GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)See COA
Carrier Free,His-Tag,≥90%(SDS-PAGE),See COA Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications
Product Name
Recombinant Human DNA-PKcs Protein
Synonyms
DNA dependent protein kinase catalytic subunit | DNA PK catalytic subunit | DNA-dependent protein kinase catalytic subunit | DNA-PK catalytic subunit | DNA-PKcs | DNAPK | DNAPK catalytic subunit | DNPK 1 | DNPK1 | Hyper radiosensitivity of murine scid mut
Grade
Carrier Free, His Tag
Specifications & Purity
Carrier Free, His-Tag, ≥90%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms
PRKDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial for DNA double-strand break repair and V(D)J recombination. PRKDC expression was significant
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ for 6 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Human DNA-PKcs Protein (rp184914) - SDS-PAGE 3 μg/lane of Recombinant Human DNA-PKcs Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 27.3 & 53.3 & 88.1 kDa under reducing conditions and 23.4 & 26.0 & 27.3 & 49.7 & 75.7 kDa under non-reducing conditions. This expression region contains multiple phosphorylation post-translational modification sites, which may influence its aggregation state. The self phosphorylation of DNA-PKcs induces conformational changes, which leads to the remodeling of the DNA-PK complex. This is essential for efficient end processing and DNA repair (PMID: 33854234).
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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