Phenylbutazone(diphenyl-d10) - ≥98% , CAS No.1219794-69-0

CAS: 1219794-69-0 Cat. No.: P648935 Molecular Weight: 318.44

GRADE & PURITY ≥98%

Synonyms

Phenylbutazone-d10 | DTXSID501016401 | 1219794-69-0 | Phenylbutazone(diphenyl-d10) | 4-butyl-1,2-bis(2,3,4,5,6-pentadeuteriophenyl)pyrazolidine-3,5-dione | HY-B0230S | MS-24704 | F91237

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Phenylbutazone(diphenyl-d 10 ) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Synonyms

Phenylbutazone-d10 | DTXSID501016401 | 1219794-69-0 | Phenylbutazone(diphenyl-d10) | 4-butyl-1, 2-bis(2, 3, 4, 5, 6-pentadeuteriophenyl)pyrazolidine-3, 5-dione | HY-B0230S | MS-24704 | F91237

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Phenylbutazone(diphenyl-d 10 ) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agen

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
• IUPAC Name: 4-butyl-1,2-bis(2,3,4,5,6-pentadeuteriophenyl)pyrazolidine-3,5-dione
• InChIKey: VYMDGNCVAMGZFE-MIPJZDBJSA-N
• INCHI: 1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3/i4D,5D,6D,7D,8D,9D,10D,11D,12D,13D
• Isomeric SMILES: [2H]C1=C(C(=C(C(=C1[2H])[2H])N2C(=O)C(C(=O)N2C3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H])CCCC)[2H])[2H]
• Alternate CAS: 1219794-69-0
• Molecular Weight: 318.44
• Reaxy-Rn: 290080
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=290080&ln=