Fan Sun, Yawei Fan, Xiaoru Liu, Hongyan Li, Zeyuan Deng. (2019) Hemostatic action of lotus leaf charcoal is probably due to transformation of flavonol aglycons from flavonol glycosides in traditional Chinses medicine. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:31678413] [10.1016/j.jep.2019.112364] |
| 2. Li Zizhuo, Chen Yaodong, An Tingting, Liu Pengfei, Zhu Jiyuan, Yang Haichao, Zhang Wei, Dong Tianxiu, Jiang Jian, Zhang Yu, Jiang Maitao, Yang Xiuhua. (2019) RETRACTED ARTICLE: Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 38 (1): (1-15). [PMID:30922391] [10.1186/s13046-019-1134-y] |
| 3. Lina Zhang, Jinghua Gao, Peng Tang, Li Chong, Yue Liu, Peng Liu, Xin Zhang, Li Chen, Chen Hou. (2018) Nuciferine inhibits LPS-induced inflammatory response in BV2 cells by activating PPAR-γ. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:30056259] [10.1016/j.intimp.2018.07.015] |
| 4. Shixiang Chen, Bochen Wei, Lili Wen, Penglian Wei, Yunlin Fu. (2024) Metabolomics analysis of bioactive compositions of Michelia macclurei Dany and its antioxidant and enzyme inhibitory activities. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 105 (1): (635-648). [PMID:39230063] [10.1002/jsfa.13860] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
