GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)
Expression System
HEK293
Accession #
AAH67736
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<0.1 EU/μg
Bioactivity
Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,His-Tag,≥90%(SDS-PAGE) ActiBioPure™,Animal Free,Bioactive,Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Specifications
Product Name
Recombinant Human RGM-B Protein
Synonyms
Repulsive Guidance Molecule B | DKFZp434P228 | Dragon | DRG11-responsive axonal guidance and outgrowth of neurite | RGM domain family, member B | RGMB | RGM-B
Grade
ActiBioPure™, Animal Free, Bioactive, Carrier Free, His Tag
Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
18 kDa (N-terminus chain) and 35 kDa (C-terminus chain), under reducing conditions; 45 kDa (Full-length protein), under non-reducing conditions.
Molecule Type
Protein
Storage and Shipping
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~-80℃ for more than 1 year. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Human RGM-B Protein (rp166982) - Protein Bioactivity Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
Recombinant Human RGM-B Protein (rp166982) - SDS-PAGE 2 μg/lane of Recombinant Human RGM-B Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 18 kDa (N-terminus chain) and 35 kDa (C-terminus chain) under reducing conditions and 45 kDa (Full-length protein) under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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